encyclopedia of medical concepts
ψ 
ψ 
ψ 

Receptors, Purinergic P2

More information in Books or onNLM PubMed
Definition: A class of cell surface receptors for PURINES that prefer ATP or ADP over ADENOSINE. P2 purinergic receptors are widespread in the periphery and in the central and peripheral nervous system.  general or unspecified; prefer specifics   
Examples Receptors, Purinergic P2Y 		Other names Receptor, ATP; Receptor, ADP; Purinoceptors, P2; Purinoceptor, P2; Purinergic P2 Receptor; P2 Receptors, Purinergic; P2 Receptor, Purinergic; Receptor, Purinergic P2; P2 Purinoceptor; ATP Receptor; ADP Receptor; Receptors, ATP; Receptors, ADP; Purinergic P2 Receptors; P2 Purinoceptors; ATP Receptors; ADP Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MRS 2211  0   *Azo Compounds Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2. Am J Physiol Cell Physiol 2011 Feb;300(2):266-75
RO 85 compound  0   *Pyrazoles *Thiophenes Receptors, Purinergic P2. Bioorg Med Chem Lett 2010 Feb 1;20(3):1031-6
N-(adamantan-1-ylmethyl)-5-((3-aminopyrrolidin-1-yl)methyl)-2-chlorobenzamide  0   *Benzamides Adamantane/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. GSK 314181A620-33
4-(((4-(1-carboxy-1-methylethoxy)-7-methylquinolin-2-yl)carbonyl)amino)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid  0   *Keto Acids *Quinolines Receptors, Purinergic P2. Thromb Res 2008;122(4):523-32
4-((4-(1-(ethoxycarbonyl)-1-methylethoxy)-7-methyl-2-quinolyl)carbamoyl)-5-(4-(ethoxycarbonyl)piperazin-1-yl)-5-oxopentanoic acid  0   *Keto Acids *Quinolines Receptors, Purinergic P2/antagonists & inhibitors. Thromb Res 2008;122(4):523-32
P2Y10 protein, human  0   *Receptors, Purinergic P2. Biochem Biophys Res Commun 2008 Jul 11;371(4):707-12
P2Y14 receptor, rat  0   *Receptors, Purinergic P2. Genomics 2001 Dec;78(3):124-8
(6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro(3,4-d)(1,3)dioxol-4-yl)methyl dihydrogen phosphate  0   Adenosine Monophosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. J Med Chem 2008 Feb 28;51(4):1007-25
8-carboxy-iso-iantheran A  0   *Benzofurans *Sulfuric Acid Esters Receptors, Purinergic P2/agonists. J Med Chem 2007 Nov 15;50(23):5600-7
iso-iantheran B  0   *Benzofurans *Sulfuric Acid Esters Receptors, Purinergic P2/agonists. J Med Chem 2007 Nov 15;50(23):5600-7
iso-iantheran A  0   *Benzofurans *Sulfuric Acid Esters Receptors, Purinergic P2/agonists. J Med Chem 2007 Nov 15;50(23):5600-7
INS 50589  0   Adenosine Monophosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. Platelets 2007 Aug;18(5):346-56
2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate  0   Uridine Triphosphate/*analogs & derivatives Receptors, Purinergic P2/agonists. J Med Chem 2007 Mar 22;50(6):1166-76
p2y9 protein, rat  0   *Receptors, Purinergic P2. J Biol Chem 2007 Feb 23;282(8):5814-24
P2Y14 receptor, human  0   *Receptors, Purinergic P2. Bioorg Med Chem Lett. 2007 Feb 1;17(3):761-6
3-phenacyluridine diphosphate  0   Uridine Diphosphate/*analogs & derivatives Receptors, Purinergic P2/agonists. J Med Chem 2006 Nov 30;49(24):7076-87
AZ 11645373  0   *Thiazoles Receptors, Purinergic P2/antagonists & inhibitors. Br J Pharmacol 2006 Dec;149(7):880-7
P2ry14 protein, mouse  0   *Receptors, Purinergic P2.
P2RY14 protein, human  0   *Receptors, Purinergic P2.
8,8',8'',8'''-(carbonylbis(imino-5,13-benzenetriyl-bis(carbonylimino)))tetrakisnaphthalene-1,3,5-trisulfonic acid  0   Suramin/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. Naunyn Schmiedebergs Arch Pharmacol 2005 Jul;372(1):1-13
AR C109318XX  0   Adenosine/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. Semin Thromb Hemost 2005 Apr;31(2):195-204
INS 48823  0   Uridine Triphosphate/*analogs & derivatives Receptors, Purinergic P2/agonists. J Biol Chem 2005 Apr 29;280(17):16909-15
P2y12 protein, rat  0   *Receptors, Purinergic P2 Platelet Aggregation Inhibitors.
P2Y15 protein, mouse  0   *Receptors, Purinergic P2. J Biol Chem 2004 May 7;279(19):19790-9
Oxgr1 protein, rat  0   *Receptors, Purinergic P2. J Biol Chem 2004 May 7;279(19):19790-9
P2Y13 protein, rat  0   *Receptors, Purinergic P2.
P2ry13 protein, mouse  0   *Receptors, Purinergic P2.
4-(2-iodo-6-methylaminopurin-9-yl)-1-((phosphato)methyl)-2-(phosphato)bicyclo(3.1.0)hexane  0   Adenosine Diphosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. J Med Chem 2003 Nov 6;46(23):4974-87
1-(N,O-bis(isoquinolinesulfonyl)-N-methyltyrosyl)-4-(4-fluorophenyl)piperazine  0   *Arylsulfonates Tyrosine/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. J Med Chem 2003 Apr 10;46(8):1318-29
P2RY13 protein, human  0   *Receptors, Purinergic P2. J Biol Chem 2001 Nov 2;276(44):41479-85
P2cyc receptor  0   *Receptors, Purinergic P2. Thromb Haemost 2000 Sep;84(3):
p2rx3a protein, zebrafish  0   *Receptors, Purinergic P2 *Zebrafish Proteins. J Neurochem. 2000 Oct;75(4):1600-7
6-((4,6,8-trisulfo-1-naphthyl)iminocarbonyl-1,3-(4-methylphenylene)iminocarbonyl-1,3-phenyleneazo)pyridoxal-5'-phosphate  0   Pyridoxal Phosphate/*analogs & derivatives Suramin/*analogs & derivatives Receptors, Purinergic P2. J Auton Nerv Syst 2000 Jul 3;81(1-3):171-7
purinergic P2X8 receptor  0   *Receptors, Purinergic P2 Muscle Proteins. J Biol Chem 2000 May 12;275(19):14401-7
pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate)  0   *Sulfonic Acids Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. Eur J Pharmacol 2000 Jan 17;387(3):R19-R21
2-(2-(6-methylaminopurin-9-yl)ethyl)propane-1,3-bisoxy(diammonium phosphate)  0   *Phosphoric Acid Esters Adenine/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. J Med Chem 2000 Feb 24;43(4):746-55
diquafosol  0 diuridine 5'-(pentahydrogen tetraphosphate) tetrasodium salt  *Polyphosphates *Uracil Nucleotides Ophthalmic Solutions Receptors, Purinergic P2/agonists. J Appl Physiol 1999 Dec;7(6):2191-6
MRS 2220  0   *Azo Compounds Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. J Med Chem 1998 Jun 18;41(13):2201-6
MRS 2219  0   Pyridoxal Phosphate/*analogs & derivatives Receptors, Purinergic P2/agonists. J Med Chem 1998 Jun 18;41(13):2201-6
purinoceptor P2X6  0   *Receptors, Purinergic P2 Neuropeptides. J Neurosci 1998 Mar;18(5):1704-12
P2RY11 protein, human  0   *Receptors, Purinergic P2. J Biol Chem 1997 Dec 19;272(51):31969-73
P2RY8 protein, Xenopus  0   *Receptors, Purinergic P2 *Xenopus Proteins. J Biol Chem 1997 May 9;272(19):12583-90
purinoceptor P2Y4  0   *Receptors, Purinergic P2. Br J Pharmacol 1996 Dec;119(7):1301-3
purinoceptor P2Y6  0   *Receptors, Purinergic P2. Biochem Biophys Res Commun 1996 May 15;222(2):303-8
uniblue A  34293-80-6   *Anthraquinones *Sulfonic Acids Receptors, Purinergic P1/antagonists & inhibitors Receptors, Purinergic P2/antagonists & inhibitors. Br J Pharmacol 1995 Jun;115(3):427-32
LPAR4 protein, human  0   *Receptors, Purinergic P2. J Immunol 1993 Jul 15;151(2):628-36
adenosine 5',5''',P1,P4-tetraphosphate receptor  0   *Receptors, Purinergic P2. Biochemistry 1993 Mar 30;32(12):3119-23
aggregin  0   *Platelet Membrane Glycoproteins Receptors, Purinergic P2. Arch Biochem Biophys 1988;262(1):298
2,2'-pyridylisatogen tosylate  56583-49-4   Isatin/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. Br J Pharmacol 50(3):458P;1974; Br J Pharmacol 53(4):575;1975; Br J Pharmacol 63(2):378P;1978; Br J Pharmacol 63(2):408p;1978; J Pharm Pharmacol 29(9):542;1977; J Pharm Pharmacol 30(5):335;1978

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy