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Muromonab-CD3

More information in Books or onNLM PubMed
Definition: Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti).  do not coordinate with ANTIBODY FORMATION for biosyn   
Pharmacological Action Immunologic Factors; Immunosuppressive Agents 		Other names Monoclonal Antibody OKT3; OKT3; Ortho Brand of Muromonab CD3; Muromonab CD3; Janssen Brand of Muromonab CD3; Cilag Brand of Muromonab CD3; Orthoclone OKT3; Ortho Brand of Muromonab-CD3; Janssen Brand of Muromonab-CD3; Cilag Brand of Muromonab-CD3Drugs* : ORTHOCLONE OKT3
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hOKT3 gamma4  0   *Muromonab-CD3 Mitogens. Cancer Res 1999 May 1;59(9):2096-101
monoclonal antibody huOKT3(Ala-Ala)  0   *Muromonab-CD3. Transplant Proc 1998 Jun;30(4):1369-70

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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