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Serotonin Receptor Agonists
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Definition
: Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.
general or unspecified; prefer specifics; note entry term SEROTONIN AGONISTS: do not confuse with SEROTONIN ANTAGONISTS
Examples
Serotonin 5-HT1 Receptor Agonists
;
Serotonin 5-HT2 Receptor Agonists
;
Serotonin 5-HT3 Receptor Agonists
;
Serotonin 5-HT4 Receptor Agonists
Other names
Serotonin Agonists; 5-
Hydroxytryptamine Agonists; 5-
HT Agonists; Receptor Agonist, Serotonin; Agonists, Serotonin Receptor; Agonists, Serotonin; Agonists, Serotonergic; Agonists, 5-
Hydroxytryptamine; Agonists, 5-
HT; Agonist, Serotonin Receptor; Agonist, Serotonin; Agonist, Serotonergic; Agonist, 5-
Hydroxytrytamine; Agonist, 5-
HT; 5 Hydroxytrytamine Agonist; 5 Hydroxytryptamine Agonists; 5 HT Agonists; 5 HT Agonist; Serotonin Receptor Agonist; Serotonin Agonist
Substances having this pharmacologic action:
1-(3-trifluoromethylphenyl)piperazine
;
5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole
;
indorenate
;
gepirone
;
alpha-methylserotonin
;
2,5-dimethoxy-4-bromoamphetamine
;
Cisapride
;
Dexfenfluramine
;
phenyl biguanide
;
Lisuride
;
Quipazine
;
Serotonin
;
8-Hydroxy-2-(di-n-propylamino)tetralin
;
Lysergic Acid Diethylamide
;
Mescaline
;
N,N-Dimethyltryptamine
;
2,5-Dimethoxy-4-Methylamphetamine
;
Buspirone
;
Ergotamine
;
MK 212
;
1-(3-chlorophenyl)piperazine
;
urapidil
;
4-iodo-2,5-dimethoxyphenylisopropylamine
;
frovatriptan
;
dimethoxy-4-indophenyl-2-aminopropane
;
eletriptan
;
almotriptan
;
rizatriptan
;
tegaserod
;
alnespirone
;
mosapride
;
binospirone mesylate
;
eltoprazine
;
3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one
;
1-(3-chlorophenyl)biguanide
;
tandospirone
;
flesinoxan
;
CGS 12066B
;
ipsapirone
;
LY 165163
;
5-carboxamidotryptamine
Substance
CAS Registry & name
Categories
Source
Drugs
*
PF 3246799
0
*Azepines
*Pyrimidines
Serotonin Receptor Agonists
Receptor, Serotonin, 5-HT2C.
Bioorg Med Chem Lett 2011 May 1;21(9):2715-20
2,4,6-
trifluoro-
N-
(6-
((1-
methylpiperidin-
4-
yl)carbonyl)pyridin-
2yl)benzamide
0
*Benzamides
*Piperidines
*Pyridines
Serotonin Receptor Agonists.
Drug News Perspect. 2010 Sep;23(7):455
2-
(1H-
imidazol-
4-
ylmethyl)-
8H-
indeno(1,2-
d)thiazole
0
*Pyrroles
*Thiazoles
Serotonin Receptor Agonists.
Eur J Pharmacol 2000 Dec 8;409(2):195-201
repinotan hydrochloride
0
*Benzopyrans
*Thiazoles
Serotonin Receptor Agonists.
J Pharmacol Exp Ther 1998 Mar;284(3):1082-94
SDZ 219-
964
180616-21-1
Organic Chemicals
Receptors, Serotonin/agonists
Serotonin Receptor Agonists.
Psychopharmacology (Berl) 1996 Jun;125(3):231-7