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Lymphoma, Large B-Cell, Diffuse

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Definition: Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.  DF: LYMPHOMA LARGE DIFFUSE    Other names Lymphoma, Histiocytic, Diffuse; Histiocytic Lymphoma, Diffuse; Diffuse, Large B-Cell, Lymphoma; Lymphomas, Large-Cell; Lymphomas, Histiocytic; Lymphomas, Diffuse Large-Cell; Lymphomas, Diffuse Histiocytic; Lymphoma, Large Cell; Lymphoma, Diffuse Large Cell; Lymphoma, Diffuse Histiocytic; Large-Cell Lymphomas, Diffuse; Large-Cell Lymphomas; Large Cell Lymphoma, Diffuse; Large Cell Lymphoma; Histiocytic Lymphomas, Diffuse; Histiocytic Lymphomas; Diffuse Large-Cell Lymphomas; Diffuse Large Cell Lymphoma; Diffuse Histiocytic Lymphomas; Diffuse Histiocytic Lymphoma
 
SubstanceCAS Registry & nameCategoriesSource
R-CHOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Doxorubicin Prednisone Vincristine Antibodies, Monoclonal, Murine-Derived Lymphoma, Large B-Cell, Diffuse/drug therapy. Br J Haematol. 2012 Jan;156(1):142-3

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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