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Calcitonin Gene-Related Peptide

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Definition: Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.  DF: CGRP   
Pharmacological Action Vasodilator Agents
See Also Receptors, Calcitonin Gene-Related Peptide 		Other names beta CGRP; alpha CGRP; Peptide, Calcitonin Gene-Related; Gene-Related Peptide, Calcitonin; Calcitonin Gene Related Peptide II; Calcitonin Gene Related Peptide I; Calcitonin Gene Related Peptide; beta-CGRP; alpha-CGRP; Calcitonin Gene-Related Peptide II; Calcitonin Gene-Related Peptide I
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
alpha-calcitonin gene-related peptide, ethylamide-Cys(2,7)  0   Calcitonin Gene-Related Peptide/*analogs & derivatives Receptors, Calcitonin Gene-Related Peptide/antagonists & inhibitors. Life Sci 2006 Jun 13;79(3):265-71
calcitonin gene-related peptide (8-37), propionyllysyl(24)  0   *Peptide Fragments *Calcitonin Gene-Related Peptide Tritium. J Med Chem 2006 Jan 26;49(2):616-24
calcitonin gene-related peptide (27-37):  0   *Calcitonin Gene-Related Peptide. Regul Pept 2001 Sep 15;101(1-3):101-8
BIBN 4096BS  0   *Piperazines *Quinazolines Calcitonin Gene-Related Peptide/analogs & derivatives. Br J Pharmacol 2000 Feb;129(3):420-3
calcitonin gene-related peptide, (acetylmethoxy)cysteinyl(2,7)  0   Calcitonin Gene-Related Peptide/*analogs & derivatives Receptors, Calcitonin Gene-Related Peptide/agonists. Eur J Pharmacol 1999 Dec 3;385(2-3):147-54
calcitonin gene related peptide (1-7)  0   *Peptide Fragments *Calcitonin Gene-Related Peptide. J Neurosci 1999 Apr 15;19(8):2945-53
calcitonin gene related peptide (32-37)  0   *Peptide Fragments *Calcitonin Gene-Related Peptide. Regul Pept 1993 Nov 19;49(1):73-80
calcitonin gene related peptide (19-37)  0   *Peptide Fragments *Calcitonin Gene-Related Peptide. Peptides 1992 Sep-Oct;13(5):1025-7
calcitonin gene-related peptide (23-37)  0   *Peptide Fragments *Calcitonin Gene-Related Peptide. Peptides 1992 Sep-Oct;13(5):1025-7
preprocalcitonin gene-related peptide  0   *Protein Precursors *Calcitonin Gene-Related Peptide. Brain Res 1992 Apr 3;576(2):287-96
pro-calcitonin gene-related peptide  95077-07-9 Calcitonin gene-related peptide, pro  *Protein Precursors *Calcitonin Gene-Related Peptide. Ann N Y Acad Sci 1992 Jun 30;657:50-62
calcitonin gene-related peptide (19-37), t-butyl-Cys(18)  137908-73-7   *Peptide Fragments Calcitonin Gene-Related Peptide/*analogs & derivatives. Biochem J 1991 Nov 15;280(Pt 1):147-50
calcitonin gene-related peptide (28-37)  0   *Peptide Fragments *Calcitonin Gene-Related Peptide. Eur J Pharmacol 1991;199(3):375
calcitonin gene-related peptide (8-37)  119911-68-1   *Peptide Fragments *Calcitonin Gene-Related Peptide Receptors, Calcitonin Gene-Related Peptide/antagonists & inhibitors.
Pharma Action Miotics 		Am J Physiol 1989;256(2 Pt 1):E331
calcitonin gene-related peptide, Asu(2,7)  108568-91-8   *Peptide Fragments *Calcitonin Gene-Related Peptide. Experientia 1987;43(8):890

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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