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Free Radical Scavengers

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Definition: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.     
See Also Free Radicals 		Other names Scavengers, Free Radical
Substances having this pharmacologic action: bisphenol A; abietic acid; 4-coumaric acid; 1,3-dimethylthiourea; anisodamine; indol-3-yl pyruvic acid; ferulic acid; bathocuproine; phenylmethylpyrazolone; allicin; Superoxide Dismutase; Nitric Oxide; 3-Hydroxyanthranilic Acid; Pentoxifylline; Dimethyl Sulfoxide; Acetylcysteine; Allopurinol; terephthalic acid; manganese(III)-tetrakis(4-benzoic acid)porphyrin; 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; 3,4,5-trihydroxybenzamidoxime; lithospermate B; 1-(carboxymethylthio)tetradecane; polyethylene glycol-superoxide dismutase; glutathione monoisopropyl ester; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
puerarin-7-O-fructoside  0   *Isoflavones Fructose/*analogs & derivatives Free Radical Scavengers. Folia Microbiol (Praha). 2011 Jul;56(4):305-11
(E)-6-(2,4-dihydroxyl-5-methylphenyl)-6-oxo-2-hexenoic acid  0   *Resorcinols Free Radical Scavengers. J Antibiot (Tokyo). 2011 Sep;64(9):645-7
6-(2,4-dihydroxyl-5-methylphenyl)-6-oxohexanoic acid  0   *Resorcinols Free Radical Scavengers. J Antibiot (Tokyo). 2011 Sep;64(9):645-7
3,11,12,14,19-pentahydroxy-5,8,11,13-abietatraen-7-pyran(4,6)-16-dione  0   *Diterpenes Free Radical Scavengers. Nat Prod Commun. 2011 Sep;6(9):1229-32
CPI-1429  0   *Benzene Derivatives Free Radical Scavengers. Mech Ageing Dev 2002 Apr 30;123(8):1021-31
O-J-R9188  0   Deoxyguanosine/*analogs & derivatives Free Radical Scavengers. J Surg Res 2001 Nov;101(1):91-8
6-acyl-ascorbic acid-2-glucoside  0   Ascorbic Acid/*analogs & derivatives Free Radical Scavengers. Chem Pharm Bull (Tokyo) 2001 May;49(5):642-4
6-chloroepicatechin  0   Catechin/*analogs & derivatives Free Radical Scavengers. Phytochemistry 2001 Jan;56(2):189-93
myricetin 3-O-(2''-O-galloyl)-beta-D-glucopyranoside  0   *Glycosides Free Radical Scavengers. Phytochemistry 2001 Jan;56(2):189-93
J811 scavestrogen  0   *Estradiol Free Radical Scavengers. Toxicol Appl Pharmacol 1998 Sep;152(1):49-55
J861 scavestrogen  0   *Estradiol Free Radical Scavengers. Toxicol Appl Pharmacol 1998 Sep;152(1):49-55
Griess reagent  0   *Ethylenediamines *Sulfanilamides Free Radical Scavengers. FEBS Lett 1995 Jul 24;368(3):425-8
phenyl-N-tert-butylnitrone  3376-24-7   *Cyclic N-Oxides Spin Labels Free Radical Scavengers.
Pharma Action Neuroprotective Agents 		Arch Biochem Biophys 180:480;1977; Biochim Biophys Acta 539(3):402;1978; FEBS Lett 1980;122(2):303

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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