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Receptors, Interleukin-1

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Definition: Cell surface receptors that are specific for INTERLEUKIN-1. Included under this heading are signaling receptors, non-signaling receptors and accessory proteins required for receptor signaling. Signaling from interleukin-1 receptors occurs via interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88.  DF: RECEPT IL 1 or RECEPT IL1   
Examples Interleukin-1 Receptor Accessory Protein; Receptors, Interleukin-1 Type I; Receptors, Interleukin-1 Type II 		Other names Receptors, IL-1; Interleukin-1 Receptors; IL-1 Receptors; Receptors, Interleukin 1; Receptors, IL1; Receptors, IL 1; Receptor, Interleukin 1; Interleukin 1 Receptors; Interleukin 1 Receptor; IL 1 Receptors; IL1 Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
interleukin-36 receptor, mouse  0   *Receptors, Interleukin-1. J Immunol. 2001 Aug 1;167(3):1440-6.
AMG 108  0   *Antibodies, Monoclonal Receptors, Interleukin-1/antagonists & inhibitors. Arthritis Res Ther 2010;12(5):
TIR8 protein, human  0   *Receptors, Interleukin-1. Trends Immunol 2009 Sep;30(9):439-46
ST2L protein, mouse  0   *Receptors, Interleukin-1. J Immunol. 2008 Jul 1;181(1):62-72
TIRAP protein, mouse  0   *Membrane Glycoproteins *Receptors, Interleukin-1 Signal Transduction.
Tir8 protein, mouse  0   *Receptors, Interleukin-1. Proc Natl Acad Sci U S A 2004 Mar 9;101(10):3522-6
TIRAP protein, human  0   *Membrane Glycoproteins *Receptors, Interleukin-1 Signal Transduction. Nat Immunol 2001 Sep;2(9):835-41
AF 10847  0   *Peptides Receptors, Interleukin-1/antagonists & inhibitors. J Biol Chem 2000 Nov 24;275(47):36927-33
D2S448 protein, human  0   *Antigens, Neoplasm *Receptors, Interleukin-1. Cancer Res 2000 Nov 15;60(22):6448-56; Genomics. 1994 Jul 1;22(1):243-4
TIGIRR-1 receptor  0   *Receptors, Interleukin-1. J Biol Chem 2000 Sep 29;275(39):29946-54
IL36RN protein, human  0   *Interleukins Receptors, Interleukin-1/antagonists & inhibitors. Biochem Biophys Res Commun 1999 Oct 5;263(3):702-6
6-benzylidenehydrazino-1,3-dimethyluracil  0   Uracil/*analogs & derivatives Receptors, Interleukin-1/antagonists & inhibitors. Ophthalmic Res 1998;30(3):180-8
2-benzyl-5-benzylidene-hydrazinopyridazin-3(2H)-one  0   *Hydrazines *Pyridazines Receptors, Interleukin-1/antagonists & inhibitors. Ophthalmic Res 1998;30(3):180-8
5-benzylidenehydrazino-2-phenylpyridazin-3(2H)-one  0   *Hydrazines *Pyridazines Receptors, Interleukin-1/antagonists & inhibitors. Ophthalmic Res 1998;30(3):180-8
5-benzylidenehydrazino-2-methylpyridazin-3(2H)-one  0   *Hydrazines *Pyridazines Receptors, Interleukin-1/antagonists & inhibitors. J Ocul Pharmacol Ther 1998 Feb;14(1):31-44
4-benzylidenehydrazinocoumarin  0   *Coumarins *Hydrazines Receptors, Interleukin-1/antagonists & inhibitors. J Ocul Pharmacol Ther 1998 Feb;14(1):31-44
dihydroepiepoformin  0   *Bicyclo Compounds, Heterocyclic Receptors, Interleukin-1/antagonists & inhibitors. J Antibiot (Tokyo) 1995 Aug;48(8):888-90
IL1RL1 protein, human  0   *Receptors, Cell Surface Receptors, Interleukin-1. Biochim Biophys Acta 1992 Dec 29;1171(2):215-8; EMBO J 1994 Mar 1;13(5):1176-88

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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