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Connexins

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Definition: A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.     
Examples Connexin 43 		Other names Gap Junction Proteins; Junction Proteins, Gap; Junction Protein, Gap; Gap Junction Protein; Gap Junction Channel Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pannexin 1 protein, Xenopus  0   *Connexins *Xenopus Proteins. J Membr Biol. 2011 Nov;244(1):21-33
connexin 31, mouse  0   *Connexins. Protein Cell 2010 Oct;1(10):935-43
GJA10 protein, human  0   *Connexins.
Cx40.8 protein, zebrafish  0   *Connexins *Zebrafish Proteins. FEBS Lett 2009 Nov 3;583(21):3419-24
Panx1 protein, zebrafish  0   *Connexins *Zebrafish Proteins. Neuroscience 2009 Sep 15;162(4):1039-54
pannexin 3 protein, mouse  0   *Connexins. J Cell Sci 2007 Nov 1;120(Pt 21):3772-83
Ecx protein, zebrafish  0   *Connexins *Zebrafish Proteins. Proc Natl Acad Sci U S A 2008 Mar 25;105(12):4763-8
INX-16 protein, C elegans  0   *Connexins *Caenorhabditis elegans Proteins Gap Junctions Protein Subunits. Curr Biol 2007 Sep 18;17(18):1601-8
NSY-5 protein, C elegans  0   *Connexins *Caenorhabditis elegans Proteins. Cell 2007 May 18;129(4):787-99
Panx2 protein, mouse  0   *Connexins. Genomics 2004 Apr;83(4):706-16
Cx29 protein, Xenopus  0   *Connexins *Xenopus Proteins. Biochem Biophys Res Commun 2006 Oct 20;349(2):855-62
Cx28.6 protein, Xenopus  0   *Connexins *Xenopus Proteins. Biochem Biophys Res Commun 2006 Oct 20;349(2):855-62
connexin 30.2, mouse  0   *Connexins. FEBS Lett 2003 Apr 10;540(1-3):151-6
connexin 30, rat  0   *Connexins. Cell Tissue Res 1998 Dec;294(3):415-20
connexin 29, rat  0   *Connexins. Biochem Biophys Res Commun 2005 Dec 16;338(2):723-8
connexin 39, rat  0   *Connexins. Cell Tissue Res 2005 May;320(2):299-310
connexin 40.4 protein, Xenopus  0   *Connexins *Xenopus Proteins. Dev Dyn 2005 Jul;233(3):864-71
Panx1 protein, mouse  0   *Nerve Tissue Proteins *Connexins. Eur J Neurosci. 2005 Jun;21(12):3277-90
connexin 39 protein, mouse  0   *Connexins. J Cell Sci. 2004 Oct 15;117(Pt 22):5381-92
PANX3 protein, human  0   *Connexins. Genomics 2004 Apr;83(4):706-16
PANX2 protein, human  0   *Connexins. Genomics 2004 Apr;83(4):706-16
PANX1 protein, human  0   *Connexins *Nerve Tissue Proteins. Genomics 2004 Apr;83(4):706-16
GJB6 protein, human  0   *Connexins.
Cx30 protein, Xenopus  0   *Connexins *Xenopus Proteins.
gja9 protein, zebrafish  0   *Eye Proteins *Connexins *Zebrafish Proteins.
connexin 48.5, zebrafish  0   *Connexins *Zebrafish Proteins. Dev Dyn 2003 Dec;228(4):709-15
Cx46 protein, rat  0   *Connexins. J Gen Physiol. 2003 Oct;122(4):389-405
cx55.5 protein, zebrafish  0   *Connexins *Zebrafish Proteins.
connexin 45.6, zebrafish  0   *Connexins *Zebrafish Proteins. Am J Physiol Heart Circ Physiol 2004 May;286(5):H1623-32
GJD4 protein, human  0   *Connexins. Cell Commun Adhes 2003 Jan-Feb;10(1):27-36
Cx52.6 protein, zebrafish  0   *Connexins *Zebrafish Proteins. J Biol Chem 2004 Jan 23;279(4):2913-21
pannexin 2, rat  0   *Connexins Gap Junctions. Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13644-9
pannexin 1, rat  0   *Nerve Tissue Proteins *Connexins Gap Junctions. Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13644-9
connexin 43alpha1, mouse  0   *Connexins. Cell Commun Adhes 2001;8(4-6):289-92
GJB7 protein, human  0   *Connexins. Cell Commun Adhes 2001;8(4-6):167-71
GJD3 protein, human  0   *Connexins Gap Junctions. J Biol Chem 2002 Oct 11;277(41):38272-83
GJC3 protein, human  0   *Nerve Tissue Proteins *Connexins. J Neurosci 2002 Aug 1;22(15):6458-70
Gje1 protein, mouse  0   *Nerve Tissue Proteins *Connexins. J Neurosci 2002 Aug 1;22(15):6458-70
Zpg protein, Drosophila  0   *Connexins *Drosophila Proteins. Development 2002 May;129(10):2529-39
gap 27 peptide  0   *Connexins. Circ Res 2002 May 31;90(10):1108-13
GJA9 protein, human  0   *Connexins. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002 Apr;19(2):95-9)
INX3 protein, Drosophila  0   *Connexins *Drosophila Proteins.
connexin 32.3, Pagrus major  0   *Connexins *Fish Proteins. Comp Biochem Physiol B Biochem Mol Biol 2001 Jul;129(4):767-75
connexin 44  0   *Connexins. J Membr Biol 2001 May 1;181(1):21-30
connexin 47  0   *Connexins Gap Junctions. J Neurosci 2001 Feb 15;21(4):1117-26
connexin 31.5  0   *Connexins. J Exp Biol 2000 Nov;203 Pt 21:3299-306
connexin 36  0   *Connexins. Gene 2000 Jun 27;251(2):123-30
inx2 protein, Drosophila  0   *Connexins *Drosophila Proteins. Gene 1999 May 31;232(2):191-201
inx7 protein, Drosophila  0   *Connexins *Drosophila Proteins. Gene 1999 May 31;232(2):191-201
INX6 protein, Drosophila  0   *Connexins *Drosophila Proteins. Gene 1999 May 31;232(2):191-201
Gja10 protein, mouse  0   *Connexins. J Biol Chem 1999 May 21;274(21):14716-23
connexin 34.7 protein, Morone americana  0   *Connexins *Fish Proteins. J Neurosci 1998 Oct 1;18(19):7625-37
connexin 49 protein, Ovis aries  0   *Connexins. Dev Biol 1997 Nov 1;191(1):88-102
connexin 38  121127-32-0   *Connexins. Biophys J 1996 Aug;71(2):742-8
eat-5 protein, C elegans  0   *Connexins *Caenorhabditis elegans Proteins. J Cell Biol 1996 Jul;134(2):537-48
Gjb6 protein, mouse  0   *Connexins. J Biol Chem 1996 Jul 26;271(30):17903-10
connexin 35 protein, vertebrate  0   *Connexins Eye Proteins. Mol Biol Cell 1996 Feb;7(2):233-43
Gja6 protein, rat  145717-22-2   *Connexins. Dev Biol 1996 Apr 10;175(1):50-6
connexin 41, Xenopus  0   *Connexins *Xenopus Proteins. Mol Reprod Dev 1995 Sep;42(1):7-18
connexin 26  127120-53-0   *Connexins.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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