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1-Carboxyglutamic Acid

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Definition: Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kidney protein, in bone protein, and in the protein present in various ectopic calcifications.  /biosyn /physiol permitted    Other names gamma-Carboxyglutamic Acid; gamma-Carboxyglutamate; gamma Carboxyglutamic Acid; gamma Carboxyglutamate; 1 Carboxyglutamic Acid; 3-Amino-1,1,3-propanetricarboxylic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
matrix Gla protein  0   *Calcium-Binding Proteins *Extracellular Matrix Proteins Bone and Bones Vitamin K 1-Carboxyglutamic Acid. J Biol Chem 1985;260(28):14971
n-heptafluorobutyryl isobutyl ester of gamma-carboxyglutamic acid  95654-14-1   1-Carboxyglutamic Acid/*analogs & derivatives. J Chromatogr 1985;319(3):404
N-carbobenzoxy-(gamma,gamma'-di-tert-butyl)-gamma-carboxyglutamylglycine ethyl ester  56926-93-3 glycine, N-(4-((1,1-dimethylethoxy)carbonyl)-N-((phenylmethxy)carbonyl)-DL-alpha-glutamyl)-, 5-(1,1-dimethylethyl) 1-ethyl ester  1-Carboxyglutamic Acid/*analogs & derivatives. Biochim Biophys Acta 1979;579:466
gamma-glutamyl-3-carboxy-4-nitroanilide  53602-84-9 Benzoic acid, 5-((4-amino-4-carboxy-1-oxobutyl)amino)-2-nitro-, (S)  1-Carboxyglutamic Acid/*analogs & derivatives. Clin Chim Acta 72(2):205;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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