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Biological Markers

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Definition: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.  IM general only; coordinate NIM with specific substance (IM); note that many specific markers are available; DF: BIOL MARKERS   
See Also Endophenotypes; Molecular Probes
Examples Antibodies, Antineutrophil Cytoplasmic; Antigens, Differentiation; Biomarkers, Pharmacological; Chorionic Gonadotropin, beta Subunit, Human; Fibrinopeptide A; Genetic Markers; Oligoclonal Bands; Tumor Markers, Biological 		Other names Viral Markers; Surrogate Markers; Serum Markers; Markers, Viral; Markers, Surrogate; Markers, Serum; Markers, Laboratory; Markers, Immunologic; Markers, Clinical; Markers, Biological; Markers, Biochemical; Laboratory Markers; Immunologic Markers; Clinical Markers; Biochemical Markers; Markers, Immune; Markers, Biologic; Marker, Viral; Marker, Immune; Marker, Biologic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Axin2 protein, rat  0   *Carrier Proteins Biological Markers. Genomics. 1999 Feb 1;55(3):341-4.
Pcp-2 protein, rat  0   *Nerve Tissue Proteins Biological Markers. Biol Trace Elem Res. 2011 Dec;143(3):1629-39.
PRG-3 protein, rat  EC 3.1.3.-   *Phosphoric Monoester Hydrolases Nerve Tissue Proteins Biological Markers. Eur J Neurosci. 2004 Jan;19(1):212-20.
villin1 protein, human  0   *Microfilament Proteins Biological Markers. Clin Chem. 2006 Mar;52(3):520-3.
TIM-3 protein, rat  0   *Receptors, Cell Surface Biological Markers. Nature. 2002 Jan 31;415(6871):536-41.
L1TD1 protein, human  0   *Proteins Biological Markers. PLoS One 2011;6(4):e19355
BAD-LAMP protein, human  0   *Membrane Proteins Biological Markers. Blood 2011 Jul 21;118(3):609-17
Se-methylselenoneine  0   *Organoselenium Compounds Histidine/*analogs & derivatives Biological Markers. Metallomics 2011 May 1;3(5):513-20
ischemia-modified albumin  0   *Serum Albumin Biological Markers Myocardial Ischemia/diagnosis.
N2-(4-hydroxyphenyl)guanine  0   Guanine/*analogs & derivatives DNA Adducts Biological Markers. Toxicol Lett 2011 Sep 10;205(3):273-8
1-deoxymethylsphinganine  0   Sphingosine/*analogs & derivatives Biological Markers. Hum Mutat 2011 Jun;32(6):E2211-25
1-deoxysphinganine  0   Sphingosine/*analogs & derivatives Biological Markers. Hum Mutat 2011 Jun;32(6):E2211-25
3,5-dihydroxycholest-7-en-6-one  0   *Cholestenones Biological Markers. J Lipid Res 2011 Jun;52(6):1222-33
mab-3-related transcription factor 5, mouse  0   *Transcription Factors Biological Markers. Proc Natl Acad Sci U S A 2011 May 31;108(22):9131-6
MIRN194 microRNA, human  0   *MicroRNAs Biological Markers. Hepatology 2010 Dec;52(6):2148-57
MIRN194 microRNA, mouse  0   *MicroRNAs Biological Markers. Hepatology 2010 Dec;52(6):2148-57
Tmem123 protein, mouse  0   *Membrane Proteins Biological Markers. J Biol Chem 2010 Oct 8;285(41):31876-84
gSG6-P1 peptide, human  0   *Salivary Proteins and Peptides Biological Markers. Trop Med Int Health. 2010 Oct;15(10):1198-203
midregional pro-atrial natriuretic peptide, human  0   *Atrial Natriuretic Factor Biological Markers Stroke. J Am Coll Cardiol. 2010 Sep 21;56(13):1045-53
Grhl1 protein, zebrafish  0   *Zebrafish Proteins Biological Markers. Int J Dev Biol 2010;54(5):837-50
accA3 protein, Mycobacterium leprae  0   *Bacterial Proteins Biological Markers. Indian J Lepr. 2009 Jul-Sep;81(3):141-8
TM9SF4 protein, human  0   *Membrane Proteins Neoplasm Proteins Biological Markers. EMBO Rep 2009 Dec;10(12):1348-54
Cocoacrisp protein, rat  0   *Proteins Biological Markers. Biomarkers. 2009 Sep;14(6):366-71
TROP2 protein, mouse  0   *Antigens, Neoplasm *Cell Adhesion Molecules Biological Markers. Development 2009 Jun;116(11):1951-60
collagen II C-telopeptide  0   *Peptide Fragments *Collagen Type II Biological Markers. Clin Exp Rheumatol. 2009 Mar-Apr;27(2); 307-14
1-(6-deoxy-6-iodogalactopyranosyl)-2-nitroimidazole  0   *Galactosides *Nitroimidazoles Biological Markers. Nucl Med Biol 2009 Jul;36(5):477-87
MIRN375 microRNA, human  0   *MicroRNAs Biological Markers. Clin Cancer Res 2009 Apr 15;15(8):2850-5
butyl-2-methyl-malonic acid  0   Methylmalonic Acid/*analogs & derivatives Biological Markers. Apoptosis 2009 Mar;14(3):257-67
Mirn192 microRNA, mouse  0   *MicroRNAs Biological Markers. Proc Natl Acad Sci U S A 2009 Mar 17;106(11):4402-7
methyl 4-anisate  0   *Benzoates Biological Markers. Tuberculosis (Edinb) 2008 Jul;88(4):317-23
prolyl-4-hydroxyproline  0   *Dipeptides Proline Biological Markers. Clin Chem Lab Med 2008;46(10):1391-7
TMEM16A protein, mouse  0   *Chloride Channels Biological Markers. Dev Biol 2008 Sep 1;321(1):141-9
CG32663 protein, Drosophila  0   *Drosophila Proteins Biological Markers. Exp Cell Res 2008 May 1;314(8):1804-10
glycogen phosphorylase BB, human  EC 2.4.1.-   *Glycogen Phosphorylase Biological Markers. Vnitr Lek 2007 Nov;53(11):1164-9
xP1-L protein, Xenopus  0   *Xenopus Proteins Biological Markers. Gene Expr Patterns 2007 Dec;8(1):12-8
Plet-1 protein, human  0   *Pregnancy Proteins Biological Markers. Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):961-6
Plet-1 protein, mouse  0   *Pregnancy Proteins Biological Markers. Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):961-6
Opalin protein, human  0   *Myelin Proteins Biological Markers. J Neurochem 2007 Sep;102(5):1533-47
Opalin protein, mouse  0   *Myelin Proteins Oligodendroglia Biological Markers. J Neurochem 2007 Sep;102(5):1533-47
LF22 peptide, Limnoperna fortunei  0   *Peptides Biological Markers. Environ Pollut 2006 Nov;144(1):280-8
meconin  0   Noscapine/*analogs & derivatives Biological Markers/urine. Anal Toxicol 2007 Mar;31(2):105-8
Wdr16 protein, zebrafish  0   *Microfilament Proteins *Zebrafish Proteins Biological Markers. J Neurochem 2007 Apr;101(1):274-88
disialotransferrin  0   *Sialoglycoproteins Transferrin/*analogs & derivatives Biological Markers. Arch Dis Child 1989 Jan;64(1):71-6
K75 protein, mouse  0   *Keratins, Hair-Specific Biological Markers. J Invest Dermatol 2007 May;127(5):
SERPINA3 protein, human  0   *Serpins Biological Markers. Hypertension 2007 Jan;49(1):76-83
OXPAT protein, mouse  0   *Intracellular Signaling Peptides and Proteins Biological Markers. Diabetes 2006 Dec;55(12):3418-28
Noxp70 protein, mouse  0   *Carrier Proteins *Nerve Tissue Proteins Biological Markers Zinc Fingers. J Neurochem 2006 Oct;99(2):657-69
Noxp20 protein, mouse  0   *Nerve Tissue Proteins Biological Markers. J Neurochem 2006 Oct;99(2):657-69
Rex-1 protein, mouse  0   *Transcription Factors Biological Markers. Mol Cell Biol 1989 Dec;9(12):5623-9
precoproporphyrin  0   *Porphyrins Biological Markers. Toxicol Appl Pharmacol 2006 Jul 15;214(2):99-108
Pap31 protein, Bartonella bacilliformis  0   *Antigens, Bacterial Biological Markers. Ann N Y Acad Sci 2005 Dec;1063:280-5
capucin protein, mouse  0   *Membrane Proteins Biological Markers. Genomics 2006 Feb;87(2):200-7
methylenediphenyl diisocyanate-glutathione adduct  0   *Benzhydryl Compounds Glutathione/*analogs & derivatives Biological Markers. Toxicology 2006 May 15;222(3):202-12
VGF protein, human  0   *Nerve Growth Factors Cerebrospinal Fluid Proteins Biological Markers. Genomics 1997 Oct 15;45(2):443-6
K6HF protein, human  0   *Keratins, Type II *Keratins, Hair-Specific Biological Markers. Physiol Genomics 2004 Oct 4;19(2):207-17
MT-10.3 protein, Mycobacterium  0   *Antigens, Bacterial *Bacterial Proteins Biological Markers. Int J Tuberc Lung Dis. 2005 Apr;9(4):461-6
Lman1 protein, rat  0   *Membrane Proteins *Mannose-Binding Lectins Biological Markers.
TPH1 protein, human  EC 1.14.16.4   *Tryptophan Hydroxylase Biological Markers. Genes Brain Behav. 2004 Dec;3(6):328-36
BM88 protein, mouse  0   *Membrane Proteins *Nerve Tissue Proteins Biological Markers. Eur J Neurosci 2004 Nov;20(10):2509-23
BM88 protein, rat  0   *Membrane Proteins *Nerve Tissue Proteins Biological Markers. Eur J Neurosci 2004 Nov;20(10):2509-23
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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