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Cysteine Proteinase Inhibitors

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Definition: Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.  /biosyn /physiol permitted only with endogenous proteinase inhib; DF: CYSTEINE PROTEINASE INHIB    Other names Cysteine Proteinase Inhibitors, Exogenous; Cysteine Proteinase Inhibitors, Endogenous; Cysteine Proteinase Antagonists; Cysteine Protease Inhibitors; alpha Cysteine Protease Inhibitors; Proteinase Inhibitors, Cysteine; Proteinase Antagonists, Cysteine; Protease Inhibitors, alpha-Cysteine; Protease Inhibitors, Cysteine; Inhibitors, alpha-Cysteine Protease; Inhibitors, Cysteine Proteinase; Inhibitors, Cysteine Protease; Antagonists, Cysteine Proteinase; alpha-Cysteine Protease Inhibitors; Acid Cysteine Proteinase Inhibitors
Substances having this pharmacologic action: benzyloxycarbonylphenylalanylalanine diazomethyl ketone; E 64; 4-hydroxy-2-nonenal; leupeptin; calpastatin; calpain inhibitors; phenylalanyl-prolyl-arginine-chloromethyl ketone; geldanamycin; Cystatin B; Salivary Cystatins; benzyloxycarbonyl-isoleucyl-glutamyl(O-tert-butyl)-alanyl-leucinal; Kininogens; Cystatins; BIRC5 protein, human; aloxistatin; aspartyl-glutamyl-valyl-aspartal; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone; Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone; L 709049; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone; N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone; clasto-lactacystin beta-lactone; acetyl-aspartyl-glutamyl-valyl-aspartal; cystatin, egg-white; nitroaspirin; butyloxycarbonyl-O-methyl-aspartyl-fluoromethyl ketone; inhibitor of apoptosis, Nucleopolyhedrovirus; lactacystin; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline; N-acetylleucyl-leucyl-methioninal; calpeptin; benzyloxycarbonylleucyl-leucyl-leucine aldehyde; acetylleucyl-leucyl-norleucinal; MDL 201053; calpain inhibitor III
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
interleukin-1beta-converting enzyme inhibitor  96282-35-8   *Viral Proteins *Serpins Cysteine Proteinase Inhibitors. Cell 1992 May 15;69(4):597-604
ovocystatin  0   Peptides Cysteine Proteinase Inhibitors. Microbiol Immunol 1991;35(7):583-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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