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Complement C4b

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Definition: The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).     
Pharmacological Action Immunologic Factors 		Other names Component 4b, Complement; Complement, C4b; C4b, Complement; Complement Component 4b; Complement 4b; C4b Complement
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
complement C4c  0   *Peptide Fragments *Complement C4b. Biochem J 1981;199(2):351
complement C4d  80295-52-9   *Peptide Fragments *Complement C4b. Am J Clin Pathol 1981;76(5):679

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