encyclopedia of medical concepts
ψ 
ψ 
ψ 

5'-Nucleotidase

More information in Books or onNLM PubMed
Definition: A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.      Other names Uridylate 5'-Nucleotidase; Thymidine Phosphatase; Pyrimidine 5'-Nucleotidase; Inosinate Phosphatase; IMP Phosphatase; IMP Nucleotidase; Ecto-5'-Nucleotidase; Cytidylate Phosphatase; CD73 Antigens; Antigens, CD73; Adenylate Phosphatase; AMP Phosphatase; 5'-AMP Nucleotidase; Uridylate 5' Nucleotidase; Pyrimidine 5' Nucleotidase; Ecto 5' Nucleotidase; CD73 Antigen; 5' Nucleotidase Phosphoribolase; 5' Nucleotidase; 5' AMP Nucleotidase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NT5M protein, human  EC 3.1.3.5   *5'-Nucleotidase.
NT5C1A protein, human  EC 3.1.3.5   *5'-Nucleotidase.
NT5C1B protein, human  EC 3.1.3.5   *5'-Nucleotidase.
Nt5e protein, rat  EC 3.1.3.5   *5'-Nucleotidase GPI-Linked Proteins.
Nt5e protein, mouse  EC 3.1.3.5   *5'-Nucleotidase GPI-Linked Proteins.
NT5E protein, human  EC 3.1.3.5   *5'-Nucleotidase GPI-Linked Proteins.
5-Nucleotidase syndrome  0   *Metabolism, Inborn Errors 5'-Nucleotidase/deficiency.
alpha,beta-methyleneadenosine 5'-diphosphate  0   Adenosine Diphosphate/*analogs & derivatives 5'-Nucleotidase/antagonists & inhibitors. Biochim Biophys Acta 2007 Sep;1770(9):1352-9
NT5C2 protein, human  EC 3.1.3.5   *5'-Nucleotidase. Lung Cancer 2005 Sep;49(3):363-70
Nt5c3 protein, mouse  EC 3.1.3.5   *5'-Nucleotidase.
SDT1 protein, S cerevisiae  EC 3.1.3.5   *5'-Nucleotidase *Saccharomyces cerevisiae Proteins.
NT5C3 protein, human  EC 3.1.3.5   *Glycoproteins *5'-Nucleotidase. Blood 2000 Aug 15;96(4):1596-8
NF 86II  123997-73-9   *Biopolymers *Phenols 5'-Nucleotidase/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1992 Mar;40(3):802-4
5'(3')-nucleotidase  EC 3.1.3.-   *5'-Nucleotidase. J Biol Chem 1990;265(12):6589
nucleoticidin  96081-70-8 Nucleoticidin  *Polysaccharides 5'-Nucleotidase/antagonists & inhibitors. J Antibiot (Tokyo) 1985;38(11):1564
melanocidin B  97162-51-1 Melanocidin B  *Polysaccharides 5'-Nucleotidase/antagonists & inhibitors. J Antibiot (Tokyo) 1985;38(5):587
melanocidin A  97162-50-0 Melanocidin A  *Polysaccharides 5'-Nucleotidase/antagonists & inhibitors. J Antibiot (Tokyo) 1985;38(5):587
adenosine 5'-methylenediphosphate  3768-14-7 adenosine, 5'-(trihydrogen methylenebis(phosphonate))  Adenosine Diphosphate/*analogs & derivatives 5'-Nucleotidase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Can J Physiol Pharmacol 54(4):626;1976; FEBS Lett 1980;110(1):30; J Pharmacol Exp Ther 1979;211(3):525; Proc Nat Acad Sci USA 71(1):205;1974; Recent Adv Stud Cardiac Struct Metab 10:584;1975

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy