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1-Deoxynojirimycin

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Definition: An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.     
Pharmacological Action Antiviral Agents; Enzyme Inhibitors 		Other names 1-Deoxymannojirimycin; 1,5-Deoxy-1,5-imino-D-mannitol; 1 Deoxynojirimycin Hydrochloride; 1 Deoxynojirimycin; 1 Deoxymannojirimycin; Moranoline; Bay n 5595; 1-Deoxynojirimycin Hydrochloride; 1,5-Dideoxy-1,5-imino-D-mannitol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-thio-(5N,6S)-(4-(N'-dansylamino)butyliminomethylidene)nojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Chembiochem. 2010 Nov 22;11(17):2453-64
2,5-imino-2,5-dideoxyfucitol  0   *Sugar Alcohols 1-Deoxynojirimycin/*analogs & derivatives. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7410-3
1-deoxythionojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. J Org Chem. 2010 Oct 1;75(19):6685-8
L-altro-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Org Lett. 2010 Sep 3;12(17):3957-9
D-allo-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Org Lett. 2010 Sep 3;12(17):3957-9
D-galacto-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Org Lett. 2010 Sep 3;12(17):3957-9
N-(8-(3-ethynylphenoxy)octyl)-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Chem Biol Drug Des 2010 Jun;75(6):570-7
DLHex-DGJ  0   1-Deoxynojirimycin/*analogs & derivatives. Mol Genet Metab. 2010 Jul;100(3):262-8
L-1-deoxyallonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. J Org Chem. 2009 Mar 6;74(5):2238-41
L-1-deoxymannojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. J Org Chem. 2009 Mar 6;74(5):2238-41
6-amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Chembiochem 2009 Jun 15;10(9):1480-5
L-deoxyidonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. J Org Chem. 2009 Jun 5;74(11):4309-2
N-methyl-1-deoxynojirimycin-6-phosphate  0   1-Deoxynojirimycin/*analogs & derivatives. J Antibiot (Tokyo). 2006 Aug;59(8):507-11
1,6-dideoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Carbohydr Res 2005 Sep 25;341(13):2200-3
1,4,6-trideoxy-4,4-difluoronojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Org Lett 2005 May 26;7(11):2189-92
deoxynojirimycine  0   Glucosamine/*analogs & derivatives 1-Deoxynojirimycin. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1489-92
glucopyranosyl-(1-3-)-1-deoxymannojirimycin  0   *Glucosides 1-Deoxynojirimycin/*analogs & derivatives. Carbohydr Res 2004 Jul 12;339(10):1823-7
N-(5-adamantane-1-yl-methoxy-pentyl)deoxynojirimycin  0   Adamantane/*analogs & derivatives 1-Deoxynojirimycin/*analogs & derivatives. Int Immunopharmacol 2004 Jul;4(7):939-51
N-pentafluorobenzyl-1-deoxynojirimycin  0   *Benzyl Compounds 1-Deoxynojirimycin/*analogs & derivatives. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3789-92
1-deoxy-D-galactohomonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Org Chem 2004 Apr 2;69(7);2229-34
1-deoxygalactonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives alpha-Galactosidase/antagonists & inhibitors. Chembiochem 2003 Apr 4;4(4):260-4
fuconojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Angew Chem Int Ed Engl. 2003 Oct 6;42(38):4657-60
1-deoxy-talonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Carbohydr Res 2002 Jun 12;337(12):1083-7
1-deoxy-gulonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Carbohydr Res 2002 Jun 12;337(12):1083-7
1-deoxy-5-dehydroxymethyl-nojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Bioorg Med Chem 2002 Jul;10(7):2150-60
6-deoxymannojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Carbohydr Res 2001 Jun 15;332(4):351-61
N-stearoyl-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Bioorg Med Chem Lett 2000 May 15;10(10):1011-4
N-(3'-iodo-2'-propenyl)-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Nucl Med Biol 1999 Oct;26(7):833-9
