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Calcium Channels

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Definition: Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.  L-, N-, P-, Q-, R-, & T-Type CALCIUM CHANNELS are available; DF: CA CHANNELS   
See Also Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases
Examples Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, T-Type; Inositol 1,4,5-Trisphosphate Receptors; Ryanodine Receptor Calcium Release Channel; TRPP Cation Channels 		Other names VDCC; Receptors, Calcium Channel Blocker; Ion Channels, Calcium; Voltage Dependent Calcium Channels; Channels, Voltage-Dependent Calcium; Calcium Ion Channels; Calcium Ion Channel; Calcium Channels, Voltage-Dependent; Voltage-Dependent Calcium Channels; Receptors, Calcium Channel Antagonist; Ion Channel, Calcium; Calcium Channel Blocker Receptors; Calcium Channel Blocker Receptor; Calcium Channel Antagonist Receptors; Calcium Channel Antagonist Receptor; Calcium Channel
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TARP gamma-4 protein, rat  0   *Calcium Channels Receptors, AMPA. Neuropharmacology. 2011 Dec;61(7):1141-51
TARPgamma-2 protein, rat  0   *Calcium Channels Receptors, AMPA. Neuropharmacology. 2011 Dec;61(7):1141-51
Cch1 protein, S pombe  0   *Calcium Channels *Schizosaccharomyces pombe Proteins. PLoS One 2011;6(7):e22421
CatCh protein, rat  0   *Rhodopsin *Calcium Channels Nerve Tissue Proteins. Nat Neurosci. 2011 Apr;14(4):513-8
stargazin protein, Xenopus  0   *Calcium Channels *Xenopus Proteins. Channels (Austin). 2010 Sep-Oct;4(5):351-4
CACNA2D3 protein, mouse  0   *Calcium Channels. Cell 2010 Nov 12;143(4):628-38
ORAI1 protein, Xenopus  0   *Calcium Channels *Xenopus Proteins. J Cell Biol 2010 Nov 1;191(3):523-35
CACNA1S protein, mouse  0   *Calcium Channels. EMBO J. 2010 Feb 3;29(3):643-54
TPCN2 protein, mouse  0   *Calcium Channels. Pflugers Arch 2009 Sep;458(5):891-9
TPCN1 protein, mouse  0   *Calcium Channels. Pflugers Arch 2009 Sep;458(5):891-9
flower protein, Drosophila  0   *Calcium Channels *Drosophila Proteins. Cell 2009 Sep 4;138(5):947-60
Orai1 protein, rat  0   *Calcium Channels. Hepatology 2008 Oct;48(4):1273-81
STG-2 protein, C elegans  0   *Calcium Channels *Caenorhabditis elegans Proteins. Proc Natl Acad Sci U S A 2006 Jul 11;103(28):10787-92
CACNA2D3 protein, human  0   *Calcium Channels. Gastroenterology 2008 Aug;135(2):580-90
TPCN2 protein, human  0   *Calcium Channels. Nat Genet 2008 Jul;40(7):835-7
CALHM1 protein, human  0   *Membrane Glycoproteins *Calcium Channels. Cell 2008 Jun 27;133(7):1149-61
straightjacket protein, Drosophila  0   *Calcium Channels *Drosophila Proteins. J Cell Biol 2008 Apr 7;181(1):157-70
Cacna1f protein, rat  0   *Calcium Channels. Mol Vis 2001 Aug 22;7:202-9
CACNB4 protein, zebrafish  0   *Calcium Channels *Zebrafish Proteins. Proc Natl Acad Sci U S A 2008 Jan 8;105(1):198-203
Orai3 protein, human  0   *Calcium Channels. J Biol Chem 2007 Jun 15;282(24):17548-56
Cacng4 protein, rat  0   *Calcium Channels. J Neurosci 2007 Aug 1;27(31):8442-7
CACNG8 protein, human  0   *Calcium Channels.
CACNG6 protein, human  0   *Calcium Channels.
CACNG5 protein, human  0   *Calcium Channels.
CACNG4 protein, human  0   *Calcium Channels.
CACNG1 protein, human  0   *Calcium Channels.
