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Designer Drugs

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Definition: Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.  D25-26 qualif; coord IM with specific drug or chemical (IM); do not confuse with DRUG DESIGN   
See Also Street Drugs; Substance-Related Disorders 		Other names Customized Drugs; Drugs, Designer; Drugs, Customized
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-fluoromethcathinone  0   *Propiophenones Designer Drugs. J Mass Spectrom. 2012 Feb;47(2):253-62.
3-bromomethcathinone  0   *Propiophenones Designer Drugs. J Mass Spectrom. 2012 Feb;47(2):253-62.
3,4-methylenedioxypyrovalerone  0   *Pyrrolidines *Benzodioxoles Psychotropic Drugs Designer Drugs. Drug Test Anal 2010 Aug;2(8):377-82
mephedrone  0   Methamphetamine/*analogs & derivatives Street Drugs Designer Drugs. BMJ. 2010;340() (dup#51):c1605
2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one  0   3,4-Methylenedioxyamphetamine/*analogs & derivatives Designer Drugs. Forensic Sci Int. 2009 Jul 1;188(1-3):131-9
2-ethylamino-1-(3,4-methylenedioxyphenyl)propan-1-one  0   3,4-Methylenedioxyamphetamine/*analogs & derivatives Designer Drugs. Forensic Sci Int. 2009 Jul 1;188(1-3):131-9
1-(4-methylphenyl)-2-pyrrolidin-1-ylhexan-1-one  0   *Pyrrolidines Designer Drugs. J Anal Toxicol 2009 May;33(4):190-7
(1RS,3SR)-3-(4-(1,1-dimethyloctyl)-2-hydroxyphenyl)cyclohexan-1-ol  0   *Cannabinoids Designer Drugs. Chem Pharm Bull (Tokyo). 2009 Apr;57(4):439-41
2-(2,5-dimethoxy-4-isopropylsulfanylphenyl)ethanamine  0   *Phenethylamines Psychoses, Substance-Induced Designer Drugs. Psychiatry Clin Neurosci 2008 Apr;62(2):243
N-(1-phenylcyclohexyl)-2-methoxyethanamine  0   Phencyclidine/*analogs & derivatives Designer Drugs. J Mass Spectrom 2008 Mar;43(3):305-16
N-(1-phenylcyclohexyl)-2-ethoxyethanamine  0   Phencyclidine/*analogs & derivatives Designer Drugs. J Mass Spectrom 2008 Mar;43(3):305-16
4-iodo-2,5-dimethoxy-beta-phenethylamine  0   Dimethoxyphenylethylamine/*analogs & derivatives Designer Drugs. J Mass Spectrom. 2006 Jul;41(7):872-86
alpha-methylfentanyl  79704-88-4   Fentanyl/*analogs & derivatives Street Drugs Designer Drugs. J Psychoact Drugs 1981;13(1):91
2,4,5-trimethoxyphenylisopropylamine  1083-09-6 2,4,5-trimethoxy-alpha-methylbenzeneethanamine  *Amphetamines Designer Drugs. Psychopharmacol Commun 2(3):199;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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