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Xanthines

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Definition: Purine bases found in body tissues and fluids and in some plants.  do not confuse with XANTHENES; XANTHINE is also available   
Examples Caffeine; Theobromine; Theophylline; Uric Acid; Xanthine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bisdionin F  0   *Xanthines Chitinase/antagonists & inhibitors. Chem Biol 2011 May 27;18(5):569-79
1-butyl-8-(3-noradamantyl)-3-(3-hydroxypropyl)xanthine  0   *Xanthines Receptor, Adenosine A1. Cell Biochem Funct 2008 Dec;26(8):833-43
xanthienopyran  0   *Pyrans *Xanthines. Planta Med. 2008 Aug;74(10):1276-9
xanthialdehyde  0   *Aldehydes *Xanthines. Planta Med. 2008 Aug;74(10):1276-9
cellulose xanthate  0   *Xanthines Cellulose/*analogs & derivatives. Carbohydr Res 1975 May;41:227-33
1,3-dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine  0   *Pyrazoles *Xanthines. Bioorg Med Chem. 2008 Mar 1;16(5):2419-30
NN 7201  0   *Xanthines.
Pharma Action Dipeptidyl-Peptidase IV Inhibitors 		Am J Physiol Gastrointest Liver Physiol 2007 Jul;293(1):G288-95
1-propyl-8-(4-sulfophenyl)xanthine  0   *Xanthines Receptor, Adenosine A2B/antagonists & inhibitors. J Med Chem 2004 Feb 12;47(4):1031-43
8-(3-Chlorostyryl)-1,3,7-trimethylxanthine  0   *Xanthines. Acta Crystallogr C. 2005 Sep;61(Pt 9):o531-2
9-butyl-2-(3-noradamantyl)-4,5-dihydro-6H,8H-pyrimido(1,2,3-cd)purine-8,10-dione  0   *Xanthines Adamantane/*analogs & derivatives Receptor, Adenosine A1/antagonists & inhibitors. ChemMedChem 2006 Aug;1(8):891-902
1-butyl-3-(3-hydroxypropyl)-8-(3-noradamantyl)xanthine  0   *Xanthines Adamantane/*analogs & derivatives Receptor, Adenosine A1/antagonists & inhibitors. ChemMedChem 2006 Aug;1(8):891-902
8-(4-(4-benzylpiperazide-1-sulfonyl)phenyl)-1-propylxanthine  0   *Sulfonamides *Xanthines Receptor, Adenosine A2B/antagonists & inhibitors. J Med Chem 2006 Jul 13;49(14):4384-91
xanthophyll plectaniaxanthin  0   *Xanthines *Xanthophylls. Phytochemistry. 2005 Nov;66(22):2617-26
7-(2-(4-(2-nitrobenzene)piperazinyl)ethyl)-1,3-dimethylxanthine  0   *Piperidines *Xanthines. J Cardiovasc Pharmacol 2005 Nov;46(5):600-8
7-(2-(4-(4-nitrobenzene)piperazinyl)ethyl)-1,3-dimethylxanthine  0   *Piperidines *Xanthines. J Cardiovasc Pharmacol 2005 Nov;46(5):600-8
BG 9928  0   *Xanthines Receptor, Adenosine A1. Curr Opin Investig Drugs 2005 Sep;6(9):962-8
8-(4-(((1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl)amino)-2-oxoethoxy)phenyl)-1-propylxanthine  0   *Cyclic N-Oxides *Xanthines. J Med Chem 2005 Mar 24;48(6):2108-14
8-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)-1,3-dipropylxanthine  0   *Cyclic N-Oxides *Xanthines. J Med Chem 2005 Mar 24;48(6):2108-14
8-cyclopentyl-3-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-ylmethyl)-1-propylxanthine  0   *Cyclic N-Oxides *Xanthines. J Med Chem 2005 Mar 24;48(6):2108-14
6,8-dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo(2,3-f)xanthine  0   *Piperidines *Thiazoles *Xanthines. Eksp Klin Farmakol. 2004 Jul-Aug;67(4):44-6
1-methyl-3-propyl-7-N,N-dimethylpropylamide-xanthine  0   *Xanthines. Toxicol Lett. 2004 May 2;150(3):341-9
1,7-dimethyl-8-nitroxanthine  0   *Xanthines. Cancer Sci 2004 Apr;95(4):361-6
1,8-dibenzylxanthine  0   *Xanthines. Bioorg Med Chem Lett. 2003 Nov 3;13(21):1871-4
8-cyclopentyl-3-(3-iodoprop-2-en-1-yl)-1-propylxanthine  0   *Xanthines Iodine Radioisotopes Receptor, Adenosine A1/antagonists & inhibitors. Nucl Med Biol 2003 Aug;30(6)661-8
1-butyl-8-(4-((4-nitrophenoxy)sulfonyl)phenyl)xanthine  0   *Sulfonic Acids *Xanthines Receptor, Adenosine A1/antagonists & inhibitors Receptors, Adenosine A2/antagonists & inhibitors. J Med Chem 2004 Feb 12;47(4):1031-43