CACNG3 protein, human  0   *Calcium Channels Nerve Tissue Proteins. Eur J Hum Genet 2007 Apr;15(4):463-72
Orai3 protein, mouse  0   *Calcium Channels. Biochem Biophys Res Commun 2007 Apr 27;356(1):45-52
Orai2 protein, mouse  0   *Calcium Channels. Biochem Biophys Res Commun 2007 Apr 27;356(1):45-52
Orai1 protein, mouse  0   *Calcium Channels. Biochem Biophys Res Commun 2007 Apr 27;356(1):45-52
MCA1 protein, Arabidopsis  0   *Membrane Proteins *Arabidopsis Proteins Calcium Channels. Proc Natl Acad Sci U S A 2007 Feb 27;104(9):3639-44
NALCN protein, mouse  0   *Ion Channels *Nerve Tissue Proteins Calcium Channels Potassium Channels. Cell 2007 Apr 20;129(2):371-83
ORAI-1 protein, C elegans  0   *Calcium Channels *Caenorhabditis elegans Proteins. J Physiol 2007 Apr 1;580(Pt 1):67-85
STG-1 protein, C elegans  0   *Calcium Channels *Caenorhabditis elegans Proteins Nerve Tissue Proteins. Proc Natl Acad Sci U S A 2006 Jul 11;103(28):10781-6
CACNA2D1 protein, mouse  0   *Calcium Channels. Brain Res 2006 Feb 23;1075(1):68-80
ORAI1 protein, human  0   *Calcium Channels. Nature 2006 May 11;441(7090):163-5
Cacnb3 protein, mouse  0   *Calcium Channels. Biol Pharm Bull 2006 Mar;29(3):437-42
Cacng4 protein, mouse  0   *Calcium Channels. Proc Natl Acad Sci U S A 2005 Feb 8;102(6):2123-8
TPC1 protein, Arabidopsis  0   *Calcium Channels *Arabidopsis Proteins. Nature. 2005 Mar 17;434(7031):404-8
voltage gated calcium channel subunit Ca alpha2delta-1, human  0   *Calcium Channels. Bioorg Med Chem Lett. 2004 May 17;14(10):2463-7
Ecac1 protein, rat  0   *Calcium Channels *TRPV Cation Channels.
Trpv5 protein, mouse  0   *Calcium Channels *TRPV Cation Channels.
CACNG2 protein, human  0   *Calcium Channels.
Cacng2 protein, rat  0   *Calcium Channels.
Cacnb4 protein, mouse  0   *Calcium Channels.
Cacnb4 protein, rat  0   *Calcium Channels.
Cacna1a protein, rat  0   *Calcium Channels Cerebellar Ataxia Migraine with Aura.
Catsper1 protein, mouse  0   *Calcium Channels. Hum Reprod. 2004 Jan;19(1):124-8
Pkd2l1 protein, mouse  0   *Receptors, Cell Surface *Calcium Channels.
Cacna2d1 protein, rat  0   *Calcium Channels.
Cacna2d2 protein, mouse  0   *Calcium Channels.
Trpv2 protein, mouse  0   *Calcium Channels *TRPV Cation Channels.
Scamper protein, rat  0   *Calcium Channels.
Cacnb3 protein, rat  0   *Calcium Channels.
CACNA2D2 protein, human  0   *Calcium Channels. Neurology 2003 May 27;60(10):1631-7
Cacna1f protein, mouse  0   *Calcium Channels. Genomics 2000 Jun 15;66(3):324-7
CatSper2 protein, mouse  0   *Calcium Channels *Seminal Plasma Proteins. Proc Natl Acad Sci U S A 2003 Dec 9;100(25):14869-74
Cacna2d3 protein, rat  0   *Calcium Channels. J Mol Cell Cardiol 2003 Feb;35(2):207-15
Cacna2d2 protein, rat  0   *Calcium Channels. J Mol Cell Cardiol 2003 Feb;35(2):207-15
trp-3 protein, C elegans  0   *Calcium Channels *Caenorhabditis elegans Proteins. Cell. 2003 Aug 8;114(3):285-97
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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