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Mitomycin

More information in Books or onNLM PubMed
Definition: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.  MITOMYCINS is also available   
Pharmacological Action Alkylating Agents; Antibiotics, Antineoplastic; Cross-Linking Reagents; Nucleic Acid Synthesis Inhibitors 		Other names Mitomycin C; NSC26980; NSC 26980; MitocinC; Mitocin C; NSC-26980; Mutamycin; Mitomycin-C; Mitocin-C; AmetycineDrugs* : MUTAMYCIN; MITOSOL; MITOMYCIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
desmethoxymitomycin A  0   Mitomycin. J Org Chem. 2004 Oct 15;69(21):7309-16
Mitozytrex  0   *Mitomycin. Expert Rev Anticancer Ther 2002 Dec;2(6):618-9MITOZYTREX
DMAP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dacarbazine Doxorubicin Mitomycin. Cancer Invest 2002;20(5-6):605-12
IMAP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Ifosfamide Mitomycin. Cancer 2002 Feb 1;94(3):786-92
BEMP protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Vindesine Mitomycin. Ann Oncol 2001 Jul;12(7):967-74
FILM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Leucovorin Fluorouracil Ifosfamide Mitomycin. Cancer Chemother Pharmacol 1999 ;44 Suppl:S18-23
MPEMi protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Leucovorin Etoposide Methotrexate Mitomycin. Breast Cancer Res Treat 1999 Jul;56(2):125-32
FLMP protocol  0   Leucovorin *Antineoplastic Combined Chemotherapy Protocols Cisplatin Fluorouracil Mitomycin. Gan To Kagaku Ryoho 1999 Nov;26(13):2043-8
PMUE protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Fluorouracil Mitomycin. Gan To Kagaku Ryoho 1999 Apr;26(5):691-5
MEP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Epirubicin Mitomycin. Oncology 1998 Mar-Apr;55(2):116-21
THP-FLPM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Leucovorin Doxorubicin/analogs & derivatives Fluorouracil Mitomycin. Gan To Kagaku Ryoho 1998 Jan;25(1):139-42
FTM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin/analogs & derivatives Fluorouracil Mitomycin. Gan To Kagaku Ryoho 1997 Dec;24(15):2233-8
MECCA protocol  0   Cisplatin *Antineoplastic Combined Chemotherapy Protocols Etoposide Carboplatin Mitomycin. Gynecol Oncol 1996 Dec;63(3):345-51
MVC regimen  0   *Antineoplastic Combined Chemotherapy Protocols Vinblastine Carboplatin Mitomycin. Cancer 1996 Oct 15;78(8):1701-7
FEMP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Fluorouracil Prednisolone Mitomycin. Anticancer Res 1995 Nov-Dec;15(6B):2907-12
PEM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Mitomycin. Gan To Kagaku Ryoho 1995 Aug;22 Suppl 3:209-14
FMP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Fluorouracil Mitomycin. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1994 Nov;14(11):661-3
MALF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Leucovorin Doxorubicin Fluorouracil Mitomycin. Br J Cancer 1995 Mar;71(3):605-9
POMP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Vincristine Mitomycin Peplomycin. Gan To Kagaku Ryoho 1995 Jan;22(1):53-8
HMiVe protocol  0   *Antineoplastic Combined Chemotherapy Protocols Altretamine Vinblastine Mitomycin. Am J Clin Oncol 1994 Dec;17(6):527-37
MICE regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Ifosfamide Vindesine Mitomycin. Eur J Cancer 1993;29A:1848-50
mitomycin C-N(2)-deoxyguanosine adduct  0   *Deoxyguanosine *Mitomycin. Biochemistry 1993 May 11;32(18):4708-18
F-FOMi protocol  0   *Antineoplastic Combined Chemotherapy Protocols Leucovorin Fluorouracil Vincristine Mitomycin. Am J Clin Oncol 1992;15(6):506-8
MVPF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Procarbazine Vinblastine Mitomycin. Am J Clin Oncol 1992 Dec;15(6):480-6
MV protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Vindesine Mitomycin. Cancer Chemother Pharmacol 1992;30(3):212-4
MIP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Ifosfamide Mitomycin. Am J Clin Oncol 1992 Feb;15(1):23-8
MVMF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Tegafur Methotrexate Vincristine Mitomycin. Jpn J Clin Oncol 1991;21(5):334
