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Gap Junctions

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Definition: Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of CONNEXINS, the family of proteins which form the junctions.  intercellular junctions; A 11 qualif except /cytol /transpl; /genet permitted   
See Also Connexins
Examples Electrical Synapses 		Other names Junctions, Gap; Junction, Gap; Gap Junction
 
SubstanceCAS Registry & nameCategoriesSource
INX-16 protein, C elegans  0   *Connexins *Caenorhabditis elegans Proteins Gap Junctions Protein Subunits. Curr Biol 2007 Sep 18;17(18):1601-8
pannexin 3, rat  0   *Nerve Tissue Proteins Gap Junctions. Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13644-9
pannexin 2, rat  0   *Connexins Gap Junctions. Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13644-9
pannexin 1, rat  0   *Nerve Tissue Proteins *Connexins Gap Junctions. Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13644-9
GJD3 protein, human  0   *Connexins Gap Junctions. J Biol Chem 2002 Oct 11;277(41):38272-83
connexin 47  0   *Connexins Gap Junctions. J Neurosci 2001 Feb 15;21(4):1117-26
18alpha-glycyrrhetinic acid  1449-05-4   Glycyrrhetinic Acid/*analogs & derivatives Gap Junctions. Gastroenterology 1999 May;116(5):1176-83

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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