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Organosilicon Compounds

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Definition: Organic compounds that contain silicon as an integral part of the molecule.  DF: ORGANOSILICON CPDS   
Examples Silanes; Siloxanes; Trimethylsilyl Compounds
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
polysilsesquioxane  0   *Organosilicon Compounds. Angew Chem Int Ed Engl. 2011 Oct 24;50(44):10330-4
2,3,4,5-tetraethylsilole dianion (SiC4Et4)(2).2(Li)+  0   *Organosilicon Compounds. Molecules. 2011;16(9) (dup#20):8033-40
1-bromo-1-silacyclopentane  0   *Cyclopentanes *Organosilicon Compounds. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):858-66
dithieno(3,2-b-2',3'-d)silole  0   *Organosilicon Compounds. J Am Chem Soc. 2011 Mar 30;133(12):4250-3
1,1-bis(trimethylsilyl)-2-dimethylamino-2-trimethylsiloxysilane  0   *Organosilicon Compounds. Dalton Trans 2010 Oct 21;39(39):9379-85
N,N-dimethyl(tris(trimethylsilyl)silyl)methaneamide  0   *Organosilicon Compounds. Dalton Trans 2010 Oct 21;39(39):9379-85
UK 101  0   *Dipeptides *Organosilicon Compounds. J Phys Chem B 2010 Sep 30;114(38):12333-9
N-tert-butyloxycarbonylpyrrolidine-2-carboxylic acid (2'-(4-trimethoxysilylbenzylamide)cyclohexyl)amide  0   *Organosilicon Compounds Proline/*analogs & derivatives. Chemistry 2010 Jul 12;16(26):7852-8
bis(mu3-1,8-bis(triisopropylsilylamido)naphthalene)bis(tetrahydrofuran)di-mu3-oxidodimanganese(III)  0   *Organosilicon Compounds *Coordination Complexes Manganese. Acta Crystallogr C 2010 Aug;66(Pt 8):m204-6
per-O-tert-butyldimethylsilyl-beta-D-galactofuranose  0   *Organosilicon Compounds Galactose/*analogs & derivatives. J Org Chem. 2009 Mar 6;74(5):1994-2003
poly((4,4-didodecyldithieno(3,2-b-2,3-d)silole)-2,6-diyl-alt-(2,1,3-benoxadiazole)-4,7-diyl)  0   *Oxadiazoles *Organosilicon Compounds. Adv Mater 2010 Feb 23;22(8):E63-6
1,2-disilacyclohexene  0   *Organosilicon Compounds. J Am Chem Soc. 2010 Apr 14;132(14):5008-9
octakis(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)-gamma-cyclodextrin  0   *Organosilicon Compounds *gamma-Cyclodextrins. J Mol Graph Model 2010 Feb 26;28(6):506-12
silacaptopril  0   *Organosilicon Compounds Captopril/*analogs & derivatives Ligands. J Pept Sci 2010 Feb;16(2):91-7
1-silyl-1-silacyclohexane  0   *Organosilicon Compounds. J Phys Chem A. 2010 Feb 11;114(5):2127-35
sila-haloperidol  0   *Organosilicon Compounds Haloperidol/*analogs & derivatives. Drug Metab Dispos 2010 Jan;38(1):73-83
m-trifluoromethyl-diphenyl diselenide  0   *Organosilicon Compounds. Behav Brain Res. 2009 Dec 28;205(2):511-7
1-dimethylamino-3-silyloxy-1,3-butadiene  0   *Organosilicon Compounds. Chem Commun (Camb). 2009 Dec 21;(47):7294-6
disila-AM580  0   *Organosilicon Compounds 4-Aminobenzoic Acid/*analogs & derivatives. ChemMedChem 2009 Nov;4(11):1797-802
disila-tamibarotene  0   *Phthalic Acids *Organosilicon Compounds. ChemMedChem 2009 Nov;4(11):1797-802
AC3056  0   *Organosilicon Compounds. J Sex Med. 2009 Feb;6(2):373-87
Na-kanemite  0   *Organosilicon Compounds. J Hazard Mater. 2009 Jul 30;166(2-3):1550-5
Na-magadiite  0   *Organosilicon Compounds. J Hazard Mater. 2009 Jul 30;166(2-3):1550-5
divinylsilyl-11-silicotungstic acid  0   *Silicates *Organosilicon Compounds *Tungsten Compounds. ChemSusChem 2009;2(3):226-9
octa(3-aminopropyl)octasilsequioxane octahydrochloride  0   *Organosilicon Compounds. Chemistry 2009;15(22):5436-40
3-(tert-butyldimethylsilyloxy)-1-cyanoallyl diisopropylcarbamate  0   *Carbamates *Organosilicon Compounds. Chemistry 2009;15(14):3363-6
3-(tert-butyldimethylsilyl)-1-cyano-3-hydroxyprop-1-enyl carbamate  0   *Carbamates *Organosilicon Compounds. Chemistry 2009;15(14):3363-6
4-(di-tert-butyl(18F)fluorosilyl)benzenethiol  0   *Organosilicon Compounds Positron-Emission Tomography. Bioconjug Chem 2009 Feb;20(2):317-21
UVM-7 compound  0   *Organosilicon Compounds. Chemistry. 2008;14(27):8267-78
