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Myogenic Regulatory Factors

More information in Books or onNLM PubMed
Definition: A family of muscle-specific transcription factors which bind to DNA in control regions and thus regulate myogenesis. All members of this family contain a conserved helix-loop-helix motif which is homologous to the myc family proteins. These factors are only found in skeletal muscle. Members include the myoD protein (MYOD PROTEIN); MYOGENIN; myf-5, and myf-6 (also called MRF4 or herculin).  muscle-specific transcription factors; DF: MYOGENIC REG FACTORS   
Examples MyoD Protein; Myogenic Regulatory Factor 5; Myogenin 		Other names Regulatory Factors, Myogenic; Factors, Myogenic Regulatory
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MEF2C protein, rat  0   *Myogenic Regulatory Factors. Biochem Biophys Res Commun 2009 Oct 9;388(1):155-60
MEF2A protein, rat  0   *Myogenic Regulatory Factors *MADS Domain Proteins. Am J Physiol Endocrinol Metab 2008 Sep;295(3):E698-704
Mef2 protein, zebrafish  0   *Myogenic Regulatory Factors *Zebrafish Proteins. Development 2007 Jul;134(13):2511-9
HABP4 protein, human  0   *Myogenic Regulatory Factors. FEBS Lett. 2005 May 9;579(12):2615-22
Mef2 protein, Drosophila  0   *Myogenic Regulatory Factors *Drosophila Proteins.
MEF2D protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
MEF2C protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
MEF2B protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
MEF2A protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
Mef2d protein, mouse  0   *Myogenic Regulatory Factors.
Mef2c protein, mouse  0   *Myogenic Regulatory Factors.
Mef2b protein, mouse  0   *Myogenic Regulatory Factors.
Mef2a protein, mouse  0   *Myogenic Regulatory Factors.
Mdfi protein, mouse  0   *Myogenic Regulatory Factors.
FERD3L protein, human  0   *Nuclear Proteins *Myogenic Regulatory Factors.
HIC protein, human  0   *Myogenic Regulatory Factors. J Biol Chem 2000 Feb 18;275(7):4848-57
XmyogU2 protein, Xenopus  0   *Myogenic Regulatory Factors *Xenopus Proteins. J Biol Chem 2002 Jan 11;277(2):1139-47
XmyogU1 protein, Xenopus  0   *Myogenic Regulatory Factors *Xenopus Proteins. J Biol Chem 2002 Jan 11;277(2):1139-47
lmd protein, Drosophila  0   *Myogenic Regulatory Factors *Drosophila Proteins Zinc Fingers. Development 2001 Nov;128(22):4489-500; Development 2002 Jan;129(1):133-41
MDFI protein, human  183511-66-2   *Myogenic Regulatory Factors. Cell Sep 6;86(5):731-41
BMD2 protein, Branchiostoma floridae  0   *Myogenic Regulatory Factors Chordata, Nonvertebrate Helix-Loop-Helix Motifs. Gene 1996 Jun 1;171(2):231-6
HLH-1 protein, C elegans  0   *Myogenic Regulatory Factors *Caenorhabditis elegans Proteins. Dev Biol 1994 Nov;166(1):133-48
myocyte-specific enhancer-binding factor 2  0   *Myogenic Regulatory Factors. Mol Cell Biol 1992 Sep;12(9):3665-77
myogenic factor 6  0   *Myogenic Regulatory Factors Transcription Factors. EMBO J 1990;9(3):821

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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