Definition: Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 188.8.131.52.
coord with specific virus
Other names v-ras, p21; v-Ki-ras, p21; v-Ha-ras, p21; v-H-ras, p21; p21 v ras; p21 v Ki ras; p21 v Ha ras; ras Oncogene Protein p21; p21(v-Ki-ras); p21(v-Ha-ras); p21 v H ras; ras Oncogene p21 Product; ras Oncogene Product p21; p21(v-K-ras); p21(v-H-ras); p21 v-ras; p21 v-Ki-ras; p21 v-Ha-ras; p21 v-H-ras; p21 Transforming Viral Protein