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2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine

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Definition: A selective D1 dopamine receptor agonist used primarily as a research tool.     
Pharmacological Action Dopamine Agonists
Other names SKF 38393A; SKF 38393 A; SKF 38393; SK&F38393; SK&F 38393; RSK&F 38393; SKF38393; SKF-38393; SKF 38393-A; SK&F-38393; 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-ph; R-SK&F 38393
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SK&F 83959  80751-85-5   2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*analogs & derivatives. Eur J Pharmacol 1993 Mar 30;234(1):135-6
3-allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine  135974-57-1   2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*analogs & derivatives. J Med Chem 1991;34(12):3366
SK&F 77434  104422-04-0   2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*analogs & derivatives. Eur J Pharmacol 1990;186(1):79
SK&F R87516  72912-26-6   2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*analogs & derivatives. Eur J Pharmacol 1986;126(1-2):167
SK&F 83566  94344-79-3   2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*analogs & derivatives.
Pharma Action Dopamine Antagonists
Eur J Pharmacol 1984;106(1):219
trimopam  20012-08-2 1H-3-benzazepine, 2,3,4,5-tetrahydro-7,8-dimethoxy-3-methyl-1-phenyl-, (+)  2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/*analogs & derivatives. Curr Ther Res 13(11):714;1971; Curr Ther Res 21(1):70;1977; J Chromatogr 1979;163(1):47; Psychopharmacologia 36:281;1974; Psychopharmacologia 48(1):79;1976; Psychopharmacology 59(2):189;1978; Union Med Can 104(6):904;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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