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Receptors, Glutamate

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Definition: Cell-surface proteins that bind glutamate and trigger changes which influence the behavior of cells. Glutamate receptors include ionotropic receptors (AMPA, kainate, and N-methyl-D-aspartate receptors), which directly control ion channels, and metabotropic receptors which act through second messenger systems. Glutamate receptors are the most common mediators of fast excitatory synaptic transmission in the central nervous system. They have also been implicated in the mechanisms of memory and of many diseases.  GEN; prefer specifics; DF: RECEPT GLUTAMATE   
Examples Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate 		Other names Receptors, Excitatory Amino Acid; Glutamate Receptors; Excitatory Amino Acid Receptors; Receptor, Glutamate; Glutamate Receptor; Excitatory Amino Acid Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GluD1 protein, mouse  0   *Receptors, Glutamate Protein Subunits. Biochem Biophys Res Commun. 2012 Jan 6;417(1):157-61
NR1 protein, Xenopus  0   *Receptors, Glutamate *Xenopus Proteins Protein Subunits. Bioorg Khim 1996 Jun;22(6):468-71
GLR3.3 protein, Arabidopsis  0   *Receptors, Glutamate *Arabidopsis Proteins. Plant Physiol 2006 Nov;142(3):963-71
LiGluR receptor  0   *Receptors, Glutamate. Nat Chem Biol 2006 Jan;2(1):47-52
GLR3.4 protein, Arabidopsis  0   *Receptors, Glutamate *Arabidopsis Proteins. Planta 2005 Oct;222(3):418-27
Eat-4 protein, C elegans  0   *Receptors, Glutamate *Caenorhabditis elegans Proteins. J Neurosci 2004 Sep 15;24(37):8135-40
GLR1.1 protein, Arabidopsis  0   *Receptors, Glutamate *Arabidopsis Proteins. Plant Cell Physiol 2004 Oct;45(10):1380-9
alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptor, human  0   *Receptors, Glutamate. J Biol Chem 2004 Oct 1;279(40):41267-70
Slc1a7 protein, rat  0   *Excitatory Amino Acid Transporter 5 Eye Proteins Photoreceptor Cells Receptors, Glutamate.
glutamate receptor III, Drosophila  0   *Receptors, Glutamate *Drosophila Proteins Neuromuscular Junction. J Neurosci 2004 Feb 11;24(6):1406-15
GTRAP41 protein, rat  0   *Spectrin *Receptors, Glutamate. Nature 2001 Mar 1;410(6824):89-93
HG4 protein, Haemonchus contortus  0   *Receptors, Glutamate *Chloride Channels. Mol Biochem Parasitol 1998 Nov 30;97(1-2):177-87
2-amino-4-carboxy-7-(2-naphthyl)hept-6-enoic acid  0   *Glutamates Receptors, Glutamate/agonists. Neuropharmacology 1998 Oct-Nov;37(10-11):1261-7
2-amino-3-(3-(carboxymethoxy)-5-tert-butyl-4-isoxazolyl)propionic acid  0   *Isoxazoles Alanine/*analogs & derivatives Receptors, Glutamate/agonists Receptors, AMPA/antagonists & inhibitors. Neuropharmacology 1998 Oct-Nov;37(10-11):1205-10
glutamate receptor type D  0   *Receptors, Glutamate. Biochem Soc Trans 1997 Aug;25(3):835-8
glutamate receptor delta 1  0   *Receptors, Glutamate. J Neurosci 1997 Jan 15;17(2):834-42
glutamate receptor delta 2  0   *Receptors, Glutamate Zebrafish Proteins. Nature 1997 Aug 21;388(6644):769-73
SLC1A7 protein, human  0   *Excitatory Amino Acid Transporter 5 Eye Proteins Photoreceptor Cells Receptors, Glutamate. Proc Natl Acad Sci U S A 1997 Apr 15;94(8):4155-60
XenU1 protein, Xenopus  0   *Receptors, Glutamate *Xenopus Proteins. Receptors Channels 1996;4(1):31-49
2-amino-4-phosphonobutanoic acid receptor  0   *Receptors, Glutamate. Brain Res 1991 Dec;568(102):15-23
kynurenine receptor  0   *Receptors, Glutamate. Neurosci Biobehav Rev 1983;7(2):107

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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