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Stavudine

More information in Books or onNLM PubMed
Definition: A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.  DF: note short X ref   
Pharmacological Action Anti-HIV Agents; Antimetabolites; Reverse Transcriptase Inhibitors 		Other names 2',3'-Didehydro-3'-deoxythymidine; D4T; BMY27857; BMY 27857; 2',3' Didehydro 3' deoxythymidine; Stavudine, Monosodium Salt; Bristol-Myers Squibb Brand of Stavudine; Bristol-Myers Brand of Stavudine; BMY-27857; 2',3'-Didehydro-2',3'-dideoxythmidine; ZeritDrugs* : ZERIT; STAVUDINE; ZERIT XR
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
chitosan-O-isopropyl-5'-O-d4T monophosphate conjugate  0   *Stavudine *Chitosan Prodrugs. Bioorg Med Chem Lett. 2009 May 1;19(9):2566-9
triomune  0   *Stavudine *Lamivudine *Nevirapine Drug Combinations. Rev Med Liege 2009 Jan;64(1):32-6
5-diacetoxymethyl-cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine  0   *Thymine Nucleotides Stavudine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2007;26(6-7):861-4
4'-cyano-2',3'-didehydro-2',3'-dideoxythymidine  0   Stavudine/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2004;(48):41-2
GPO-vir  0   *Stavudine *Lamivudine *Nevirapine. J Med Assoc Thai 2006 Sep;89(9):1472-8STAVUDINE; LAMIVUDINE; EFAVIRENZ; STAVUDINE; LAMIVUDINE; NEVIRAPINE; STAVUDINE; LAMIVUDINE; STAVUDINE; LAMIVUDINE W/NEVIRAPINE
4'-ethynylstavudine  0   Stavudine/*analogs & derivatives. Antivir Chem Chemother 2005;16(4):217-21
4'-cyano-2',3'-didehydro-3'-deoxythymidine  0   Stavudine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2004;23(4):647-54
2',3'-didehydro-3'-deoxy-4'-ethynylthymidine  0   Stavudine/*analogs & derivatives. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3775-7
3'-deoxythymidin-3'-yl methyl disulfide  0   *Disulfides Stavudine/*analogs & derivatives. J Med Chem 2003 Jun 19;46(13):2565-8
stampidine  0   *Dideoxynucleotides Thymidine Monophosphate/*analogs & derivatives Stavudine/*analogs & derivatives. Antimicrob Agents Chemother 2002 Nov;46(11):3428-36
Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate  0   *Thymine Nucleotides *Dideoxynucleotides Stavudine/*analogs & derivatives. Curr Top Med Chem. 2002 Oct;2(10):1111-21; Mol Pharmacol. 2000 Nov;58(5):928-35
2',3'-dideoxy-2',3'-didehydrothymidine monophosphate  0   *Dideoxynucleotides Stavudine/*analogs & derivatives. Adv Exp Med Biol 1998;431:753-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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