Definition: Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
radiother by cytotoxic radioisotopes linked to antibodies: read MeSH definition; do not use /util except by MeSH definition; coord IM with disease /radiother (IM)
Other names Radioimmunotherapies; Immunoradiotherapies; Immunoradiotherapy