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Vindesine

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Definition: Vinblastine derivative with antineoplastic activity against CANCER. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS).     
Pharmacological Action Antineoplastic Agents, Phytogenic; Tubulin Modulators
Other names Sulfate, Vindesine; NSC245467; NSC 245467; Vindesine Sulfate; Vindesin; NSC-245467; Lilly Brand of Vindesine Sulfate; Enison; Eldisine; EG Labo Brand of Vindesine Sulfate; Desacetylvinblastine Amide; Compound 112531
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MOPPEBVCAD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Doxorubicin/*analogs & derivatives Lomustine Mechlorethamine Melphalan Prednisone Procarbazine Vinblastine Vincristine Vindesine. J Clin Oncol. 2005 Dec 20;23(36):9198-207
BEMP protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Vindesine Mitomycin. Ann Oncol 2001 Jul;12(7):967-74
OPP-EBV-CAD regimen  0   *Antineoplastic Combined Chemotherapy Protocols Prednisone Vincristine Vindesine Epirubicin. Leuk Lymphoma 2000 Dec;40(1-2):87-94
Cis-VACD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cyclophosphamide Dexamethasone Doxorubicin Vindesine. Leuk Lymphoma 1999 Nov;35(5-6):613-8
HELP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Ifosfamide Methotrexate Vindesine. Ann Oncol 1999 Sep;10(9):1065-71
LSG15 regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Etoposide Nitrosourea Compounds Prednisolone Vincristine Vindesine Carboplatin. Int J Hematol 1999 Feb;69(2):92-5
VQEP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carbazilquinone Cyclophosphamide Prednisolone Vindesine. Br J Cancer 1997;76(11):1484-8
VEMP protocol 3  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Methotrexate Prednisolone Vindesine. Br J Cancer 1997;76(11):1484-8
HR-2 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Daunorubicin Dexamethasone Ifosfamide Methotrexate Prednisolone Thioguanine Vindesine. Blood 1996 Apr 15;87(8):3143-50
EPVP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Prednisolone Procarbazine Vindesine. Gan To Kagaku Ryoho 1996 Mar;23(4):499-501
LNH 87 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Prednisone Vindesine. Blood 1996 Jan 1;87(1):265-72
PECC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carmustine Cyclophosphamide Prednisone Vindesine. J Clin Oncol 1994 Dec;12(12):2706-13
OS 87 protocol  0   Cisplatin Doxorubicin *Antineoplastic Combined Chemotherapy Protocols Leucovorin Ifosfamide Methotrexate Vindesine. J Clin Oncol 1994 Dec;12(12):2614-20
CEVD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Etoposide Lomustine Vindesine. Leuk Lymphoma 1994 Jun;14(1-2):79-89
PEEC-M protocol  0   *Antineoplastic Combined Chemotherapy Protocols Chlorambucil Etoposide Methotrexate Methylprednisolone Vindesine. Br J Cancer 1994 Sep;70(3):501-5
MCNU-VMP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Melphalan Nitrosourea Compounds Prednisolone Vindesine. Int J Hematol 1994 Feb;59(2):113-23
DVP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Dacarbazine Vindesine. Am J Clin Oncol 1994 Feb;17(1):55-9
MICE regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Ifosfamide Vindesine Mitomycin. Eur J Cancer 1993;29A:1848-50
LNH87-2 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Methotrexate Methylprednisolone Vindesine. Ann Oncol 1993 Sep;4(8):651-6
VIP protocol 3  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Ifosfamide Vindesine. Am J Clin Oncol 1993 Aug;16(4):310-4
CAD protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Lomustine Vindesine. J Clin Oncol 1993 Apr;11(4):712-9
LNH-80 regimen  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Vindesine. Ann Oncol 1992 Sep;3(8):639-44
MV protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Vindesine Mitomycin. Cancer Chemother Pharmacol 1992;30(3):212-4
IVEP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Prednisolone Vindesine. Hematol Oncol 1991;9(4-5):217
MTV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Thiotepa Vindesine Mitomycin. Ann Oncol 1991;2(5):347
VAE protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Vindesine. Br J Haematol 1991;77(4):486
EV protocol  0   Vindesine *Antineoplastic Combined Chemotherapy Protocols Etoposide. Ann Oncol 1990;1(2):128
PCV regimen  0   Cisplatin *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Vindesine. Cancer 1990;65(11):2435
MB-triple V protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine/analogs & derivatives Etoposide Mitoxantrone Vincristine Vindesine. Gan To Kagaku Ryoho 1989;16(12):3729
VINAP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Lomustine Prednisolone Vindesine. Sangre (Barc) 1989;34(2):107
LNH 84 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Prednisolone Vindesine. J Clin Oncol 1989;7(8):1018
PEEC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Chlorambucil Etoposide Methylprednisolone Vindesine. Scott Med J 1988;33(6):360
EVI protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Vindesine. Eur J Cancer Clin Oncol 1987;23(8):1197
VMMc protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitomycins Mitoxantrone Vindesine. Cancer Treat Rep 1987;71(9):845
VPIV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Podophyllotoxin Vindesine. Cancer Chemother Pharmacol 1986;18 Suppl 2:S40
MiPE protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Vindesine Mitomycin. Cancer Treat Rep 1986;70(9):1091
N-(4-azido-3-iodosalicyl)-N'-beta-aminoethylvindesine  102976-56-7   *Azides Vindesine/*analogs & derivatives. J Biol Chem 1986;261(14):6137
N-(4-azidobenzoyl)-N'-beta-aminoethylvindesine  103974-27-2   *Azides Vindesine/*analogs & derivatives. J Biol Chem 1986;261(14):6137
VinMCP protocol  0   Melphalan *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Prednisone Vindesine. Cancer 1986;57(2):226
ELETOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Vindesine. Cancer 1986;57(1):44
VDA-P protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Vindesine. J Clin Oncol 1986;4(1):14
APEL protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Vindesine. Presse Med 1985;14(19):1069
VCPC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cyclophosphamide Lomustine Vindesine. Bull Cancer (Paris) 1985;72(1):25
BELD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Dacarbazine Lomustine Vindesine. Cancer 1985;55(9):1879
VEP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Prednisolone Vindesine. Semin Oncol 1985;12(1 Suppl 2):26
VCH protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Altretamine Vindesine. Cancer Treat Rep 1984;68(9):1179
EBAP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carmustine Doxorubicin Prednisone Vindesine. Cancer Treat Rep 1984;68(7-8):963
CAPE protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Prednisone Vindesine. Neth J Med 1984;27(2):25
CAD protocol 1  0   *Antineoplastic Combined Chemotherapy Protocols Lomustine Melphalan Vindesine. Am J Med 1984;76(2):270
DAC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Vindesine. Cancer 1983;52(7):1142
DECAV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Dacarbazine Cyclophosphamide Doxorubicin Vindesine. Sem Hop Paris 1983;59(19):1441
CVB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Vindesine. Cancer 1983;51(6):1050

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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