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Purpura, Thrombocytopenic, Idiopathic

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Definition: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.      Other names Werlhof's Disease; Purpura, Thrombocytopenic, Autoimmune; Idiopathic Thrombocytopenic Purpura; Autoimmune Thrombocytopenic Purpura; Werlhofs Disease; Thrombocytopenic Purpuras, Idiopathic; Thrombocytopenic Purpuras, Autoimmune; Thrombocytopenic Purpura, Idiopathic; Thrombocytopenic Purpura, Autoimmune; Thrombocytopenias, Autoimmune; Thrombocytopenia, Autoimmune; Purpuras, Idiopathic Thrombocytopenic; Purpuras, Autoimmune Thrombocytopenic; Purpura, Idiopathic Thrombocytopenic; Purpura, Autoimmune Thrombocytopenic; Idiopathic Thrombocytopenic Purpuras; Disease, Werlhof's; Disease, Werlhof; Autoimmune Thrombocytopenic Purpuras; Autoimmune Thrombocytopenias

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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