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Oxyquinoline

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Definition: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.  DF: note short X ref   
Examples Chloroquinolinols; Clioquinol; Iodoquinol 		Other names Oxyquinol; Oxine; 8-Quinolinol; Sulfate, Oxyquinoline; Sulfate, 8-Hydroxyquinoline; 8 Quinolinol; 8 Oxyquinoline; 8 Hydroxyquinoline Sulfate; 8 Hydroxyquinoline; Tendem Brand of Oxyquinoline Sulfate; Superol; Riemser Brand of Oxyquinoline Sulfate; Quinosol; Oxyquinoline Sulfate; Oxyquinoline Potassium Sulfate (2:1); Leioderm; Khinozol; Chinosol Brand of Oxyquinoline Potassium Sulfate (; Chinosol; Bioquin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(177)Lu-oxine-lipiodol  0   *Iodized Oil *Oxyquinoline Radiopharmaceuticals. Cancer Biother Radiopharm. 2010 Oct;25(5):539-43
(166)Ho-oxine-lipiodol  0   *Iodized Oil *Oxyquinoline Radiopharmaceuticals. Nucl Med Commun. 2009 May;30(5):362-7
7-dibromo-2-methyl-8-benzoyloxyquinoline  0   Oxyquinoline/*analogs & derivatives. Boll Chim Farm 2004 Nov;143(9):341-3
8-hydroxy-2-methylquinoline  0   Oxyquinoline/*analogs & derivatives. J Am Chem Soc 2001 May 30;123(21):5160-1
5-(2'-phenyl)azoquinolin-8-ol  0   *Oxyquinoline. Spectrochim Acta A Mol Biomol Spectrosc 2000 Nov 1;56A(12):2453-8
5-(2'-carboxyphenyl)azoquinolin-8-ol  0   *Oxyquinoline. Spectrochim Acta A Mol Biomol Spectrosc 2000 Nov 1;56A(12):2453-8
tris(8-quinolinolato)gallium (III)  0   *Organometallic Compounds Oxyquinoline/*analogs & derivatives Gallium. Anticancer Res 2000 Mar-Apr;20(2A):955-8
5-iodo-8-quinolinol  13207-63-1   Oxyquinoline/*analogs & derivatives. J Pharm Sci 1989;78(11):975
kuprosal  93196-29-3   *Organometallic Compounds *Salicylic Acids *Oxyquinoline Copper. Z Gesamte Hyg 1986;332(6):381
2,8-dihydroxyquinoline  15450-76-7   Oxyquinoline/*analogs & derivatives. Appl Environ Microbiol 1986;51(6):132
bis(8-quinolinolato)copper(II)  10380-28-6   *Organometallic Compounds Oxyquinoline/*analogs & derivatives Copper. Can J Microbiol 1985;31(8):707
technetium Tc 99m 8-hydroxyquinoline  67000-55-9   *Oxyquinoline *Organotechnetium Compounds. Wien Klin Wochenschr 1984;96(3):120
intetrix  87453-65-4 8-Quinolinol, 7-bromo-5-methyl-, mixt. with 5-methyl-8-quinolinol  Drug Combinations Oxyquinoline/*analogs & derivatives. Lancet 1983;1(8326 pt 1):709
tilbroquinol  7175-09-9   Oxyquinoline/*analogs & derivatives. Lancet 1983;1(8326 pt 1):709
8-hydroxyquinoline glucoside  29266-96-4   Oxyquinoline/*analogs & derivatives. C R Soc Biol (Paris) 1982;176(1):39
indium oxine  14514-42-2 Indium-111In, tris(8-quinolinolato-N1,O8)  *Organometallic Compounds Oxyquinoline/*analogs & derivatives Indium Radioisotopes. Br J Hematol 1981;49(2):283INDIUM IN-111 OXYQUINOLINE
5-methyl-8-hydroxyquinoline  5541-67-3   Oxyquinoline/*analogs & derivatives. Mol Pharmacol 1981;20(1):218
Nestosyl ointment  80127-69-1 Benzoic acid, 4-amino-, butyl ester, mixt. with 1,3-benzenediol, ethyl 4-aminobenzoate, 8-quinolinol and zinc oxide (ZnO)  *Oxyquinoline Drug Combinations Benzocaine Morpholines. Contact Dermititis 1981;7(2):120
p-aminosalicylic acid, oxyquinoline drug combination  0   *Aminosalicylic Acid *Oxyquinoline Drug Combinations. Mikroskopie 1980;36(7-8):233
8-hydroxyquinoline-5-sulfonic acid  84-88-8 8-hydroxy-5-quinolinesulfonic acid  Oxyquinoline/*analogs & derivatives. Biochemistry 15(17):3691;1976; Experientia 32(10):1318;1976; Farmaco (Prat) 1979;34(11):503; Radioisotopes 1979;28(11):681
2-(2-hydroxy-5-n-hexylphenyl)-8-quinolinol-4-carboxylic acid  55066-81-4 2-(5-hexyl-2-hydroxyphenyl)-8-hydroxy-4-quinolinecarboxylic acid  Oxyquinoline/*analogs & derivatives. Chem Pharm Bull (Tokyo) 23(1):62;1975
onychofissan tincture  64827-89-0 2-hydroxybenzoic acid compd. with 8-quinolinol mixt. with N,N-bis(2-hydroxyethyl)-10-undecenamide & 2,2'- methylenebis(4-chlorophenol)  *Dichlorophen *Undecylenic Acids *Oxyquinoline Drug Combinations. Mykosen 16(4):137;1973
staphyloimmunocide  79102-49-1 2,4-Imidazolidinedione, 1-((3-(5-nitro-2-furanyl)-2-propenylidene)amino)-, potassium salt, mixt. with 8-quinolinol sulfate (2:1) (salt) and Staphylococcus aureus  *Furagin *Staphylococcus *Oxyquinoline Drug Combinations. Vestn Dermatol Venerol 4:72;1973
quinoderm  78515-96-5 8-Quinolinol, sulfate (1:1) (salt), monopotassium salt, mixt. with dibenzoyl peroxide  *Benzoyl Peroxide *Oxyquinoline Drug Combinations. Practitioner 208(246):541;1972
broxyquinoline  521-74-4 5,7-dibromo-8- hydroxyquinoline  Oxyquinoline/*analogs & derivatives. Acta Path Microbiol Scand 86B(3):155;1978; Contact Dermatitis 1(6):385;1975; Indian J Chest Dis 17(1):8;1975; Int J Dermatol 16(4):267;1977; Lancet 1(8018):956;1977; Lancet 1(8022):1152;1977; Lepr India 1979;51(4):505
Intestopan  8060-82-0 5,7-dibromo-2-methyl-8-quinolinol benzoate (ester) mixt. with 5,7-dibromo-8-quinolinol  *Quinaldines Drug Combinations Oxyquinoline/*analogs & derivatives. Lancet 1(8018):956;1977; Mod Med Asia 14(10):31;1978
5-(n-acetaminophenylazo)-8-oxyquinoline  26424-51-1 5-(p-acetamidophenylazo)-8-hydroxyquinoline  Oxyquinoline/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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