encyclopedia of medical concepts
ψ
ψ
ψ
Idarubicin
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Definition
: An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Pharmacological Action
Antibiotics, Antineoplastic
Other names
4-
Demethoxydaunorubicin; NSC256439; NSC 256439; IMI30; Hydrochloride, Idarubicin; 4 Desmethoxydaunorubicin; 4 Demethoxydaunorubicin; IMI 30; NSC-
256439; Idarubicin Hydrochloride; 4-
Desmethoxydaunorubicin; IMI-
30
Drugs
*
:
IDARUBICIN HYDROCHLORIDE
;
IDAMYCIN
;
IDAMYCIN PFS
;
IDARUBICIN HYDROCHLORIDE PFS
Substance
CAS Registry & name
Categories
Source
Drugs
*
EORTC GIMEMA AML-
13 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Mitoxantrone
Idarubicin.
Haematologica 2007 May;92(5):605-11
EORTC GIMEMA AML-
10 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Daunorubicin
Etoposide
Mitoxantrone
Idarubicin.
Haematologica 2007 May;92(5):605-11
MATILDE regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Methotrexate
Thiotepa
Idarubicin.
Neurology 2006 May 9;66(9):1435-8
8-
hydroxy-
8-
methylidarubicinone
0
Idarubicin/*analogs & derivatives.
Bioorg Med Chem. 2004 Jun 1;12(11):2863-6
TCID protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Dexamethasone
Thalidomide
Idarubicin.
Ann Hematol 2004 Jul;83(7):467-70
VID protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Vincristine
Idarubicin.
Ann Hematol 2004 Jul;83(7):467-70
ICBV regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Carmustine
Cyclophosphamide
Etoposide
Idarubicin.
Int J Hematol 2004 Jan;79(1):85-91
CIOD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Dexamethasone
Vincristine
Idarubicin.
Ann Oncol l2003 Dec;14(12):1792-4
idarubicinone
0
Idarubicin/*analogs & derivatives.
J Org Chem 2003 Mar 21;68(6):2398-404
DIZE protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Etoposide/analogs & derivatives
Ifosfamide
Idarubicin.
Leuk Lymphoma 1999 Nov;35(5-6):641-2
FLU-
ID regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Vidarabine/analogs & derivatives
Idarubicin.
Haematologica 1999 Nov;84(11):1002-6
Ida-
FLAG protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Vidarabine/*analogs & derivatives
Idarubicin
Granulocyte Colony-Stimulating Factor.
Ann Hematol 1999 Sep;78(9):418-25
GIMEMA ALL 0394
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Idarubicin.
Haematologica 1999 Mar;84(3):222-5
VICED protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Etoposide
Vincristine
Idarubicin.
Leuk Lymphoma 1998 Jun;30(1-2):153-62
CIOP-
Bleo protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Prednisone
Vincristine
Idarubicin.
Anticancer Drugs 1997 Nov;8(10):937-42
MIZE protocol
0
Mesna
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Ifosfamide
Idarubicin.
Leuk Lymphoma 1997 Aug;26(5-6):595-602
FLIDA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Prednisone
Vidarabine/analogs & derivatives
Idarubicin.
Henatol Oncol 1997 Feb;15(1):27-31
VICOP-
B protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Etoposide
Prednisone
Vincristine
Idarubicin.
Haematologica 1997 May-Jun;82(3):309-13
AIDA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Tretinoin
Idarubicin.
Blood 1997 Aug 1;90(3):1014-21
IIVP-
16
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Ifosfamide
Idarubicin.
Leuk Lymphoma 1997 Feb;24(5-6):513-22
CIP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Prednisone
Idarubicin.
Leuk Lymphoma 1997 Jan;24(3-4):355-61
8-
fluoroidarubicin
0
Idarubicin/analogs & derivatives.
Mol Pharmacol 1996 Mar;49(3):532-9
IVAP protocol
0
Asparaginase
*Antineoplastic Combined Chemotherapy Protocols
Prednisolone
Vincristine
Idarubicin.
Semin Oncol 1993 Dec;20(6 Suppl 8):39-46
ETI protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Thioguanine
Idarubicin.
Leukemia 1994 Jan;8(1):11-5
ICE protocol 4
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Idarubicin.
Bone Marrow Transplant 1993 Sep;12(3):267-71
LAI regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Idarubicin.
Hematol Oncol 1993 Mar-Apr;11(2):73-80
CIOP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Prednisolone
Vincristine
Idarubicin.
Leuk Lymphoma 1993;10 Suppl:39-41
4-
demethoxydaunomycinone
60660-75-5 5,12-
Naphthacenedione, 9-
acetyl-
7,8,9,10-
tetrahydro-
6,7,9,11-
tetrahydroxy-
, (7S-
cis)
Idarubicin/*analogs & derivatives.
Cancer Chemother Pharmacol 1992;30(4):303-6
ALL-
1 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Asparaginase
Cyclophosphamide
Prednisone
Vincristine
Idarubicin.
Semin Hematol 1991 Jul;28(3 Suppl 4):72-5
13-
methyl-
13-
dihydro-
4-
demethoxydaunorubicin
111248-05-6
Idarubicin/*analogs & derivatives.
Chem Pharm Bull (Tokyo) 1986;34(11):4613
9-
O-
daunosaminyl-
4-
demethoxydaunorubicin
99457-12-2
Idarubicin/*analogs & derivatives.
J Antibiot (Tokyo) 1985;38(9):1277
4-
demethoxy-
10,10-
dimethyldaunomycin
91003-74-6
Idarubicin/*analogs & derivatives.
J Med Chem 1984;27(10):1343
4-
demethoxydaunorubicin bis(hydrazone)
77313-12-3 Pentanedioic acid, 3-
amino-
, bis((1-
(4-
((3-
amino-
2,3,6-
trideoxy-
alpha-
L-
lyxo-
hexopyranosyl)oxy)-
1,2,3,4,6,11-
hexahydro-
2,5,12-
trihydroxy-
6,11-
dioxo-
2-
naphthacenyl)ethylidene)hydrazide), trihydrochloride, (2S-
(2alpha,2(2R*,4R*),4alpha))
Idarubicin/*analogs & derivatives.
Cancer Res 1983;43(6):2880
4-
demethoxy-
11-
deoxydaunomycin
77312-66-4 5,12-
Naphthacenedione, 9-
acetyl-
7-
((3-
amino-
2,3,6-
trideoxy-
alpha-
L-
lyxo-
hexopyranosyl)oxy)-
7,8,9,10-
tetrahydro-
6,9-
dihydroxy-
, (7S-
cis)
Idarubicin/*analogs & derivatives.
J Antibiot (Tokyo)1980;33(12):1581