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Cell Adhesion Molecules, Neuronal

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Definition: Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection of the vertebrate nervous system. These molecules promote cell adhesion via a homophilic mechanism. These are not to be confused with NEURAL CELL ADHESION MOLECULES, now known to be expressed in a variety of tissues and cell types in addition to nervous tissue.  do not confuse with CELL ADHESION MOLECULES, NEURON-GLIA; do not confuse X ref NEURONAL CELL ADHESION MOLECULES with NCAM for X ref NEURAL CELL ADHESION MOLECULE   
Examples Cell Adhesion Molecules, Neuron-Glia; Contactins; Myelin P0 Protein; Neural Cell Adhesion Molecules 		Other names Neuronal Cell Adhesion Molecules; Axon-Associated Adhesion Molecules; Molecules, Axon-Associated Adhesion; Axon Associated Adhesion Molecules; Adhesion Molecules, Axon-Associated
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RGMB protein, human  0   *Cell Adhesion Molecules, Neuronal. Nat Genet 2006 May;38(5):531-9
synaptic adhesion-like molecule 4, rat  0   *Cell Adhesion Molecules, Neuronal. Mol Cell Neurosci. 2010 Nov;45(3):213-25
NB-2 protein, mouse  0   *Cell Adhesion Molecules, Neuronal. Dev Biol 2009 Dec 15;336(2):192-200
plexin D1, mouse  0   *Cell Adhesion Molecules, Neuronal. Nature 2009 Jun 11;459(7248):842-6
NRXN1 protein, human  0   *Nerve Tissue Proteins *Cell Adhesion Molecules, Neuronal. Hum Mol Genet 2009 Mar 1;18(5):988-96
PUNC protein, human  0   *Immunoglobulins *Cell Adhesion Molecules, Neuronal. J Pathol 2008 Feb;214(3):357-67
synCAM-2 protein, rat  0   *Cell Adhesion Molecules, Neuronal. BMC Neurosci 2007;8() (dup#62):90
contactin 6 protein, mouse  0   *Cell Adhesion Molecules, Neuronal. EMBO J 2008 Jan 9;27(1):188-200
Necl-4 protein, rat  0   *Cell Adhesion Molecules, Neuronal. Nat Neurosci 2007 Jul;10(7):861-9
NCAM140, human  0   *Cell Adhesion Molecules, Neuronal. Int J Cancer. 2007 Jun 15;120(12); 2625-34
gliomedin protein, mouse  0   *Cell Adhesion Molecules, Neuronal. J Biol Chem 2007 Apr 6;282(14):10647-59
nectin-like molecule 1, rat  0   *Cell Adhesion Molecules, Neuronal Immunoglobulins. Amino Acids 2006 Jun;30(4):409-15
CNTNAP5 protein, human  0   *Cell Adhesion Molecules, Neuronal. Mamm Genome 2006 Jul;17(7):723-31
NCAM140, rat  0   *Cell Adhesion Molecules, Neuronal. J Neurochem 2005 Dec;95(6):1777-84
Icam5 protein, mouse  0   *Membrane Glycoproteins *Nerve Tissue Proteins Immunoglobulins Cell Adhesion Molecules, Neuronal.
gliomedin, rat  0   *Cell Adhesion Molecules, Neuronal. Neuron 2005 Jul 21;47(2):215-29
Ninj2 protein, mouse  0   *Cell Adhesion Molecules, Neuronal.
NINJ2 protein, human  0   *Cell Adhesion Molecules, Neuronal.
Atp1b2 protein, rat  0   *Adenosine Triphosphatases *Cell Adhesion Molecules, Neuronal *Cation Transport Proteins.
Atp1b2 protein, mouse  0   *Adenosine Triphosphatases *Cell Adhesion Molecules, Neuronal *Cation Transport Proteins.
ATP1B2 protein, human  0   *Adenosine Triphosphatases *Cell Adhesion Molecules, Neuronal *Cation Transport Proteins.
PLXND1 protein, human  0   *Cell Adhesion Molecules, Neuronal. Pediatr Neurol 2004 Aug;31(2):114-8
CNTNAP1 protein, human  0   *Cell Adhesion Molecules, Neuronal.
Cntnap1 protein, mouse  0   *Cell Adhesion Molecules, Neuronal.
Nrx protein, Drosophila  0   *Cell Adhesion Molecules, Neuronal *Drosophila Proteins.
Stab2 protein, mouse  0   *Cell Adhesion Molecules, Neuronal.
Stab1 protein, mouse  0   *Cell Adhesion Molecules, Neuronal.
NEGR1 protein, human  0   *Cell Adhesion Molecules, Neuronal GPI-Linked Proteins.
Pcdha4 protein, rat  0   *Neuropeptides *Receptors, Cell Surface *Cell Adhesion Molecules, Neuronal.
PCDHA4 protein, human  0   *Neuropeptides *Receptors, Cell Surface *Cell Adhesion Molecules, Neuronal.
