encyclopedia of medical concepts
ψ 
ψ 

9,10-Dimethyl-1,2-benzanthracene

More information in Books or onNLM PubMed
Definition: 7,12-Dimethylbenzanthracene. Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.  a carcinogen; D25-26 qualif; DF: note short X ref   
Pharmacological Action Carcinogens 		Other names 7,12 Dimethylbenzanthracene; DMBA; 7,12-Dimethylbenzanthracene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-hydroxy-7,12-dimethylbenz(a)anthracene  57266-83-8   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Toxicol Appl Pharmacol 1993 Jul;121(1):58-70
6-fluoro-(1,2,3,4-tetrahydro-7,12-dimethylbenz(a)anthracene)  104761-44-6   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Res 1992 Jun 1;52(11):3035-42
5-fluoro-(1,2,3,4-tetrahydro-7,12-dimethylbenz(a)anthracene)  104761-43-5   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Res 1992 Jun 1;52(11):3035-42
7,12-dimethylbenz(a)anthracene-DNA adduct  0   *DNA Adducts 9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1989;10(5):823
3,4-dihydrodiol-1,2-epoxy-9,10-dimethyl-1,2-benzanthracene-deoxyguanosine adduct  0   Deoxyguanosine/*analogs & derivatives 9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Lett 1988;40(3):291
3,4-dihydrodiol-1,2-epoxy 9,10-dimethyl-1,2-benzanthracene deoxyadenosine adduct  0   *Deoxyadenosines 9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Lett 1988;40(3):291
7,12-dimethylbenz(a)anthracene-deoxyadenosine adduct  99745-70-7   *Deoxyadenosines 9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1987;8(3):491
10-fluoro-7,12-dimethylbenz(a)anthracene  71172-13-9   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Res 1985;45(2):591
7,11,12-trimethylbenz(a)anthracene  74845-57-1 Benz(a)anthracene, 7,11,12-trimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Lett 1983;20(2):139
7,12-dimethylbenz(a)anthracene-1,2-dihydrodiol  68984-91-8 Benz(a)anthracene-1,2-diol, 1,2-dihydro-7,12-dimethyl-, trans  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1307
4-methoxy-7,12-dimethylbenz(a)anthracene  16277-49-9   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1221
3-methoxy-7,12-dimethylbenz(a)anthracene  66240-02-6   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1221
2-methoxy-7,12-dimethylbenz(a)anthracene  66240-30-0 Benz(a)anthracene, 2-methoxy-7,12-dimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1221
4-bromo-7,12-dimethylbenz(a)anthracene  78302-39-3 Benz(a)anthracene, 4-bromo-7,12-dimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1221
3-bromo-7,12-dimethylbenz(a)anthracene  78302-38-2 Benz(a)anthracene, 3-bromo-7,12-dimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1221
2-bromo-7,12-dimethylbenz(a)anthracene  78302-37-1 Benz(a)anthracene, 2-bromo-7,12-dimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Carcinogenesis 1983;4(10):1221
7-(hydroxymethyl)-12-methylbenz(a)anthracene sulfate ester  80733-96-6 Benz(a)anthracene-7-methanol, 12-methyl-, hydrogen sulfate  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Science 1982;215(5431):403
1,2,3,4-tetrahydro-7,12-dimethylbenz(a)anthracene  67242-54-0 Benz(a)anthracene, 1,2,3,4-tetrahydro-7,12-dimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Lett 1981;13(2):119
7,12-dimethylbenzanthracene-binding protein, rat  0   *Carrier Proteins 9,10-Dimethyl-1,2-benzanthracene. Chem Biol Interact 1981;37(1-2):55
N(6)-(12-methylbenzanthracenyl-7-methyl)deoxyadenosine  78493-10-4 Adenosine, 2'-deoxy-N-((12-methylbenz(a)anthracen-7-yl)methyl)  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Res 1981;41(6):2230
7,8,12-trimethylbenz(a)anthracene  13345-64-7   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Proc Natl Acad Sci USA 1981;78(2):1185
12-hydroxymethyl-7-methylbenz(a)anthracene  568-70-7 Benz(a)anthracene-12-methanol, 7-methyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Biochem Biophys Res Commun 1980;93(3):782
7,12-dimethylbenz(a)anthracene-10,11-dihydrodiol  72471-79-5 trans-10,11-dihydro-7,12-dimethylbenz(a)anthracene-10,11-diol  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Int J Cancer 24(4):455;1979
7,12-dimethylbenz(a)anthracene-8,9-dihydrodiol  14046-83-4 trans-8,9-dihydro-7,12-dimethylbenz(a)anthracene-8,9-diol  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Int J Cancer 24(4):455;1979
7,12-dimethylbenz(a)anthracene-5,6-dihydrodiol  28622-94-8 trans-5,6-dihydro-7,12-dimethylbenz(a)anthracene-5,6-diol  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Int J Cancer 24(4):455;1979
7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol  72617-60-8 trans-3,4-dihydro-7,12-dimethylbenz(a)anthracene-3,4-diol  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Int J Cancer 24(4):455;1979
3,4-dihydro-3,4-dihydroxy-7,12-dimethylbenz(a)anthracene 1,2-oxide  0   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Chem Biol Interact 1980;29(3):357
3,9-dihydroxy-7,12-dimethylbenz(a)anthracene  0   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. JNCI 62(6):1585;1979
7-hydroxymethyl-12-methylbenz(a)anthracene  568-75-2 12-methylbenz(a)anthracene-7-methanol  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Res 39(4):1154;1979; Chem Biol Interact 1979;27(1):69; Chem Biol Interact 26(2):121;1979
fluoro-7,12-dimethylbenz(a)anthracene  0   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Cancer Res 39(2):411;1979
DMBA endoperoxide  2518-01-6 7,12-Epidioxybenz(a)anthracene, 7,12-dihydro-7,12-dimethyl  9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Int J Cancer 22(3):292;1978
5-fluoro-12-methylbenzanthryl-7-acetic acid  0   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. J Natl Cancer Inst 61(5):1347;1978; Nature 272(5654):614;1978
7,12-dimethylbenz(a)anthracene-dihydrodiol  2518-00-5   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. Biochem Biophys Res Commun 83(4):1468;1978; Br J Cancer 1979;39(5):540; Cancer Res 37(3):775;1977; Proc Natl Acad Sci USA 75(11):5466;1978
7,12-dimethylbenz(a)anthracene 5,6-oxide  39834-38-3   9,10-Dimethyl-1,2-benzanthracene/*analogs & derivatives. J Org Chem 41(21):3487;1976

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy