encyclopedia of medical concepts
ψ 
ψ 
ψ 

Antiporters

More information in Books or onNLM PubMed
Definition: Membrane transporters that co-transport two or more dissimilar molecules in the opposite direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.     
Examples Anion Exchange Protein 1, Erythrocyte; Chloride-Bicarbonate Antiporters; Potassium-Hydrogen Antiporters; Reduced Folate Carrier Protein; Sodium-Calcium Exchanger; Sodium-Hydrogen Antiporter; Sodium-Potassium-Exchanging ATPase; Vesicular Neurotransmitter Transport Proteins 		Other names Exchange Proteins, Cation; Exchange Proteins, Anion; Cation Exchangers (Proteins); Anion Exchangers (Proteins); Cation Exchange Proteins; Anion Exchange Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CHX23 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10211-6.
CLC-ec1 protein, E coli  0   *Antiporters *Escherichia coli Proteins. J Gen Physiol. 2004 Feb;123(2):109-19.
Slc37a2 protein, human  0   *Antiporters. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E110-20.
NCKX4 protein, mouse  0   *Antiporters. Nat Neurosci. 2012 Jan;15(1):131-7
CCX5 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Biochem Biophys Res Commun. 2011 Oct 14;414(1):96-100.
Gex1 protein, S cerevisiae  0   *Antiporters *Saccharomyces cerevisiae Proteins. Mol Biol Cell. 2011 Jun 15;22(12):2054-67.
CAX1 protein, zebrafish  0   *Antiporters *Zebrafish Proteins. Biochemistry 2010 Aug 10;49(31):6557-66
Letm1 protein, Drosophila  0   *Calcium-Binding Proteins *Antiporters *Drosophila Proteins Mitochondrial Proteins. Science. 2009 Oct 2;326(5949):144-7
Slc26a9 protein, mouse  0   *Antiporters. Proc Natl Acad Sci U S A 2008 Nov 18;105(46):17955-60
ClcA protein, E coli  0   *Antiporters *Escherichia coli Proteins. J Mol Biol 2008 Sep 12;381(4):860-6
NHA2 protein, human  0   *Antiporters. Bone 2008 Jan;42(1):180-92
NHA2 protein, mouse  0   *Antiporters. Gene Expr Patterns 2007 Oct;7(8):846-51
MATE2 protein, mouse  0   *Antiporters *Organic Cation Transport Proteins. Am J Physiol Cell Physiol 2007 Nov;293(5):C1437-44
Slc26a8 protein, mouse  0   *Antiporters *Anion Transport Proteins. Hum Mol Genet. 2007 Aug 1;16(15):1783-93
BOR4 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Science. 2007 Nov 30;318(5855):1417
CHX20 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Plant Physiol 2004 Sep;136(1):2532-47
small multidrug-resistance pump, Staphylococcus aureus  0   *Antiporters Drug Resistance, Multiple. J Biol Chem 1994 Nov 25;269(47):29998-30004
NHX8 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Plant J 2007 Feb;49(4):718-28
TAAC protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. J Biol Chem 2007 Mar 23;282(12):8848-59
citrate-isocitrate carrier, rat  0   *Antiporters *Organic Anion Transporters. J Biol Chem 2006 Nov 24;281(47):35624-32
MATE1 protein, rat  0   *Antiporters *Organic Cation Transport Proteins. Drug Metab Dispos 2006 Nov;34(11):1868-74
G6PT1 protein, rat  0   *Monosaccharide Transport Proteins *Antiporters. J Nutr 2006 Sep;136(9):2308-13
SLC24A5 protein, human  0   *Antiporters. Science. 2005 Dec 16;310(5755):1754-5
SLC24A5 protein, zebrafish  0   *Antiporters *Zebrafish Proteins. Science. 2005 Dec 16;310(5755):1754-5
CAX3 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Plant Physiol 2005 Aug;138(4):2048-60
Slc37a4 protein, rat  0   *Monosaccharide Transport Proteins *Antiporters.
Slc37a4 protein, mouse  0   *Monosaccharide Transport Proteins *Antiporters.
SLC37A4 protein, human  0   *Monosaccharide Transport Proteins *Antiporters.
