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Complement C4a

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Definition: The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A.     
Pharmacological Action Immunologic Factors 		Other names Component 4a, Complement; Complement, C4a; C4a, Complement; Complement Component 4a; Complement 4a; C4a Complement
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
complement C4a, des-Arg  0   *Complement C4a. Arthritis Rheum 1986;29(12):1467

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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