Definition: A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. They are found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Other names Tumor Necrosis Factor Receptor Superfamily, Member; Ki-1 Antigens; CD30 Antigens; Ber-H2 Antigens; Antigens, Ki-1; Receptor, TNFRSF8; Ki 1 Antigens; Ki 1 Antigen; Ber H2 Antigens; Ber H2 Antigen; Antigens, Ki 1; Antigens, Ber-H2; Antigen, Ki-1; Antigen, CD30; Antigen, Ber-H2; TNFRSF8 Receptor; Ki-1 Antigen; CD30 Antigen; Ber-H2 Antigen
