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Retinoblastoma Protein

More information in Books or onNLM PubMed
Definition: Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.  /biosyn /drug eff /physiol /ultrastruct permitted    Other names p105-Rb Protein; Retinoblastoma Nuclear Phosphoprotein p105-Rb; Rb Protein; p105 Rb Protein; Retinoblastoma Nuclear Phosphoprotein p105 Rb; Rb1 Gene Product; Rb Gene Product
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
LIN9 protein, human  0   *Nuclear Proteins *Tumor Suppressor Proteins Retinoblastoma Protein. EMBO J 2004 Nov 24;23(23):4627-38
mat3 protein, Chlamydomonas  0   *Protozoan Proteins *Retinoblastoma Protein. Genes Dev 2001 Jul 1;15(13):1652-61
EID1 protein, human  0   *Nuclear Proteins *Repressor Proteins Retinoblastoma Protein. Cytogenet Cell Genet 2000;88(3-4):330-2; Mol Cell Biol 2000 Dec;20(23):8889-902
lin-36 protein, C elegans  0   *Retinoblastoma Protein *Caenorhabditis elegans Proteins. Development 1999 Aug;126(15):3449-59
RRB2 protein, Zea mays  0   *Plant Proteins *Cell Cycle Proteins Retinoblastoma Protein. Mol Cell Biol 1997 Sep;17(9):5077-86
RRB1 protein, Zea mays  0   *Plant Proteins *Cell Cycle Proteins Retinoblastoma Protein. Mol Cell Biol 1997 Sep;17(9):5077-86
Rbf protein, Drosophila  0   *Transcription Factors *Retinoblastoma Protein *Drosophila Proteins. Genes Dev 1996 May 15;10(10):1206-18
retinoblastoma protein p95  0   *Retinoblastoma Protein. Proc Natl Acad Sci USA 1990;87(1):6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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