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RNA, Catalytic

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Definition: RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.     
Examples Ribonuclease P; RNA, Ribosomal, Self-Splicing 		Other names Ribozymes; Catalytic RNA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Diels-Alder ribozyme  0   *RNA, Catalytic. Chem Biol 1999 Mar;6(3):167-76
2PTmin3.2 ribozyme  0   *RNA, Catalytic *Phosphotransferases (Alcohol Group Acceptor). Biochemistry 2005 Nov 15;44(45):15007-16
R3C ligase  EC 6.5.1.-   *Polynucleotide Ligases *RNA, Catalytic. Proc Natl Acad Sci U S A 2002 Oct 1;99(20):12733-40
varkud satellite ribozyme  EC 3.1.27.-   *Endoribonucleases *RNA, Catalytic. EMBO J 2001 Oct 1;20(19):5461-9
ribozyme UV5  0   *RNA, Catalytic. Chem Biol. 2001 May;8(5):459-73
hammerhead ribozyme RZ-NBC  0   *RNA, Catalytic. J Clin Invest 2001 Jul;108(1):107-115
hammerhead ribozyme  0   *RNA, Catalytic. Biopolymers 1999;52(3):147-54
hammerhead ribozyme RZ3-BL2  0   *RNA, Catalytic. Nucleosides Nucleotides Nucleic Acids 2000 Aug;19(8):1273-9
VA1-ribozyme chimera  0   *RNA, Catalytic. Antisense Nucleic Acid Drug Dev. 2000 Aug;10(4):251-61
sunY ribozyme  0   *RNA, Catalytic. Biotechniques 2000 Aug;29(2):344-51
hairpin ribozyme  0   *RNA, Catalytic. RNA 2000 Dec;6(12):1833-46
alpha VRz  0   *RNA, Catalytic. Int J Oncol 2000 Sep;17(3):495-9
7-deaza-R34  0   *RNA, Catalytic. Nucleic Acids Symp Ser 1999;(42):283-4
DiGIR1 ribozyme  0   *RNA, Catalytic. Nucleic Acids Res 2000 May 15;28(10):2194-200
Rz967  0   *RNA, Catalytic. Cancer Gene Ther 1999 May-Jun;6(3):263-70
Angiozyme  0   *RNA, Catalytic. Antisense Nucleic Acid Drug Dev 1999 Jun;9(3):271-7
GIR1 ribozyme  0   *RNA, Catalytic. RNA 1998 Dec;4(12):1481-92
leadzyme  0   *RNA, Catalytic Lead RNA, Transfer. RNA 1998 Jul;4(7):739-49
Copia protein, Drosophila  EC 3.4.23.-   *Peptide Hydrolases *Retroelements *Drosophila Proteins RNA, Catalytic. EMBO J 1990;9(2):535

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