N-(3'-iodobenzyl)-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Nucl Med Biol 1999 Oct;26(7):833-9
1-deoxy-3-O-(5-thioglucopyranosyl)mannojirimycin  0   *Glucosides 1-Deoxynojirimycin/*analogs & derivatives Mannosidases/antagonists & inhibitors. Bioorg Med Chem Lett 1998 May 19;8(10):1215-20
1-deoxy-3-S-(1-thioglucopyranosyl)mannojirimycin  0   *Glucosides 1-Deoxynojirimycin/*analogs & derivatives Mannosidases/antagonists & inhibitors. Bioorg Med Chem Lett 1998 May 19;8(10):1215-20
N-nonyl-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives alpha-Glucosidases/antagonists & inhibitors. Nat Med 1998 May;4(5):610-4
rhamno-1-deoxynojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Chirality 1998;10(1-2):88-90
N-methylhomonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. Glycobiology 1997 Mar;7(2):297-304
homonojirimycin  119557-99-2   1-Deoxynojirimycin/*analogs & derivatives. Glycobiology 1997 Mar;7(2):297-304
3-O-galactopyranoylmoranoline  0   1-Deoxynojirimycin/*analogs & derivatives. Biosci Biotechnol Biochem 1996 Apr;60(4):694-6
4-O-galactopyranosylmoranoline  0   1-Deoxynojirimycin/*analogs & derivatives. Biosci Biotechnol Biochem 1996 Apr;60(4):694-6
nojirimycin tetrazole  0   Tetrazoles 1-Deoxynojirimycin/*analogs & derivatives. Biochemistry 1996 Jun 11;35(23):7341-55
homomannojirimycin  127995-29-3   1-Deoxynojirimycin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1995 Mar;43(3):414-20
N-butyldeoxygalactonojirimycin  0   1-Deoxynojirimycin/*analogs & derivatives. J Biol Chem 1994 Oct 28;269(43):27108-14
N-pentyl-1-deoxynojirimycin  121133-60-6   1-Deoxynojirimycin/*analogs & derivatives Glucosidases/antagonists & inhibitors. J Leukoc Biol 1994 Aug;56(2):159-65
N-(3-phenyl-2-propenyl)-1-deoxynojirimycin  73243-68-2   1-Deoxynojirimycin/*analogs & derivatives. Jpn J Med Sci Biol 1991;43(3):75
N-(5'-carboxypentyl)-1-deoxynojirimycin  79206-51-2   1-Deoxynojirimycin/*analogs & derivatives. Biochem J 1990;270(2):539
deoxyfuconojirimycin  99212-30-3   *Sugar Alcohols 1-Deoxynojirimycin/*analogs & derivatives alpha-L-Fucosidase/antagonists & inhibitors. Biochem J 1990;265(1):277
miglustat  0   1-Deoxynojirimycin/*analogs & derivatives Gaucher Disease alpha-Glucosidases/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors ; Anti-HIV Agents 		Am Fam Physician 1989;39(6):330ZAVESCA
4-O-glucopyranosylmoranoline  80312-32-9   1-Deoxynojirimycin/*analogs & derivatives alpha-Glucosidases/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1989;37(1):106
nojirimycin 6-phosphate  116026-31-4   1-Deoxynojirimycin/*analogs & derivatives Glucose-6-Phosphate/*analogs & derivatives Phosphoglucomutase/antagonists & inhibitors. Biochemistry 1988;27(19):7328
2-acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol  105265-96-1   1-Deoxynojirimycin/*analogs & derivatives Acetylglucosaminidase/antagonists & inhibitors. Carbohydr Res 1987;164:141
N,N-dimethyldeoxynojirimycin  104195-23-5   1-Deoxynojirimycin/*analogs & derivatives. Biochim Biophys Acta 1985;825(2):95
emiglitate  80879-63-6   1-Deoxynojirimycin/*analogs & derivatives.
Pharma Action Anti-Bacterial Agents 		Digestion 1985;31(2-3):120
miglitol  72432-03-2   1-Deoxynojirimycin/*analogs & derivatives alpha-Glucosidases/antagonists & inhibitors Anti-Bacterial Agents.
Pharma Action Enzyme Inhibitors ; Hypoglycemic Agents 		Digestion 1985;31(2-3):120GLYSET
N-methyldeoxynojirimycin  69567-10-8 D-Glucitol, 1,5-dideoxy-1,5-(methylimino)  1-Deoxynojirimycin/*analogs & derivatives.
Pharma Action Anti-Bacterial Agents ; Antiviral Agents ; Enzyme Inhibitors 		Dtsch Zahnaerztl Z 1981;36(12):841
nojirimycin  15218-38-9   1-Deoxynojirimycin/*analogs & derivatives Sucrase/antagonists & inhibitors.
Pharma Action Anti-Bacterial Agents ; Enzyme Inhibitors 		Biochim Biophys Acta 525(1):142;1978; J Antibiot (Tokyo) 29(10):1007;1976; J Biochem 81:1017;1977

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