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Proto-Oncogene Proteins c-myc

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Definition: Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.  /drug eff /ultrastruct permitted; DF: note short X refs    Other names p62(c-myc); myc Proto-Oncogene Proteins; c-myc Proteins; N-myc Proteins; L-myc Proteins; p62 c myc; myc, Proto-Oncogene Proteins; myc Proto Oncogene Proteins; myc Proto Oncogene Product p62; c myc Proteins; Proto-Oncogene Proteins, myc; Proto Oncogene Proteins myc; Proto Oncogene Proteins c myc; Proto Oncogene Products c myc; Proteins myc, Proto-Oncogene; N myc Proteins; L myc Proteins; p62 c-myc; myc Proto-Oncogene Product p62; Proto-Oncogene Proteins myc
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
omomyc protein  0   *Peptide Fragments *Proto-Oncogene Proteins c-myc Proto-Oncogene Proteins c-myc/antagonists & inhibitors. Oncogene. 1998 Nov 12;17(19):2463-72.
5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one  0   *Thiazoles Proto-Oncogene Proteins c-myc/antagonists & inhibitors. J Pediatr Surg 2006 Jan;41(1):207-11
XR1 protein, Xenopus  0   *Proto-Oncogene Proteins c-myc *Xenopus Proteins.
Myc protein, mouse  0   *Proto-Oncogene Proteins c-myc.
MYC protein, human  0   *Proto-Oncogene Proteins c-myc.
Bmyc protein, mouse  0   *Proto-Oncogene Proteins c-myc Epididymis. Biol Reprod 2001 Jun;64(6):1600-7
IMP-1 protein, human  0   *RNA-Binding Proteins Proto-Oncogene Proteins c-myc. Mol Cell Biol 1997 Apr;17(4):2158-65; Mol Pharmacol 2000 Mar;57(3):485-94
MYC7E protein, Zea mays  0   *Plant Proteins *Transcription Factors *Proto-Oncogene Proteins c-myc. Gene 1998 Dec 28;225(1-2):47-57
transformation-transcription domain-associated protein  0   *Nuclear Proteins *Adaptor Proteins, Signal Transducing Proto-Oncogene Proteins c-myc. Cell 1998 Aug 7;94(3):363-74
ZBTB17 protein, human  0   *Kruppel-Like Transcription Factors Proto-Oncogene Proteins c-myc Zinc Fingers. Mech Dev 1997 Jul;65(1-2):3-17
cysteine-rich protein, avian  0   *Muscle Proteins *Proto-Oncogene Proteins c-myc *Avian Proteins Carrier Proteins Cell Adhesion Zinc Fingers. Proc Natl Acad Sci U S A 1993 May 15;90(10):4404-8
Bmyc protein, rat  0   *Proto-Oncogene Proteins c-myc. J Clin Lab Immunol 1990 Jun;32(2):49-54
c-MYC-associated zinc finger protein  0   *DNA-Binding Proteins *Transcription Factors Proto-Oncogene Proteins c-myc Zinc Fingers. Proc Natl Acad Sci U S A 1992 Aug 15;89(16):7452-6
c-Myc1 protein, Xenopus  139106-80-2   *Proto-Oncogene Proteins c-myc *Xenopus Proteins. Nucleic Acids Res 1991;19(11):3081
c-myc II protein, Xenopus  139107-27-0   *Proto-Oncogene Proteins c-myc *Xenopus Proteins. Nucleic Acids Res 1991;19(11):3081

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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