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Granulocyte Colony-Stimulating Factor

More information in Books or onNLM PubMed
Definition: A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.  DF: GCSF   
See Also Receptors, Granulocyte Colony-Stimulating Factor 		Other names G-CSF
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Filgrastim  121181-53-1   *Granulocyte Colony-Stimulating Factor Recombinant Proteins.
Maxy G34  0   *Polyethylene Glycols *Granulocyte Colony-Stimulating Factor Recombinant Proteins. Cell Prolif 2009 Dec;42(6):823-37
hematopoietic lineage cell-specific protein 1, mouse  0   *Granulocyte Colony-Stimulating Factor. Blood 2007 Oct 1;110(7):2449-56
Tia1 protein, mouse  0   *RNA-Binding Proteins RNA Splicing Granulocyte Colony-Stimulating Factor.
pegylated granulocyte colony-stimulating factor, human  0   *Polyethylene Glycols *Granulocyte Colony-Stimulating Factor. Blood 2004 May 1;103(9):3573-81
pegfilgrastim  0   *Granulocyte Colony-Stimulating Factor Recombinant Proteins Neutropenia/drug therapy. Med Lett Drugs Ther 2002 May 13;44(1130):44-5NEULASTA
OLFM4 protein, human  0   *Granulocyte Colony-Stimulating Factor. Gene 2002 Jan 23;283(1-2):83-93
EVAC-G-CSF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Vinblastine Granulocyte Colony-Stimulating Factor. Am J Clin Oncol 2001 Dec;24(6):551-5
pegylated granulocyte colony-stimulating factor  0   *Polyethylene Glycols *Granulocyte Colony-Stimulating Factor Recombinant Proteins. Am J Hematol 2001 Apr;66(4):245-51
CLAG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Granulocyte Colony-Stimulating Factor Cladribine. Leuk Lymphoma. 2000 Sep;39(1-2):121-9
SD-01 recombinant  0   *Granulocyte Colony-Stimulating Factor Recombinant Proteins. Br J Haematol 2000 Sep;110(3):638-46
CAG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Aclarubicin Granulocyte Colony-Stimulating Factor. Int J Hematol 2000 Apr;71(3):238-44
myelopoietin  0   *Interleukin-3 *Recombinant Fusion Proteins *Granulocyte Colony-Stimulating Factor. Biochemistry 1999 Apr 6;38(14):4564-71
leridistim  193700-51-5   *Interleukin-3 *Recombinant Fusion Proteins *Granulocyte Colony-Stimulating Factor. Clin Pharmacol Ther 1999 Nov;66(5):545
Ida-FLAG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Vidarabine/*analogs & derivatives Idarubicin Granulocyte Colony-Stimulating Factor. Ann Hematol 1999 Sep;78(9):418-25
THP-COPBLM regimen  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin/analogs & derivatives Prednisone Procarbazine Vincristine Granulocyte Colony-Stimulating Factor. Leukemia 1997 Nov;11(11):1817-20
SCH 14988  0   *Naphthyridines Granulocyte Colony-Stimulating Factor. Blood 1997 Jul 15;90(2):795-802
MAD protocol  0   Cytarabine *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Mitoxantrone Granulocyte Colony-Stimulating Factor. J Clin Oncol 1997 Feb;15(2):491-8
FLANG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Mitoxantrone Vidarabine/analogs & derivatives Granulocyte Colony-Stimulating Factor. Leuk Lymphoma 1996 Jun;22(1-2):173-6
FLAG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Vidarabine/analogs & derivatives Granulocyte Colony-Stimulating Factor. Br J Haematol 1994 Feb;86(2):394-6
lenograstim  135968-09-1   *Granulocyte Colony-Stimulating Factor Recombinant Proteins.
Pharma Action Adjuvants, Immunologic 		Clin Pharmacol Ther 1992 Jul;52(1):113
nartograstim  134088-74-7 Colony-stimulating factor (human clone 1034), 1-(N-L-methionyl-L-alanine)-3-L-threonine-4-L-tyrosine-5-L-arginine-17-L-serine  *Granulocyte Colony-Stimulating Factor.
Pharma Action Antineoplastic Agents 		J Urol 1992;147(1):283
granulocyte colony-stimulating factor, Tyr(1)-Tyr(3)  0   *Granulocyte Colony-Stimulating Factor Recombinant Proteins. Anal Biochem 1991;195(1):38

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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