Ninj1 protein, mouse  0   *Nerve Growth Factors *Cell Adhesion Molecules, Neuronal.
NINJ1 protein, human  0   *Nerve Growth Factors *Cell Adhesion Molecules, Neuronal.
C3 synthetic NCAM-ligand  0   *Cell Adhesion Molecules, Neuronal. J Neurochem 2003 Feb;84(3):546-56
STAB2 protein, human  0   *Cell Adhesion Molecules, Neuronal. Biochem J 2002 Feb 15;362(Pt 1):155-64
STAB1 protein, human  0   *Cell Adhesion Molecules, Neuronal *Receptors, Lymphocyte Homing. Biochem J 2002 Feb 15;362(Pt 1):155-64
FAR-2 protein, chicken  0   *Cell Adhesion Molecules, Neuronal. Mol Cell Neurosci 2001 Jul;18(1):91-107
LAD-1 protein, C elegans  0   *Cell Adhesion Molecules, Neuronal *Caenorhabditis elegans Proteins. J Cell Biol 2001 Aug 20;154(4):841-55
Kilon protein, rat  0   *Cell Adhesion Molecules, Neuronal. J Biol Chem 1999 Mar 19;274(12):8224-30
LRRN2 protein, human  0   *Cell Adhesion Molecules, Neuronal. Oncogene 1998 Jun 11;16(23):2997-3002
MAGI1 protein, human  0   *Cell Adhesion Molecules, Neuronal. Biochem Biophys Res Commun 1998 Jun 29;247(3):597-604
Pcdha4 protein, mouse  0   *Neuropeptides *Receptors, Cell Surface *Cell Adhesion Molecules, Neuronal. Neuron 1998 Jun;20(6):1137-51
Punc protein, mouse  0   *Immunoglobulins *Cell Adhesion Molecules, Neuronal. Mech Dev 1998 Feb;71(1-2):201-4
SCO-spondin  0   *Cell Adhesion Molecules, Neuronal. J Cell Sci 1996 May;109( Pt 5):1053-61
CAM protein, Hirudo medicinalis  0   *Cell Adhesion Molecules, Neuronal. J Cell Biol 1997 Jul 14;138(1):143-57
tractin protein, Hirudo medicinalis  0   *Cell Adhesion Molecules, Neuronal. J Cell Biol 1997 Jul 14;138(1):143-57
ALCAM protein, human  0   *Fetal Proteins *Antigens, CD *Cell Adhesion Molecules, Neuronal Cell Adhesion. Blood 1997 Apr 15;89(8):2706-16
E587 protein, Carassius auratus  0   *Cell Adhesion Molecules, Neuronal *Fish Proteins. J Comp Neurol 1997 Jan 13;377(2):286-97
Caspr protein, rat  0   *Cell Adhesion Molecules, Neuronal. EMBO J 1997 Mar 3;16(5):978-88
Ninj1 protein, rat  0   *Nerve Growth Factors *Cell Adhesion Molecules, Neuronal. Neuron 1996 Aug;17(2):353-61
neuroligin 3  0   *Membrane Proteins *Nerve Tissue Proteins *Cell Adhesion Molecules, Neuronal. J Biol Chem 1996 Feb 2;271(5):2676-82
neuroligin 2  0   *Nerve Tissue Proteins *Cell Adhesion Molecules, Neuronal. J Biol Chem 1996 Feb 2;271(5):2676-82
limbic system-associated membrane protein  0   *Cell Adhesion Molecules, Neuronal GPI-Linked Proteins Immunoglobulin G. Neuron 1995 Aug;15(2):287-97
neuroligin 1  0   *Cell Adhesion Molecules, Neuronal. Cell 1995 May 5;81(3):435-43
reelin protein  EC 3.4.21.-   *Nerve Tissue Proteins *Serine Endopeptidases *Cell Adhesion Molecules, Neuronal *Extracellular Matrix Proteins Mice, Neurologic Mutants. Nature 1995 Apr 20;374(6524):719-23
ICAM5 protein, human  0   *Nerve Tissue Proteins *Cell Adhesion Molecules Immunoglobulins Cell Adhesion Molecules, Neuronal. Neuron 1994 Mar;12(3):541-53
roughest protein, Drosophila  0   *Eye Proteins *Cell Adhesion Molecules, Neuronal *Drosophila Proteins. Genes Dev 1993 Dec;7(12B):2533-47
Nrg protein, Drosophila  127496-12-2   *Cell Adhesion Molecules, Neuronal *Drosophila Proteins. Cell 1989;59(3):447
Fas3 (fasciclin 3) protein, Drosophila  0   *Cell Adhesion Molecules, Neuronal *Drosophila Proteins. Cell 1989;59(2):313
fasciclin II  0   *Cell Adhesion Molecules, Neuronal. Cell 1987;48(5):745
fasciclin I  0   *Cell Adhesion Molecules, Neuronal. Cell 1987;48(5):745
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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