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Gelatinases

More information in Books or onNLM PubMed
Definition: A class of enzymes that catalyzes the degradation of gelatin by acting on the peptide bonds. EC 3.4.24.-.  MATRIX METALLOPROTEINASE 2 and MATRIX METALLOPROTEINASE 9 are available   
Examples Matrix Metalloproteinase 2; Matrix Metalloproteinase 9
Other names Gelatinase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ND 322  0   *Sulfones Arginine/*analogs & derivatives Gelatinases/antagonists & inhibitors. J Med Chem. 2011 Oct 13;54(19):6676-90.
41 kDa collagenase-gelatinase  EC 3.4.24.-   *Multienzyme Complexes *Collagenases *Gelatinases. Zygote 2000;8 Suppl 1:S37-40
CTTHWGFTLC peptide  0   *Peptides, Cyclic Gelatinases/antagonists & inhibitors. Circ Res. 2000 Oct 13;87(8):670-6
CT 1746  0   *Amides Gelatinases/antagonists & inhibitors. Cancer Res 1996 Feb 15;56(4):715-8
CT 543  0   *Morpholines Gelatinases/antagonists & inhibitors. J Cell Sci 1994 Nov;107(Pt 11):3055-64
fibroblast activation protein alpha  EC 3.4.21.-   *Membrane Proteins *Serine Endopeptidases *Gelatinases Antigens, Neoplasm Antigens, Surface Tumor Markers, Biological. Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5657-61
nicotianamine  34441-14-0   Azetidinecarboxylic Acid/*analogs & derivatives Gelatinases/antagonists & inhibitors. Biosci Biotechnol Biochem 1993 Jul;57(7):1107-10
FN-gelatinase  EC 3.4.99.-   *Gelatinases Fibronectins. Matrix 1992 Suppl 1;138-40
progelatinase  EC 3.4.24.-   *Enzyme Precursors *Gelatinases. J Biol Chem 1991;266(20):13064

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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