Slc4a1ap protein, mouse  0   *Antiporters.
mdtK protein, E coli  0   *Antiporters *Escherichia coli Proteins.
NDAE1 protein, Drosophila  0   *Antiporters *Drosophila Proteins. Dev Biol 2004 Aug 15;272(2):419-31
xasA protein, E coli  0   *Membrane Proteins *Escherichia coli Proteins Antiporters.
CadB protein, E Coli  0   *Antiporters *Amino Acid Transport Systems *Escherichia coli Proteins.
Slc26a3 protein, rat  0   *Antiporters Bicarbonates Chlorides Transcription Factors.
Slc26a3 protein, mouse  0   *Antiporters Bicarbonates Chlorides Transcription Factors.
Slc4a3 protein, rat  0   *Antiporters.
SLC4A3 protein, human  0   *Antiporters.
SLC25A24 protein, human  0   *Calcium-Binding Proteins *Antiporters *Mitochondrial Proteins. J Biol Chem 2004 Jun 4;279(23):24701-13
Slc26a7 protein, rat  0   *Antiporters.
TetL protein, Bacillus subtilis  0   *Bacterial Proteins *Antiporters Tetracycline Resistance. Biochemistry. 2003 Dec 2;42(47):13969-76
Slco4a1 protein, rat  0   *Eye Proteins *Antiporters *Organic Anion Transporters. Invest Ophthalmol Vis Sci 2003 Nov;44(11);4877-84
YjdE protein, E coli  0   *Antiporters *Amino Acid Transport Systems *Escherichia coli Proteins. J Bacteriol 2003 Aug;185(15):4402-9
TPO1 protein, S cerevisiae  0   *Antiporters *Organic Cation Transport Proteins *Saccharomyces cerevisiae Proteins. J Biol Chem 2003 Apr 11;278(15):12820-5
SLC24A4 protein, human  0   *Antiporters. J Biol Chem 2002 Dec 13;277(50):48410-7
CaiT protein, E coli  0   *Antiporters *Escherichia coli Proteins. Mol Microbiol 1994 Sep;13(5):775-86
BOR1 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Nature 2002 Nov 21;420(6913):282-3
Slc26a1 protein, mouse  0   *Antiporters *Anion Transport Proteins. Am J Physiol Renal Physiol 2002 Oct;283(4):F826-38
Slc26a6 protein, mouse  0   *Antiporters. Am J Physiol Renal Physiol 2002 Oct;283(4):F826-38
CadA protein, Vibrio vulnificus  0   *Bacterial Proteins *Antiporters. FEMS Microbiol Lett 2002 Mar 5;208(2):245-51
CAX4 protein, Arabidopsis  0   *Antiporters *Arabidopsis Proteins. Plant Physiol 2002 Apr;128(4):1245-54
SLC26A9 protein, human  0   *Antiporters. J Biol Chem 2002 Apr 19;277(16):14246-54
SLC26A8 protein, human  0   *Antiporters *Anion Transport Proteins. J Biol Chem 2002 Apr 19;277(16):14246-54
SLC26A7 protein, human  0   *Antiporters. J Biol Chem 2002 Apr 19;277(16):14246-54
VmrA protein, Vibrio parahaemolyticus  0   *Bacterial Proteins *Antiporters. J Bacteriol 2002 Jan;184(2):572-6
GadC protein, Listeria  0   *Bacterial Proteins *Antiporters. Mol Microbiol 2001 Apr;40(2):465-75
SLC4A11 protein, human  0   *Antiporters *Anion Transport Proteins. Biochem Biophys Res Commun 2001 Apr 20;282(5):1103-9
Tet(L) protein, E coli  0   *Antiporters *Escherichia coli Proteins Tetracycline Resistance. J Bacteriol 2001 Apr;183(8):2667-71
GerN protein, Bacillus cereus  0   *Bacterial Proteins *Antiporters. J Bacteriol 2001 Jan;183(2):476-82
MLEN protein, Bacillus subtilis  0   *Bacterial Proteins *Antiporters *Cation Transport Proteins. J Biol Chem 2000 Sep 29;275(39):30287-92
Tim18 protein, S cerevisiae  0   *Antiporters *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2000 Feb;20(4):1187-93
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy