encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 
ψ 
ψ 
ψ 

Lambert-Eaton Myasthenic Syndrome

More information in Books or onNLM PubMed
Definition: An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)      Other names Myasthenic Syndrome, Lambert-Eaton; Eaton-Lambert Syndrome; Syndrome, Lambert-Eaton Myasthenic; Syndrome, Lambert-Eaton; Syndrome, Eaton-Lambert Myasthenic; Syndrome, Eaton-Lambert; Myopathic Myasthenic Syndrome of Eaton Lambert; Myasthenic Syndrome, Lambert Eaton; Myasthenic Syndrome, Eaton-Lambert; Myasthenic Myopathic Syndrome of Lambert Eaton; Myasthenic Myopathic Syndrome of Eaton Lambert; Lambert-Eaton Myopathic-Myasthenic Syndromes; Lambert-Eaton Myopathic-Myasthenic Syndrome; Lambert-Eaton Myasthenic-Myopathic Syndromes; Lambert-Eaton Myasthenic-Myopathic Syndrome; Lambert Eaton Myasthenic Syndrome; Eaton-Lambert Myopathic-Myasthenic Syndromes; Eaton-Lambert Myopathic-Myasthenic Syndrome; Lambert Eaton Syndrome; Eaton-Lambert Myasthenic-Myopathic Syndrome

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify.
We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy