encyclopedia of medical concepts
ψ 
ψ 
ψ 

Zearalenone

More information in Books or onNLM PubMed
Definition: (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.  a mycotoxin & non-steroidal estrogen; do not confuse with zearalanone (index under ZEARALENONE /analogs)   
Pharmacological Action Estrogens, Non-Steroidal
Examples Zeranol 		Other names F-2 Toxin; Toxin, F2; Toxin, F-2; F 2 Toxin; F2 Toxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-hydroxylasiodiplodin  0   Zearalenone/*analogs & derivatives. Biosci Biotechnol Biochem 2009 Nov;73(11):2512-4
11-alpha-methoxycurvularin  0   Zearalenone/*analogs & derivatives Stereoisomerism. J Org Chem 2007 Dec 7;72(25):9846-9
S14-95  0   Zearalenone/*analogs & derivatives. Mol Pharmacol 2003 Feb;63(2):383-91
lasiodiplodin  0   Zearalenone/*analogs & derivatives. J Org Chem 2000 Nov 17;65(23):7990-5
zearalenone 6'-carboxymethyloxime  0   *Oximes Zearalenone/*analogs & derivatives. Prikl Biokhim Mikrobiol 2000 May-Jun;36(3):328-35
5-7-oxo-zeaenol  0   Zearalenone/*analogs & derivatives. Int J Immunopharmacol 1999 Dec;21(12):799-814
hypothemycin  0   Zearalenone/analogs & derivatives. Life Sci 1999;65(4):381-94
zearalenone-4-sulfate  132505-04-5 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-16-hydroxy-3-methyl-14-(sulfooxy)-, (S-(E))  Zearalenone/*analogs & derivatives. Appl Environ Microbiol 1991;57(1):146
zearalenone-4-glucopyranoside  105088-14-0   *Glucosides Zearalenone/*analogs & derivatives. Appl Environ Microbiol 1986;52(3):515
10-dihydrocurvularin  95416-14-1 2H-3-Benzoxacyclododecin-2-one, 1,4,5,6,7,8,9,10-octahydro-10,11,13-trihydroxy-4-methyl-, (8S-cis)  Zearalenone/*analogs & derivatives. J Pharm Sci 1984;73(12):1846
taleranol  42422-68-4   *Zearalenone. Farmaco (Sci) 1980;35(5):425
dehydrocurvularin  21178-57-4 4,5,6,7-tetrahydro-11,13-dihydroxy-4-methyl-2H-3- benzoxacyclododecin-2,10-(1H)-dione  Zearalenone/analogs & derivatives. Planta Med 31(1):31;1977
curvularin  10140-70-2   Zearalenone/*analogs & derivatives. J Environ Sci Health B11(4):289;1976; Neoplasma 24(1):21;1977
8'-hydroxyzearalenone  40785-64-6 3,4,5,6,9,10-hexahydro-5,14,16-trihydroxy-3- methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione  Zearalenone/*analogs & derivatives Mycotoxins. J Agric Food Chem 22(6):1015;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy