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HIV Envelope Protein gp120

More information in Books or onNLM PubMed
Definition: External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.     
See Also Peptide T
Other names gp120, HTLV-III; HTLV III gp120; gp120(HIV); env Protein gp120, HIV; HTLV-III gp120; Envelope Glycoprotein gp120, HIV; gp120 Envelope Glycoprotein, HIV; HIV Envelope Glycoprotein gp120
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
gp120 protein, Human immunodeficiency virus 2  0   *HIV Envelope Protein gp120.
gp120 protein, Human immunodeficiency virus 1  0   *HIV Envelope Protein gp120.
N-(4-chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide  0   *Oxalates *Piperidines HIV Envelope Protein gp120. Biochemistry 2006 Sep 12;45(36):10973-80
HIV envelope protein gp120 (254-274)  0   *HIV Envelope Protein gp120 *Peptide Fragments. J Pept Sci 2004 Jun;10(6):363-80
P18-I10 peptide  0   *Peptide Fragments *HIV Envelope Protein gp120 Epitopes. Biochem Biophys Res Commun 2004 Apr 2;316(2):356-63
HIV envelope protein gp120 (421-436)  0   *Peptide Fragments *HIV Envelope Protein gp120. Vaccine 2003 Mar 7;21(11-12):1213-8
HKR peptide  0   *Oligopeptides HIV Envelope Protein gp120. Cell Immunol 2001 May 25;210(1):49-55
CLIV peptide  0   *Peptide Fragments *HIV Envelope Protein gp120. Virology. 2000 Jul 20;273(1):169-77
MNrgp120 vaccine  0   *HIV Envelope Protein gp120 *AIDS Vaccines. J Infect Dis 1999 Oct;180(4):1080-8
HIV-1 peptomer (419-436)  0   *Peptide Fragments *HIV Envelope Protein gp120. Peptides 1999;20(2):159-63
RP142 peptide  0   *Peptide Fragments *HIV Envelope Protein gp120. J Biomol Struct Dyn 1999 Feb;16(4):931-53
AIDSVAX  0   *AIDS Vaccines HIV Envelope Protein gp120. Science 1998 Jun 12;280(5370):1697
B1M-P3C protein, recombinant  0   *Peptide Fragments *Recombinant Proteins *HIV Envelope Protein gp120 Lipoproteins. Dev Biol Stand 1998;92:109-16
glycyl-prolyl-glycyl-arginyl-alanyl-phenylanine  0   *Peptide Fragments *HIV Envelope Protein gp120. Mol Biol (Mosk) 1997 Sep-Oct;31(5):872-9
KAB 121  0   *Diglycerides *HIV Envelope Protein gp120. Biol Pharm Bull 1996 Oct;19(10):1271-4
RP 135 peptide  0   *Peptide Fragments *HIV Envelope Protein gp120. Eur J Biochem 1995 Apr 1;229(1):178-87
HIV-1 immunogen, incomplete Freund's adjuvant  0   *AIDS Vaccines Freund's Adjuvant HIV Envelope Protein gp120. J Acquir Immune Defic Syndr Hum Retrovirol 1996 Apr 1;11(4):351-64
RP342 peptide  0   *Peptide Fragments *HIV Envelope Protein gp120. Dokl Akad Nauk 1995 Oct;344(4):546-8
SPC3 peptide  0   *Recombinant Proteins *HIV Envelope Protein gp120. In Vitro Cell Dev Biol Anim 1995 Jun;31(6):415-8
RP70 peptide  0   *Peptide Fragments *HIV Envelope Protein gp120. Dokl Akad Nauk 1995 Jun;342(4):543-5
PPD-MN-PND vaccine  0   *HIV Envelope Protein gp120 Tuberculin AIDS Vaccines. AIDS 1995 Mar;9(3):243-51
HIV envelope protein gp120 (302-324)  0   *Peptide Fragments *HIV Envelope Protein gp120. Protein Eng 1994 Apr;7(4):509-14
HIV-1 IIIB gp120 subunit vaccine  0   *HIV Envelope Protein gp120 *AIDS Vaccines Vaccines, Synthetic. Lancet 1993 Jul 10;342(8863):69-73
HIV envelope protein gp120 (305-321)  0   *Peptide Fragments *HIV Envelope Protein gp120 HIV-1 HIV-2. J Acquir Immune Defic Syndr 1989;2(3):303
HIV envelope protein gp120 (135-148)  0   *Peptide Fragments *HIV Envelope Protein gp120 HIV-1. J Acquir Immune Defic Syndr 1989;2(3):303
HIV envelope protein gp120 (55-65)  0   *Peptide Fragments *HIV Envelope Protein gp120 HIV-1. J Acquir Immune Defic Syndr 1989;2(3):303

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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