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Receptor, Macrophage Colony-Stimulating Factor

More information in Books or onNLM PubMed
Definition: A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.  DF: RECEPT MCSF   
See Also Genes, fms 		Other names fms Proto-Oncogene Protein; c-fms Protein; Receptor, CSF-1; Proto-Oncogene Protein fms; CSF-1 Receptor; CD115 Antigens; Antigens, CD115; fms Proto Oncogene Protein; c fms Protein; Receptors, Macrophage Colony Stimulating Factor; Receptors, M CSF; Receptors, CSF 1; Receptor, Macrophage Colony Stimulating Factor; Receptor, CSF 1; Proto-Oncogene Protein, fms; Macrophage Colony Stimulating Factor Receptors; CSF-1 Receptors; Antigen, CD115; Receptors, Macrophage Colony-Stimulating Factor; Receptors, M-CSF
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-(2-(2-hydroxycyclohexylamino)benzothiazol-6-yloxy)pyridine-2-carboxylic acid methylamide  0   *Picolinic Acids *Benzothiazoles Receptor, Macrophage Colony-Stimulating Factor/antagonists & inhibitors. Int J Toxicol 2011 May;30(3):300-12
BARF1 protein, Human herpesvirus 4  0   *Viral Proteins Receptor, Macrophage Colony-Stimulating Factor. Cancer Res 1994 Apr 1;54(7):1843-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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