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Cladribine

More information in Books or onNLM PubMed
Definition: An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.     
Pharmacological Action Antineoplastic Agents; Immunosuppressive Agents 		Other names 2-Chlorodeoxyadenosine; 2-Chloro-2'-deoxyadenosine; Leustatin; 2'-Deoxy-2-chloroadenosineDrugs* : CLADRIBINE; LEUSTATIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
EC regimen 2  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Cladribine. Chemotherapy 2005 Aug;51(5):247-51
CMC protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone Cladribine. Eur J Haematol 2001 Mar;66(3):188-94
CLAG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Granulocyte Colony-Stimulating Factor Cladribine. Leuk Lymphoma. 2000 Sep;39(1-2):121-9
CMD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Mitoxantrone Cladribine. Leuk Lymphoma 1999 Jan;32(3-4):359-63
cladribine triphosphate  0   Adenosine Triphosphate/*analogs & derivatives Cladribine/*analogs & derivatives Ribonucleotide Reductases/antagonists & inhibitors. Blood 1996 Jan 1;87(1):256-64
5'-chloro-5'-deoxyadenosine  892-48-8   *Cladribine Isomerism. J Biol Chem 1985;260(6):3469

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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