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Cadherins

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Definition: Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.     
Examples Desmosomal Cadherins 		Other names Uvomorulin; P-Cadherins; Liver Cell Adhesion Molecules; N-Cadherins; E-Cadherins; P Cadherins; P Cadherin; N Cadherins; N Cadherin; Epithelial Cadherins; E Cadherins; E Cadherin; Cadherins, Placental; Cadherins, Neural; Cadherin 3; Cadherin 2; Cadherin 1; Placental Cadherins; P-Cadherin; Neural Cadherins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-cadherin protein, Drosophila  0   *Cadherins *Drosophila Proteins. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3); E127-34
N-cadherin, rat  0   *Nerve Tissue Proteins *Cadherins. J Cell Biol. 1988 Jul;107(1):353-61.
Celsr3 protein, zebrafish  0   *Cadherins *Zebrafish Proteins. PLoS Genet. 2011 Aug;7(8):e1002239.
cadherin-9, mouse  0   *Cadherins. Neuron. 2011 Aug 25;71(4):640-55
Celsr3 protein, human  0   *Receptors, Cell Surface *Cadherins. Adv Exp Med Biol. 2010;706():179-88
FMI-1 protein, C elegans  0   *Cadherins *Caenorhabditis elegans Proteins. Development. 2010 Nov;137(21):3663-73
Fat2 protein, Drosophila  0   *Cadherins *Drosophila Proteins. Development 2009 Dec;136(24):4123-32
protocadherin-9, zebrafish  0   *Cadherins *Zebrafish Proteins. Gene Expr Patterns 2009 Oct;9(7):490-6
protocadherin-19, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Biol 2009 Oct 1;334(1):72-83
protocadherin-17, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Genes Evol 2009 May;219(5):265-71
protocadherin 15, rat  0   *Cadherins. Exp Anim 2009 Jan;58(1):1-10
cadherin-7, zebrafish  0   *Cadherins *Zebrafish Proteins. Cell Tissue Res 2008 Oct;334(1):37-45
cadherin-10 protein, mouse  0   *Cadherins. Brain Res 2005 Oct 5;1058(1-2):62-72
FAT4 protein, human  0   *Cadherins *Tumor Suppressor Proteins. Int J Cancer 2009 Feb 15;124(4):793-8
Cad86C protein, Drosophila  0   *Cadherins *Drosophila Proteins. Mech Dev 2008 aug;125(8):712-28
cadherin 20 protein, rat  0   *Cadherins. BMC Dev Biol 2008;8() (dup#43):87
cadherin 7 protein, rat  0   *Cadherins. BMC Dev Biol 2008;8() (dup#43):87
protocadherin-18, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Biol 2008 Jun 15;318(2):335-46
protocadherin 17, human  0   *Cadherins. Proc Natl Acad Sci U S A 2007 Nov 6;104(45):17849-54
CDH-4 protein, C elegans  0   *Cadherins *Caenorhabditis elegans Proteins. Dev Biol 2008 Apr 15;316(2):249-59
Pcdh12 protein, rat  0   *Cadherins. J Cell Sci 2008 Jan 1;121(Pt 1):29-37
protocadherin beta16, mouse  0   *Neuropeptides *Cadherins. Eur J Neurosci. 2008 Feb;27(3):559-71
protocadherin 20 protein, mouse  0   *Nerve Tissue Proteins *Cadherins. J Comp Neurol 2008 Mar 1;507(1):1076-86
Celsr3 protein, rat  0   *Cadherins *Receptors, G-Protein-Coupled. Nat Neurosci 2007 Aug;10(8):963-9
Celsr2 protein, rat  0   *Cadherins *Receptors, G-Protein-Coupled. Nat Neurosci 2007 Aug;10(8):963-9
Fat3 protein, mouse  0   *Cadherins. Dev Dyn 2007 Feb;236(2):534-43
cadherin10 protein, zebrafish  0   *Cadherins *Zebrafish Proteins Nerve Tissue Proteins. Gene Expr Patterns 2006 Oct;6(7):703-10
N-cadherin, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Dyn 1994 Oct;201(2):121-36
CDH1 protein, human  0   *Cadherins.
PCNS protein, Xenopus  0   *Cadherins *Xenopus Proteins. Dev Biol 2006 Jul 1;295(1):206-18
CDH3 protein, human  0   *Cadherins. J Med Genet 2005 Apr;42(4):292-8
Cad99c protein, Drosophila  0   *Cadherins. Dev Biol 2005 Mar 1;279(1):142-54
Pcdha10 protein, mouse  0   *Cadherins. Genes Cells 2006 Jan;11(1):95-7
protocadherin 10 protein, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Dyn 2006 Feb;235(2):506-14
Fat4 protein, mouse  0   *Cadherins. J Mol Biol 2004 Mar 19;337(2):307-17
Dchs1 protein, mouse  0   *Cadherins. Dev Dyn 2005 Nov;234(3):747-55
Mucdhl protein, rat  0   *Cadherins.
Mucdhl protein, mouse  0   *Cadherins.
Pcdh12 protein, mouse  0   *Cadherins.
Cdh8 protein, mouse  0   *Cadherins.
Cdh8 protein, rat  0   *Cadherins.
Cdh22 protein, mouse  0   *Cadherins.
Cdh22 protein, rat  0   *Cadherins.
Pcdh1 protein, mouse  0   *Cadherins.
Pcdhgc3 protein, mouse  0   *Cadherins.
celsr1b protein, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Biol. 2005 Jun 15;282(2):320-35
celsr1a protein, zebrafish  0   *Cadherins *Zebrafish Proteins. Dev Biol. 2005 Jun 15;282(2):320-35
Fath protein, mouse  0   *Cadherins.
Fath protein, rat  0   *Cadherins.
FAT2 protein, human  0   *Cadherins.
FAT1 protein, human  0   *Cadherins Genes, Tumor Suppressor.
shotgun protein, Drosophila  0   *Cadherins *Drosophila Proteins. Dev Cell 2005 Apr;8(4):493-504
cadherin 19, rat  0   *Cadherins. Dev Dyn 2005 Jan;232(1):200-8
Cdh7 protein, mouse  0   *Cadherins.
Cdh20 protein, mouse  0   *Cadherins.
cdh23 protein, zebrafish  0   *Cadherins *Zebrafish Proteins.
Cdh23 protein, mouse  0   *Cadherins.
PCDH15 protein, human  0   *Cadherins.
fmi1 protein, Xenopus  0   *Cadherins *Xenopus Proteins.
Celsr2 protein, mouse  0   *Cadherins.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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