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Antigens, Human Platelet

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Definition: Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy.  restrict to antigens expressed on only platelets: do not confuse with HLA & other antigens expressed on platelets or other blood cells    Other names Platelet-Specific Antigens; Platelet Alloantigens; Human Platelet Antigens; Antigens, Platelet-Specific; Platelet Specific Antigens; Platelet Antigens, Human; Antigens, Platelet Specific; Alloantigens, Platelet
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
HPA-17w  0   *Antigens, Human Platelet. Transfus Med 2009 Feb ;19(1):55-6
HPA-8bw antigen, human  0   *Antigens, Human Platelet. J Thromb Haemost 2008 Feb;6(2):376-83
4b alloantigen, human  0   *Antigens, Human Platelet. Int J Immunogenet 2005 Jun;32(3):165-6
9bw alloantigen, human  0   *Antigens, Human Platelet. Transfusion 2005 Nov;45(11):1799-803
2a alloantigen, human  0   *Antigens, Human Platelet. Blood 1998 Oct 15;92(8):2771-6
12bw alloantigen, human  0   *Antigens, Human Platelet. Beitr Infusionsther Transfusionsmed 1994;32:247-9
6b alloantigen, human  0   *Antigens, Human Platelet Platelet Membrane Glycoproteins Thrombocytopenia. Tissue Antigens 1997 Aug;50(2):113-8
human platelet antigen 1b  0   *Antigens, Human Platelet Epitopes. Hum Immunol 1992 Aug;34(4):253-6
3b alloantigen, human  0   *Antigens, Human Platelet Epitopes. Blood 1991 Aug;78(3):681-7
2b alloantigen, human  0   *Antigens, Human Platelet Epitopes. Blood 1991;78(7):1722
5a alloantigen, human  0   *Antigens, Human Platelet Epitopes. Vox Sang 1991;60(4):230
Naka isoantigen, human  0   *Antigens, Human Platelet Epitopes. Vox Sang 1989;57(3):213
4a alloantigen, human  0   *Antigens, Human Platelet Epitopes. Am J Hematol 1988;29(1):38
5b alloantigen, human  0   *Antigens, Human Platelet Epitopes. Vox Sang 1988;54(2):101
3a alloantigen, human  0   *Antigens, Human Platelet Epitopes. Obstet Gynecol 1985;65(3 Supp 1):20S
1a alloantigen, human  0   *Antigens, Human Platelet Epitopes. Acta Paediatr Scand 1983;72(4):583

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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