Definition: Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
/drug eff /ultrastruct permitted; DF: note short X refs
Other names p62(c-myc); myc Proto-Oncogene Proteins; c-myc Proteins; N-myc Proteins; L-myc Proteins; p62 c myc; myc, Proto-Oncogene Proteins; myc Proto Oncogene Proteins; myc Proto Oncogene Product p62; c myc Proteins; Proto-Oncogene Proteins, myc; Proto Oncogene Proteins myc; Proto Oncogene Proteins c myc; Proto Oncogene Products c myc; Proteins myc, Proto-Oncogene; N myc Proteins; L myc Proteins; p62 c-myc; myc Proto-Oncogene Product p62; Proto-Oncogene Proteins myc