encyclopedia of medical concepts
ψ 

3-Hydroxysteroid Dehydrogenases

More information in Books or onNLM PubMed
Definition: Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids.     
Examples 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Cholesterol Oxidase; Progesterone Reductase 		Other names 3-beta-Hydroxysteroid Dehydrogenase; Hydroxysteroid Dehydrogenases, 3; Dehydrogenases, 3-Hydroxysteroid; Dehydrogenases, 3 Hydroxysteroid; Dehydrogenase, 3-beta-Hydroxysteroid; 3 beta Hydroxysteroid Dehydrogenase; 3 Hydroxysteroid Dehydrogenases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Lyngstadaas syndrome  0   *Tooth, Supernumerary/genetics *Steroid Metabolism, Inborn Errors 3-Hydroxysteroid Dehydrogenases/deficiency. Clin Genet. 49(5):249-54
Nsdhl protein, mouse  EC 1.1.-   *3-Hydroxysteroid Dehydrogenases. Nat Genet 1999 Jun;22(2):182-7
3beta-hydroxysteroid dehydrogenase 4, mouse  EC 1.1.-   *3-Hydroxysteroid Dehydrogenases. Am J Physiol Renal Physiol 2006 Jul;291(1):F218-24
AKR1C3 protein, human  EC 1.1.1.-   *Hydroxyprostaglandin Dehydrogenases *3-Hydroxysteroid Dehydrogenases. Biochemistry. 2004 Mar 2;43(8):2188-98
Nsdhl protein, human  EC 1.1.1.170   *3-Hydroxysteroid Dehydrogenases. Biochim Biophys Acta 2003 Sep 23;1651(1-2):36819-29
3 beta-hydroxy-delta 5-steroid dehydrogenase, rat  EC 1.1.1.51   *3-Hydroxysteroid Dehydrogenases. Steroids. 2002 Dec;67(13-14):1071-7
DHRS9 protein, human  EC 1.1.-   *3-Hydroxysteroid Dehydrogenases. J Biol Chem 2001 Jun 29;276(26):24194-202
3,5,3',5'-tetraiodothyropropionic acid  0   Thyroxine/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases. Org Lett 2000 Aug 24;2(17):121-8
3-dehydroecdysone 3alpha-reductase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. Biochem Soc Trans 1996 Aug;24(3):436S
3-dehydroecdysone 3beta-reductase  EC 1.1.3.-   *3-Hydroxysteroid Dehydrogenases. Eur J Biochem 1996 Dec 1;242(2):394-401
3 alpha-hydroxysteroid-5 beta-oxidoreductase  EC 1.1.1-   *3-Hydroxysteroid Dehydrogenases. Z Naturforsch (C) 1993 Sep-Oct;48(9-10):713-21
ERG26 protein, S cerevisiae  EC 1.1.1.170   *3-Hydroxysteroid Dehydrogenases *Saccharomyces cerevisiae Proteins. Appl Environ Microbiol 1991;57(5):1386
3-bromoacetoxyandrostan-17-one  83456-59-1   Androsterone/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. J Biol Chem 1991;266(14):8826
3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. J Biol Chem 1981;256(7):3376
5alpha-androstane-3beta-hydroxysteroid dehydrogenase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. Acta Endocrinol (Copenh) 1990;122(3):289
5alpha-androstane-3alpha-hydroxysteroid dehydrogenase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. Acta Endocrinol (Copenh) 1990;122(3):289
1-(4'-nitrophenyl)-2-propen-1-ol  123232-63-3   *Nitrobenzenes 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem J 1989;262(1):139
1-(4'-nitrophenyl)-2-propyn-1-ol  78725-73-2   *Nitrobenzenes 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem J 1989;262(1):139
3-alpha-hydroxyglycyrrhetinate dehydrogenase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. J Bichem (Tokyo) 1988;103(3):504
17-(3'-hydroxypropyl)-1,3,5,6,8(9)-estrapentaene-3,17-diol  93239-10-2   Equilenin/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. J Reprod Fertil 1985;75(2):393
2-cyanoprogesterone  95160-20-6   Progesterone/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem J 1985;226(2):469
4-ethenylideneandrostane-3,17-dione  84958-35-0 Androstane-3,17-dione, 4-ethenylidene-, (5alpha)  Androstane-3,17-diol/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Steroids 1982;40(1):109
4-ethenylideneandrostane-3,17-diol  84958-36-1 Androstane-3,17-diol, 4-ethenylidene-, (3beta,5alpha,17beta)  Androstane-3,17-diol/*analogs & derivatives 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Steroids 1982;40(1):109
delta(5)-3 beta-hydroxysteroid dehydrogenase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. Biochem Biophys Res Commun 1981;101(2):495
3-ketosteroid reductase  EC 1.1.1.-   3-Hydroxysteroid Dehydrogenases. Arch Biochem Biophys 1981;211(1):430
NAD 3 alpha-hydroxy-5 alpha-pregnan-20-one-oxidoreductase  EC 1.1.1.-   *3-Hydroxysteroid Dehydrogenases. Steroids 1980;36(2):167
3-hydroxycholanate dehydrogenase  EC 1.1.1.52   *3-Hydroxysteroid Dehydrogenases. Cancer 36(Conference Suppl 6):2387;1975
ecdysone oxidase  EC 1.1.3.16   *3-Hydroxysteroid Dehydrogenases. Eur J Biochem 89(2):453;1978; Hoppe Seylers Z Physiol Chem 359(10):1315;1978
17 beta-hydroxy-4,4,17 alpha-trimethylandrost-5-eno(2,3-d)isoxazole  25615-25-2 2,3-dihydro-4,4,17-trimethylandrosta-2,5-dieno(2,3-d)isoxazol-17 beta-ol  *Isoxazoles 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem Biophys Res Commun 80(3):668;1978
17-hydroxy-17-methyl-3-oxospiro(androst-5-ene-4,1'-cyclopropane)-2-carbonitrile  50303-11-2   *Androstenols 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem Biophys Res Commun 80(3):668;1978
trilostane  13647-35-3   Dihydrotestosterone/*analogs & derivatives Oxidative Phosphorylation Coupling Factors 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors.
Pharma Action Abortifacient Agents, Steroidal ; Antineoplastic Agents ; Enzyme Inhibitors 		Endocrinology 103(4):1411;1978; Endocrinology 97(1):136;1975; Fertil Steril 1979;32(4):464; J Endocrinol 76:293;1978; Steroids 32(2):257;1978MODRASTANE

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy