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Serotonin Receptor Agonists

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Definition: Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.  general or unspecified; prefer specifics; note entry term SEROTONIN AGONISTS: do not confuse with SEROTONIN ANTAGONISTS   
Examples Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT4 Receptor Agonists
Other names Serotonin Agonists; 5-Hydroxytryptamine Agonists; 5-HT Agonists; Receptor Agonist, Serotonin; Agonists, Serotonin Receptor; Agonists, Serotonin; Agonists, Serotonergic; Agonists, 5-Hydroxytryptamine; Agonists, 5-HT; Agonist, Serotonin Receptor; Agonist, Serotonin; Agonist, Serotonergic; Agonist, 5-Hydroxytrytamine; Agonist, 5-HT; 5 Hydroxytrytamine Agonist; 5 Hydroxytryptamine Agonists; 5 HT Agonists; 5 HT Agonist; Serotonin Receptor Agonist; Serotonin Agonist
Substances having this pharmacologic action: 1-(3-trifluoromethylphenyl)piperazine; 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole; indorenate; gepirone; alpha-methylserotonin; 2,5-dimethoxy-4-bromoamphetamine; Cisapride; Dexfenfluramine; phenyl biguanide; Lisuride; Quipazine; Serotonin; 8-Hydroxy-2-(di-n-propylamino)tetralin; Lysergic Acid Diethylamide; Mescaline; N,N-Dimethyltryptamine; 2,5-Dimethoxy-4-Methylamphetamine; Buspirone; Ergotamine; MK 212; 1-(3-chlorophenyl)piperazine; urapidil; 4-iodo-2,5-dimethoxyphenylisopropylamine; frovatriptan; dimethoxy-4-indophenyl-2-aminopropane; eletriptan; almotriptan; rizatriptan; tegaserod; alnespirone; mosapride; binospirone mesylate; eltoprazine; 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one; 1-(3-chlorophenyl)biguanide; tandospirone; flesinoxan; CGS 12066B; ipsapirone; LY 165163; 5-carboxamidotryptamine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PF 3246799  0   *Azepines *Pyrimidines Serotonin Receptor Agonists Receptor, Serotonin, 5-HT2C. Bioorg Med Chem Lett 2011 May 1;21(9):2715-20
2,4,6-trifluoro-N-(6-((1-methylpiperidin-4-yl)carbonyl)pyridin-2yl)benzamide  0   *Benzamides *Piperidines *Pyridines Serotonin Receptor Agonists. Drug News Perspect. 2010 Sep;23(7):455
2-(1H-imidazol-4-ylmethyl)-8H-indeno(1,2-d)thiazole  0   *Pyrroles *Thiazoles Serotonin Receptor Agonists. Eur J Pharmacol 2000 Dec 8;409(2):195-201
repinotan hydrochloride  0   *Benzopyrans *Thiazoles Serotonin Receptor Agonists. J Pharmacol Exp Ther 1998 Mar;284(3):1082-94
SDZ 219-964  180616-21-1   Organic Chemicals Receptors, Serotonin/agonists Serotonin Receptor Agonists. Psychopharmacology (Berl) 1996 Jun;125(3):231-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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