MTV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Thiotepa Vindesine Mitomycin. Ann Oncol 1991;2(5):347
FIM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Ifosfamide Mitomycin. Ann Oncol 1991;2(2):153
MMC complex  0   *Succinates *Mitomycin Agmatine/*analogs & derivatives. J Enzym Inhib 1990;4(1):63
MBCF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carmustine Cisplatin Fluorouracil Mitomycin. Korean J Intern Med 1987;2(1):48
CAP-M protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cyclophosphamide Doxorubicin Mitomycin. J Surg Oncol 1991;46(1):15
PMUE protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Tegafur Mitomycin. Gan To Kagaku Ryoho 1990;17(12):2381
Mallinson protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Fluorouracil Methotrexate Vincristine Mitomycin. Cancer 1990;65(10):2207
BOM regimen  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Vincristine Mitomycin. Gynecol Oncol 1990;37(1):21
MAC-VD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Etoposide Mitomycin Floxuridine. Gan To Kagaku Ryoho 1990;17(3 Pt 1):397
HexMF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Altretamine Mitomycin. Oncology 1989;46(6):366
FEM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Epirubicin Mitomycin. Nippon Gan Chiryo Gakkai Shi 1989;24(8):1551
PPM protocol  0   Mitomycin *Antineoplastic Combined Chemotherapy Protocols Cisplatin Peplomycin. Hinyokika Kiyo 1988;34(8):1377
MQF-OK-FT protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carbazilquinone Fluorouracil Tegafur Picibanil Mitomycin. Gan To Kagaku Ryoho 1988;15(7):2065
mitomycin C-DNA adduct  0   *Mitomycin *DNA Adducts. Biochemistry 1988;27(9):3182
PMU protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Cisplatin Tegafur Mitomycin. Gan To Kagaku Ryoho 1988;15(4 Pt 1):655
MCM protocol  0   Lomustine *Antineoplastic Combined Chemotherapy Protocols Methotrexate Mitomycin. J Clin Oncol 1988;6(1):5
MC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Mitomycin. J Clin Oncol 1987;(11):1791
PMFV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Fluorouracil Vincristine Mitomycin. Chung Hua Chung Liu Tsa Chih 1987;9(2):136
MMM protocol 2  0   Mitomycin *Antineoplastic Combined Chemotherapy Protocols Methotrexate Mitoxantrone. Lancet 1987;1(8538):915
AVM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Vinblastine Mitomycin. Cancer Chemother Pharmacol 1986;18(2):162
MAP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Mitomycin. Am J Cln Oncol 1986;9(3):249
MiPE protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Vindesine Mitomycin. Cancer Treat Rep 1986;70(9):1091
MMF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Semustine Mitomycin. J Clin Oncol 1986;4(4):565
mitomycin C-immunoglobulin M antibody conjugate  0   *Antibodies, Monoclonal *Mitomycin Immunotoxins Immunoglobulin G. J Appl Biochem 1984;6(5-6):297
FML protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Lentinan Mitomycin. Cancer 1985;55(10):2498
BOMP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Vincristine Mitomycin. Gynecol Oncol 1985;20(3):387
VMM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Methotrexate Teniposide Mitomycin. Bull Cancer (Paris) 1984;71(5):432
MEPH protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Altretamine Mitomycin. Am J Clin Oncol 1984;7(5):419
mitomycin C-dextran  0   *Dextrans *Mitomycin. Drug Metab Dispos 1984;12(4):492
mitomycin C-anti-alpha-fetoprotein antibody conjugate  0   *Antibodies *Mitomycin alpha-Fetoproteins Immunotoxins. J Appl Biochem 1983;5(4-5):313
DMV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitolactol Vinblastine Mitomycin. Eur J Cancer Clin Oncol 1984;20(7):873
MMM protocol 1  0   *Antineoplastic Combined Chemotherapy Protocols Melphalan Methotrexate Mitomycin. Cancer Chemother Pharmacol 1984;13(1):36
UFTM protocol  0   Uracil Tegafur *Antineoplastic Combined Chemotherapy Protocols Mitomycin. Gan To Kagaku Ryoho 1984;11(3 pt 2):769
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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