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ψ
ψ
Proton Pumps
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Definition
: Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
/antag - consider also POTASSIUM HYDROGEN ATPASE /antag
Examples
Bacteriorhodopsins
;
Electron Transport Complex I
;
Electron Transport Complex III
;
Electron Transport Complex IV
;
Inorganic Pyrophosphatase
;
Photosystem I Protein Complex
;
Proton-Translocating ATPases
Other names
H(+) Pump; Pumps, Proton; Pump, Proton; Pump, H+; Proton Pump; H+ Pump
Substance
CAS Registry & name
Categories
Source
Drugs
*
IPP2 protein, S cerevisiae
EC 3.6.1.1
*Proton Pumps
*Saccharomyces cerevisiae Proteins.
Proc Natl Acad Sci U S A 2002 Dec 10;99(25):15914-9
1-
(2-
methyl-
4-
methoxyphenyl)-
4-
((2-
hydroxyethyl)amino)-
6-
trifluoromethoxy-
2,3-
dihydropyrrolo(3,2-
c)quinoline
0
*Pyrroles
*Quinolines
Proton Pumps/antagonists & inhibitors.
Arch Pharm Res. 2001 Jun;24(3):207-10
YJA 20379-
5
0
*Benzimidazoles
*Thiazoles
Proton Pumps/antagonists & inhibitors.
Arch Pharm Res 1998 Jun;21(3):241-7
YJA 20379-
8
0
*Naphthyridines
Proton Pumps/antagonists & inhibitors.
Res Commun Mol Pathol Pharmacol 1998 May;100(2):187-200
YJA 20379-
1
0
*Imidazoles
*Benzothiazoles
Proton Pumps/antagonists & inhibitors.
Res Commun Mol Pathol Pharmacol 1997 Oct;98(1):77-84
BY 841
0
*Imidazoles
*Pyridines
Proton Pumps/antagonists & inhibitors
H(+)-K(+)-Exchanging ATPase/antagonists & inhibitors.
Yale J Biol Med 1996 May-Jun;69(3):233-43
htrI protein, Halobacterium salinarium
0
*Membrane Proteins
*Archaeal Proteins
Halobacterium
Proton Pumps.
J Biol Chem 1993 Aug 5;268(22):16095-7
lansoprazole
103577-45-3
*2-Pyridinylmethylsulfinylbenzimidazoles
Proton Pumps/antagonists & inhibitors
H(+)-K(+)-Exchanging ATPase/antagonists & inhibitors.
Pharma Action
Anti-Infective Agents
;
Anti-Ulcer Agents
;
Enzyme Inhibitors
J Pharmacol Exp Ther 1989;248(2):799
PREVACID
;
LANSOPRAZOLE
;
PREVACID NAPRAPAC 250 (COPACKAGED)
;
PREVACID NAPRAPAC 375 (COPACKAGED)
;
PREVACID IV
;
DEXILANT
;
PREVACID 24 HR
;
PREVACID NAPRAPAC 500 (COPACKAGED)