1-propyl-8-(4-((4-nitrophenoxy)sulfonyl)phenyl)xanthine  0   *Sulfonic Acids *Xanthines Receptor, Adenosine A1/antagonists & inhibitors Receptors, Adenosine A2/antagonists & inhibitors. J Med Chem 2004 Feb 12;47(4):1031-43
8-cyclopenta-3-(3-fluoropropyl)-1-propylxanthine  0   *Xanthines Fluorine Radioisotopes Receptors, Purinergic P1/antagonists & inhibitors. J Med Chem 2002 Nov 7;45(23):5150-6
cipamfylline  0   *Xanthines Phosphodiesterase Inhibitors. Br J Pharmacol 2002 Aug;147(2):299-7
8-hexylthio-xanthine  0   Xanthines. Farmaco 2001 Nov;56(11):809-13
1-methyl-8-dicyclopropylmethyl-1-methyl-3-propylxanthine  0   *Xanthines Carbon Radioisotopes. Nucl Med Biol 2002 Jan;29(1):29-37
keto-myxocoxanthin glucoside ester  0   *Carotenoids *Xanthines. Plant Cell Physiol 2001 Dec;42(12):1355-62
methoxy-keto-myxocoxanthin  0   *Carotenoids *Xanthines. Plant Cell Physiol 2001 Dec;42(12):1355-62
9-ethyl-8-nitoxanthine  0   *Xanthines. Chem Res Toxicol 2002 Jan;15(1):7-14
1-(8-phosphonooctyl)-7-deazaxanthine  0   *Xanthines Thymidine Phosphorylase/antagonists & inhibitors. FEBS Lett 2002 Jan 2;510(1-2):83-8
KMCP 98  0   *Xanthines Receptors, Purinergic P1/agonists. Gen Pharmacol 2000 Jul;35(1):47-57
3-isobutyl-8-pyrrolidinoxanthine  0   *Pyrrolidinones *Xanthines. Biochem Pharmacol 2001 Nov 1;62(9):1163-73
KMUP 1  0   *Xanthines *Piperidines. Br J Pharmacol 2001 Sep;134(2):265-74
5-aza-7-deazaxanthine  0   *Aza Compounds *Xanthines. J Org Chem 2001 Jul 27;66(15):5012-5
8-Nitroxanthine  0   *Xanthines. Chem Res Toxicol 2001 May;14(5):536-46
8-cyclopentyl-3-(3-(4-fluorosulfonylbenzamido)propyl)-1-propylxanthine  0   *Xanthines Receptors, Purinergic P1/antagonists & inhibitors. J Med Chem 2000 Dec 28;43(26):4973-80
X 33 compound  0   *Xanthines. Am J Physiol Cell Physiol 2000 Dec;279(6):C1925-37
(H(3))3-(3-hydroxypropyl)-7-methyl-8-(m-methoxystyryl)-1-propargylxanthine  0   *Styrenes *Xanthines. Eur J Pharm Sci 2000 ;10(4):259-65
MRS 1595  0   *Xanthines Receptors, Purinergic P1/antagonists & inhibitors. J Med Chem 2000 Mar 23;43(6):1165-72
MRS 1204  0   *Xanthines Receptors, Purinergic P1/antagonists & inhibitors. J Med Chem 2000 Mar 23;43(6):1165-72
1,3-dibutyl-7-(3-chloropropane-1-sulfonyl)-3,7-dihydropurine-2,6-dione  0   *Sulfonamides *Xanthines. J Med Chem 2000 Mar 23;43(6):1223-33
KF18446  0   *Xanthines Carbon Radioisotopes Ligands. J Nucl Med 2000 Feb;41(2):345-54
8-methoxymethyl-3-isobutyl-1-methylxanthine  0   *Xanthines Isoenzymes/antagonists & inhibitors. Life Sci 1999;64(23):2081-8
7-2-2-(3,4-dihydroxy-phenyl-2-hydroxyethyl-aminoethyl)-theophylline  0   Theophylline/*analogs & derivatives Xanthines. Actas Luso Esp Neurol Psiquiatr Cienc Afines 1998; Sep-Oct;26(5):333-8
xanthine 5'-O-(3-thiotriphosphate)  0   *Thionucleotides *Xanthines. J Biol Chem 1998 Nov 13;273(46):30183-8
7-deazaxanthine  0   *Xanthines Thymidine Phosphorylase/antagonists & inhibitors. FEBS Lett 1998 Oct 30;438(1-2):91-5
nidulalin A  0   Xanthines. J Antibiot (Tokyo) 1997 Jul;50(7):614-6
F 390C  0   Xanthines. J Antibiot (Tokyo) 1997 Jul;50(7):614-6
F 390B  0   Xanthines. J Antibiot (Tokyo) 1997 Jul;50(7):614-6
MSX 3 compound  0   *Xanthines. Neuroreport 1998 Jun 1;9(8):1803-6
MSX 2 compound  0   *Xanthines Receptors, Purinergic P1/antagonists & inhibitors. Neuroreport 1998 Jun 1;9(8):1803-6
1,3-dimethyl-8-cyclopentylxanthine  0   *Xanthines. Biochem Biophys Res Commun 1998 May 29;246(3):888-94
1-methyl-3-propyl-7-butylxanthine  0   *Xanthines. Jpn J Cancer Res 1998 Feb;89(2):228-33
1,3-diallyl-8-cyclohexylxanthine  0   *Xanthines. J Biol Chem 1998 Mar 6:273(10):5727-34
8-dipropyl-8-cyclopentylxanthine  0   *Xanthines Receptors, Purinergic P1/antagonists & inhibitors. Pharmacol 1997 Jun;80(6):295-300
CT 2584  166981-13-1   *Xanthines Phospholipase D/antagonists & inhibitors. Free Radic Biol Med 1997;22(3):497-507
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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