Definition: Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
Other names p34cdc2 Protein; Protein p34cdc2; Histone Kinase p34(cdc2); Cyclin-Dependent Kinase 1; Cdk1 Protein Kinase; p34cdc2, Protein; Protein Kinase, Cdk1; Protein Kinase, CDC2; Cyclin Dependent Kinase 1; cdk1 Kinase; cdc2+ Protein