titanosilsesquioxane  0   *Organosilicon Compounds Titanium. Chemistry. 2008;14(27):8098-101
polymethylsilsesquioxane  0   *Polymers *Organosilicon Compounds. J Phys Chem B 2006 Aug 17;110(32):15887-95
O(6)-allyl-3',5'-di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine  0   *Organosilicon Compounds Deoxyguanosine/*analogs & derivatives. J Org Chem 2007 Dec 21;72(26):9983-90
p-(di-tert-butyl((18)F)fluorosilyl)benzaldehyde  0   *Organosilicon Compounds. Bioconjug Chem 2007 Nov-Dec;18(6):2085-9
4-(2-(3,5,5,8,8-pentamethyl-5,8-disila-5,6,7,8-tetrahydro-2-naphthalenyl)-1-propenyl)benzoic acid  0   *Organosilicon Compounds *Benzoic Acids. Chembiochem 2007 Sep 24;8(14):1688-99
4-(2-(5,5,8,8-tetramethyl-5,8-disila-5,6,7,8-tetrahydro-2-naphthalenyl)-1-propenyl)benzoic acid  0   *Organosilicon Compounds *Benzoic Acids. Chembiochem 2007 Sep 24;8(14):1688-99
octakis(3-(3-amino-1,2,4-triazole)propyl)octasilsesquioxane  0   *Organosilicon Compounds. J Colloid Interface Sci 2007 Dec 15;316(2):250-9
polyphenylsilsesquioxane  0   *Organosilicon Compounds. J Nanosci Nanotechnol. 2007 Sep;7(9):3307-12
diphenyldimethoxysilane  0   *Organosilicon Compounds. Analyst 2007 Mar;132(3):224-9
1-methyl-3-(3-(trimethoxy-lambda(4)-silyl)propyl)imidazolium iodide  0   *Organosilicon Compounds. J Phys Chem B 2005 Aug 4;109(30):14387-95
bis(triisopropylsilylethynyl)pentacene  0   *Organosilicon Compounds. J Phys Chem B 2006 Aug 24;110(33):16397-403
polyhedraloligosilsesquioxane  0   *Organosilicon Compounds. J Oral Rehabil 2007 May;34(5):389-95
(2-(3,4-epoxycyclohexyl)ethyl)heptaisobutyloctasilsesquioxane  0   *Organosilicon Compounds. Langmuir 2006 Apr 11;22(8):3633-9
10-amine-4-azadecylsilica  0   *Amines *Organosilicon Compounds. J Colloid Interface Sci 2006 Oct 15;302(2):396-407
7-amine-4-azaheptylsilica  0   *Amines *Organosilicon Compounds. J Colloid Interface Sci 2006 Oct 15;302(2):396-407
1,3-disilacyclobutane  0   *Cyclobutanes *Organosilicon Compounds. J Phys Chem A Dyn Kinet Environ Chem Spectrosc Struct Theory 2007 Feb 8;111(5):825-31
5'-tert-butyl-dimethylsilyl-2',3'-O-isopropylidene guanosine  0   *Organosilicon Compounds Guanosine/*analogs & derivatives. Chem Commun (Camb) 2005 Sep 14;(34):4294-6
silicon tribenzonaphthoporphyrazate  0   *Organosilicon Compounds. Photomed Laser Surg 2006 Oct;24(5):581-7
BAM-SiPc  0   *Indoles *Organosilicon Compounds. Cancer Biol Ther 2006 Apr;5(4):413-8
2,5-di-(3-biphenyl)-1,1-dimethyl-3,4-diphenylsilole  0   *Organosilicon Compounds. J Chem Phys 2004 Nov 8;121(18):9031-8
2,5-bis(6'-(2',2''-bipyridyl))-1,1-dimethyl-3,4-diphenylsilole  0   *Organosilicon Compounds. J Chem Phys 2004 Nov 8;121(18):9031-8
tris(trimethylsiloxy)silylstyrene homopolymer  0   *Organosilicon Compounds. J Colloid Interface Sci 2005 Oct 1;290(1):91-101
1,3-bis(1,1,3,3,5,5-hexaethoxy-1,3,5-trisilacyclohexyl)propane  0   *Organosilicon Compounds. Angew Chem Int Ed Engl 2005 Mar 29;44(14):2107-9
bis(trimethoxysilylpropyl)amine  0   *Propylamines *Organosilicon Compounds. Colloids Surf B Biointerfaces 2006 Apr 15;49(1):55-9
bis(4-(4-acetylpiperazine)phenoxy)phthalocyaninatosilicon  0   *Organosilicon Compounds. Bioorg Med Chem Lett. 2006 May 1;16(9):2450-3
trisilanolisobutyl-POSS  0   *Organosilicon Compounds. Langmuir. 2005 Mar 1;21(5):1908-16
phenyldimethylsilyllithium  0   *Organometallic Compounds *Organosilicon Compounds Lithium. Org Biomol Chem 2004 Oct 21;2(20):3006-17
cyclohexanediol isobutyl-polyhedral oligomeric silsesquioxane  0   *Organosilicon Compounds. Biomacromolecules 2006 Jan;7(1):215-23
poly(gamma-aminopropyl triethoxysilane)  0   *Organosilicon Compounds. Langmuir. 2004 Jan 6;20(1):273-5
3-(trimethoxysilyl)propyl methacrylate  0   *Methacrylates *Organosilicon Compounds. J Am Chem Soc. 2005 Sep 21;127(37):12800-1
polyhedral oligomeric silsesquioxane methacrylate  0   *Methacrylates *Organosilicon Compounds. Dent Mater 2005 Jun;21(6):520-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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